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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
MPP iodide (CAS No 36913-39-0) is commonly used in neurotoxicity studies particularly in research on Parkinson s disease It originates as an active metabolite of MPTP which affects the dopaminergic system in the brain The compound targets mitochondrial complex I leading to disruption of oxidative phosphorylation This mechanism results in oxidative stress and neuronal death MPP iodide exhibits activity in the nanomolar to low micromolar range making it a potent tool for in vitro studies It is frequently applied in cell models such as human neuroblastoma cells and in animal models to simulate Parkinsonian symptoms Its role is significant in drug screening and evaluating neuroprotective agents Experimental concentrations typically depend on the specific research design
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More