Organic Acids

Glycolic Acid, 70%, High Purity, Spectrum™ Chemical

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CAS: 79-14-1 Molecular Formula: C2H4O3 Molecular Weight (g/mol): 76.05 InChI Key: AEMRFAOFKBGASW-UHFFFAOYSA-N IUPAC Name: 2-hydroxyacetic acid SMILES: OCC(O)=O

Glycolic Acid, Technical, 70-72%, Spectrum™ Chemical

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CAS: 79-14-1 Molecular Formula: C2H4O3 Molecular Weight (g/mol): 76.05 InChI Key: AEMRFAOFKBGASW-UHFFFAOYSA-N IUPAC Name: 2-hydroxyacetic acid SMILES: OCC(O)=O

Medchemexpress LLC MRTX-EX185 formic | 2988148-70-3 | 97.23% | C34H35FN6O4 | 1 ML

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MRTX-EX185 formic is a potent KRAS (G12D) inhibitor with an IC50 of 90 nM. It binds to both GDP-loaded and active GNP states of KRAS and KRAS (G12D). This compound exhibits broad-spectrum binding properties and can be utilized for studying various RAS-driven tumors, such as pancreatic cancer.

• Suppresses cell proliferation in KRAS (G12D)-driven SW-1990 pancreatic cancer cells with an IC50 of 70 nM.
• Non-toxic to non-KRAS-dependent cell lines (HEK293 cells).
• Significantly inhibits ERK phosphorylation (p-ERK) in KRAS(G12C)-driven cell lineages.

Medchemexpress LLC MRTX-EX185 formic | 2988148-70-3 | 97.23% | C34H35FN6O4 | 1 MG

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MRTX-EX185 formic is a potent KRAS (G12D) inhibitor (IC50 of 90 nM) that binds to both GDP-loaded and active GNP states of KRAS. It exhibits broad-spectrum binding properties and is used for studying various RAS-driven tumors, such as pancreatic cancer.

• Potent KRAS (G12D) inhibitor with IC50 of 90 nM
• Binds to GDP-loaded and active GNP states of KRAS and KRAS (G12D)
• Exhibits broad-spectrum binding properties including for KRAS WT, G12C, Q61H, G13D, and HRAS
• Suppresses cell proliferation in KRAS (G12D)-driven SW-1990 pancreatic cancer cells (IC50 = 70 nM)
• Non-toxic to non-KRAS-dependent HEK293 cells
• Significantly inhibits ERK phosphorylation in KRAS(G12C)-driven cell lineages

eMolecules​ Ambeed / 12-(3-(Adamantan-1-yl)ureido)dodecanoic acid / 1mg / 625593430 / A1148766 / / 479413-70-2 / [null] / 392.584 / C23H40N2O3

Ambeed / 12-(3-(Adamantan-1-yl)ureido)dodecanoic acid / 1mg / 625593430 / A1148766 / / 479413-70-2 / [null] / 392.584 / C23H40N2O3

Medchemexpress LLC Propanoic-3-13C acid, 2-hydroxy-, monosodium salt, (2S)- | 201595-70-2 | 98.7% | 113.05 | C2(13C)H5NaO3 | 10 MG

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13C-labelled L-lactic acid sodium supplied as a 20% w/w aqueous solution for use in metabolic tracing and analytical applications. The product is provided as a 10 mg aliquot of the labeled sodium salt, with reported purity of 98.7% and molecular weight 113.05. Store frozen at -20°C and protect from light; consult the manufacturer's datasheet/COA for handling and safety information.

• Single 13C label at the 1-position for tracer studies.
• Provided as a 20% w/w aqueous solution for convenient use.
• High chemical purity suitable for analytical applications.
• Ready-to-use sodium salt form for compatibility with biological buffers.
• Store at -20°C and protect from light to maintain stability.