Tetrahydrofuran
Medchemexpress LLC Tenuifoliside B | 139726-36-6 | 5 MG
Tenuifoliside B is a component isolated from Polygalae Radix. It inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. This compound demonstrates potential cognitive improvement and cerebral protective effects, and it has the potential to be an anti-AD lead compound.
- Demonstrates potential cognitive improvement
- Demonstrates cerebral protective effects
- Has the potential to be an anti-AD lead compound
Medchemexpress LLC Bifenthrin | 82657-04-3 | 99.8% | 50 MG
Bifenthrin is a synthetic pyrethroid insecticide that prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, which disrupts neural function.
- Effective against *A. gambiae* and *C. quinquefasciatus*
- Demonstrates good lethality against susceptible and resistant mosquitoes
- Effectively inhibits blood sucking
- Suitable for development as a mosquito-removal netting material
Medchemexpress LLC Cur61414 | 334998-36-6 | 99.0% | 550.69 | 50 MG
CUR61414 is a novel, potent, and cell-permeable Hedgehog signaling pathway inhibitor with an IC50 of 100-200 nM. It is a small-molecule aminoproline class compound that selectively binds to smoothened (Smo) with a Ki value of 44 nM. CUR-61414 can induce apoptosis in cancer cells without affecting neighboring non-tumor cells.
- Novel, potent, and cell-permeable Hedgehog signaling pathway inhibitor.
- Selectively binds to smoothened (Smo).
- Induces apoptosis in cancer cells without affecting neighboring non-tumor cells.
- Able to arrest proliferation of basal cells within BCC-like lesions and induce apoptosis, leading to complete regression of lesions.
- Causes regression of BCC-like lesions in mice exposed to UV light irradiation, with no overt toxicity observed in surrounding skin.