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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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MK-4101 is a research-use small-molecule Smoothened (SMO) antagonist that inhibits the Hedgehog signaling pathway and shows antiproliferative and pro-apoptotic activity in tumor cell models. Chemical formula C24H24F5N5O, molecular weight 493.47 g/mol, CAS 935273-79-3, purity ~99.16%.
Smoothened (SMO) antagonist activity with Hedgehog pathway inhibition.
Demonstrated antiproliferative and pro-apoptotic effects in tumor cell models.