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Organic compounds with acidic properties, organic acids are generally weak acids incapable of complete dissociation in water. Available in a range of chemical compositions and acid strengths, they can be used for various industrial and everyday applications.
Foxy-5 TFA (CAS No 881188-51-8) is a synthetic peptide that plays a pivotal role in biomedical research particularly in cancer studies Originating from cancer research labs its mechanism of action involves mimicking the Wnt-5a protein which influences key signaling pathways such as the Wnt/ -catenin pathway This regulation is crucial in modulating cancer cell movement and metastasis Foxy-5 TFA demonstrates significant in vitro activity typically ranging from nanomolar to low micromolar concentrations It is commonly used in various cell models including breast and prostate cancer lines and has applications in animal studies for assessing metastasis inhibition Additionally it serves as an essential tool in drug screening to evaluate compounds targeting cancer metastasis pathways Experimental concentrations typically depend on the specific research design
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NH2-UAMC1110 TFA is the trifluoroacetic acid salt of an amino-functionalized derivative of UAMC1110. It is used as a chemical intermediate for the synthesis of FAPI-QS and other FAP-targeting imaging agents and radiotracers. The compound is supplied with high purity and is intended for research and radiochemistry applications where an amino handle is required for conjugation and labeling.
High purity (99.89%) suitable for synthetic and radiochemistry use.
Amino-functionalized derivative for conjugation and labeling.
Trifluoroacetic acid salt form for improved handling and solubility.
Intended for use as an intermediate in FAP-targeting radiotracer synthesis.
Characterized by CAS number 2990021-73-1 and formula C23H24F5N5O5.
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Dendrotoxin-I (DTX-I) TFA is a potent K+ channel blocker with IC50s of 0.13-50 nM for voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6. This neurotoxin has potential for cancer research.
Potent K+ channel blocker.
Targets voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6.
Potential for cancer research.
Shows significant tumor growth inhibition effect in nude mice with MCF-7 cells when combined with hyperthermia (at 5 mg/kg IV).
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Mazdutide TFA is a long-acting synthetic oxyntomodulin analog that acts as a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). It binds to both human and mouse GCGR and GLP-1R, stimulating insulin secretion from mouse islets. This compound is utilized in research for conditions such as obesity and type 2 diabetes.
Functions as a co-agonist of GLP-1R and GCGR.
Binds to human and mouse GCGR and GLP-1R.
Stimulates insulin secretion from mouse islets.
Applicable in studies for obesity and type 2 diabetes.
Significantly reduces body weight and physical intake in diabetic mice with diet-induced obesity.
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