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Organic compounds with acidic properties, organic acids are generally weak acids incapable of complete dissociation in water. Available in a range of chemical compositions and acid strengths, they can be used for various industrial and everyday applications.
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Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. It can be rapidly and completely hydrolyzed to Prednisolone in the plasma.
Possesses anti-inflammatory properties
Offers immunomodulating properties
Rapidly hydrolyzed to Prednisolone in plasma
Used as an analytical standard
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Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. It can be rapidly and completely hydrolyzed to Prednisolone in the plasma.
Synthetic glucocorticoid
Anti-inflammatory and immunomodulating properties
Rapidly and completely hydrolyzed to Prednisolone in plasma
Store at 4°C, sealed, away from moisture (solid)
Store in solvent at -80°C (6 months) or -20°C (1 month)
Soluble in H2O at 50 mg/mL with ultrasonic
For research use only
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DL-Tartaric acid is an orally active and non-racemic mixture of L- and D-tartaric acid with antioxidant activity 14C-labeled DL-Tartaric acid is nephrotoxic[1][2][3]
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ENMD-2076 (CAS 934353-76-1) is a selective inhibitor of Aurora A kinase (IC50 14 nM) and FLT3 (IC50 1 86 nM) with additional inhibitory activity against multiple tyrosine kinases implicated in angiogenesis and cell proliferation including RET FLT4/VEGFR3 SRC CSF1R NTRK1 FGFR1/2 VEGFR2/KDR LCK and PDGFR (IC50 1 86 120 nM) ENMD-2076 disrupts cell cycle progression by arresting cells in the G2/M phase through inhibition of Aurora kinases suppresses the PI3K/AKT signaling pathway and demonstrates cytotoxic effects in hematologic malignancy and solid tumor cell lines (in vitro IC50 25 700 nM) In vivo it reduces tumor growth and angiogenesis in xenograft models supporting its use in cancer research and antiangiogenic studies
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Prednisolone disodium phosphate is a synthetic glucocorticoid that possesses anti-inflammatory and immunomodulating properties. It can be rapidly and completely hydrolyzed to Prednisolone in the plasma.
Acts as a synthetic glucocorticoid
Possesses anti-inflammatory properties
Exhibits immunomodulating properties
Rapidly and completely hydrolyzed to Prednisolone in plasma
Appears as a white to off-white solid
Has a molecular formula of C₂₁H₂₇Na₂O₈P
Features a molecular weight of 484.39
High purity (typically 99.50%)
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ENMD-2076 L- plus -Tartaric acid is a small-molecule inhibitor targeting Aurora kinase A and B It is designed to inhibit the activity of these kinases thereby regulating cell cycle progression and mitotic processes ENMD-2076 L- plus -Tartaric acid exerts its biological activity primarily through the inhibition of Aurora kinase A and B with IC50 values of approximately 14 nM and 350 nM respectively In cell-based studies ENMD-2076 inhibits various breast cancer cell lines suppresses colony formation and induces G2 phase cell-cycle arrest Based on these pharmacological properties ENMD-2076 L- plus -Tartaric acid holds research potential in breast and hematological malignancies
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D-(-)-Tartaric acid diisopropyl ester is a chiral organic reagent used as a chemical building block and biochemical reagent in life-science research. It is the diisopropyl ester derivative of D-tartaric acid and is supplied for use in synthesis, enantioselective transformations, and analytical applications.
Chiral diisopropyl ester of D-tartaric acid for enantioselective synthesis.
Suitable as a reagent and building block in organic synthesis and biochemical assays.
Molecular formula C10H18O6; molecular weight 234.25 g/mol.
Available in multiple package sizes from 10 g to 500 g.
Storage recommendations: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
Product documentation includes a data sheet and safety data sheet.
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Tartaric acid disodium dihydrate (L-(+)-tartaric acid) is an orally active weak organic acid isolated from grapes. It has vasodilatory and antihypertensive effects. It can be used as flavorings and antioxidants in various foods and beverages, as well as in laser frequency doubling and optical limiting applications.
Orally active weak organic acid.
Isolated from grapes.
Exhibits vasodilatory and antihypertensive effects.
Can be used as flavorings and antioxidants in foods and beverages.
Applicable in laser frequency doubling and optical limiting.
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ENMD-2076 (CAS 934353-76-1) is a selective inhibitor of Aurora A kinase (IC50 14 nM) and FLT3 (IC50 1 86 nM) with additional inhibitory activity against multiple tyrosine kinases implicated in angiogenesis and cell proliferation including RET FLT4/VEGFR3 SRC CSF1R NTRK1 FGFR1/2 VEGFR2/KDR LCK and PDGFR (IC50 1 86 120 nM) ENMD-2076 disrupts cell cycle progression by arresting cells in the G2/M phase through inhibition of Aurora kinases suppresses the PI3K/AKT signaling pathway and demonstrates cytotoxic effects in hematologic malignancy and solid tumor cell lines (in vitro IC50 25 700 nM) In vivo it reduces tumor growth and angiogenesis in xenograft models supporting its use in cancer research and antiangiogenic studies
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Fosphenytoin sodium is a proagent of phenytoin with similar anticonvulsant properties. Its primary mechanism of action involves blocking frequency-dependent, use-dependent, and voltage-dependent neuronal sodium channels, thereby limiting the repetitive firing of action potentials.
Effective neuroprotectant against ischemia-induced damage.
Dose-dependently increases the focal seizure (afterdischarge) threshold in kindled rats.
Reduces seizure severity and duration at higher doses in kindled rats.
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Tartaric acid disodium dihydrate is an orally active weak organic acid that can be isolated from grapes. It has vasodilatory and antihypertensive effects. It can be used as flavorings and antioxidants in a range of foods and beverages, and also in laser frequency doubling and optical limiting applications.
Orally active weak organic acid
Can be isolated from grapes
Has vasodilatory and antihypertensive effects
Can be used as flavorings and antioxidants in food and beverages
Can be used in laser frequency doubling and optical limiting applications
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ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1 86 nM 25-fold selective for Aurora A than over Aurora B and less potent to RET SRC NTRK1/TRKA CSF1R/FMS VEGFR2/KDR FGFR and PDGFR ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0 025 to 0 7 M which induces apoptosis and G2/M phase arrest Phase 2
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