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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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1H-Pyrrolo[2,3-b]pyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is suitable for various life science applications, including biochemical assays and general laboratory use. This product is for research use only.
Used as a biological material or organic compound
Suitable for life science research
Available in solid and solvent forms
High purity for reliable results
Multiple solubility protocols for in vitro and in vivo applications
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MyoMed 205 is a small-molecule inhibitor of MuRF1 supplied as a white to off-white solid for research use. It reduces ubiquitination and proteasomal degradation of muscle proteins and has been used in preclinical studies to prevent early diaphragmatic systolic dysfunction and muscle atrophy. Recommended handling includes storage of the powder at low temperature and preparation of solutions in DMSO with warming as needed.
Small-molecule MuRF1 inhibitor for research use.
White to off-white solid with high reported purity.
Soluble in DMSO at up to 25 mg/mL with sonication and warming.
Formulatable for in vivo dosing in 10% DMSO/90% corn oil at ≥ 2.5 mg/mL.
Store powder at -20°C for long-term stability.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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5-Iodo-UTP is an iodinated derivative of uridine triphosphate (UTP) serving as a substrate in RNA synthesis and modification reactions In vitro RNA polymerases incorporate 5-Iodo-UTP into RNA transcripts enabling the production of labeled RNA probes for hybridization assays nucleic acid localization studies and analyses of RNA-protein interactions It also facilitates the investigation of RNA polymerase substrate specificity and the functional mapping of RNA molecules
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Iodo-PEG7-alcohol is a PEG-based PROTAC linker utilized in the synthesis of Proteolysis-Targeting Chimeras (PROTACs). PROTACs are designed to harness the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
Used in the synthesis of PROTACs
PROTACs contain two different ligands connected by a linker
One ligand is for an E3 ubiquitin ligase
The other ligand is for the target protein
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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5-Iodo-dCTP is a bioactive deoxynucleotide analog known to modulate nucleotide metabolism by interfering with specific aspects of DNA synthesis Through incorporation into nucleic acids it disrupts normal DNA replication processes allowing detailed exploration of nucleotide biosynthesis pathways Experimentally 5-Iodo-dCTP serves as a molecular tool to probe polymerase enzyme function and analyze mechanisms underlying DNA synthesis fidelity It is commonly employed in molecular biology investigations facilitating studies on disease-associated disruptions in nucleic acid metabolism
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2-Iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Biochemical reagent
Can be used as a biological material or organic compound
Used for life science related research
Reagent for preparing human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
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