Organic acids and derivatives
eMolecules Ambeed Benzyl propiolate 250mg 784395630 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
Ambeed Benzyl propiolate 250mg 784395630 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
eMolecules 3842-86-2 | Diethyl (2-(dimethylamino)-2-oxoethyl)phosphonate | Synthonix - Stock | MFCD30474919 | 223.209 | C8H18NO4P | 95.000 | CCOP(=O)(CC(=O)N(C)C)OCC | 1g | 495867764
Diethyl (2-(dimethylamino)-2-oxoethyl)phosphonate | Synthonix - Stock | 3842-86-2 | MFCD30474919 | 223.209 | C8H18NO4P | 95.000 | CCOP(=O)(CC(=O)N(C)C)OCC | 1g | 495867764
Medchemexpress LLC Avitinib maleate | 1557268-88-8 | 99.9% | 603.60 | 50 MG
Avitinib maleate (Abivertinib maleate) is a third-generation, irreversible and orally active selective EGFR inhibitor. It also functions as a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. It demonstrates anticancer effects.
- Third-generation, irreversible, and orally active selective EGFR inhibitor.
- Potent against EGFR L858R, EGFR T790M, and wild-type EGFR.
- BTK inhibitor.
- Induces apoptosis.
- Inhibits phosphorylation of BTK in mantle cell lymphoma.
- Shows anticancer effects.
Selleck Chemical LLC Pimethixene maleate S3913-5mg
Pimethixene (Pimetixene) maleate an antihistamine anntimigraine agent and antiserotonergic compound is a highly potent antagonist of a broad range of monoamine receptors including a variety of serotonin receptors Pimethixene maleate inhibits 5-HT2A 5-HT2B 5-HT2C 5-HT1A 5-HT1B 5-HT6 5-HT7 Adrenergic -1A Dopamine D1 Receptor Dopamine D2 Receptor Dopamine D4 4 Receptor Histamine H1 Receptor Muscarinic M1 and Muscarinic M2 with pKi of 10 22 10 44 8 42 7 63 5 7 30 7 28 7 61 6 37 8 19 7 54 10 14 8 61 and 9 38 respectively
Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MG
Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic, serving as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is valuable in the research of schizophrenia and bipolar disorder.
- Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B, and D3 receptors compared to D2 receptor affinity.
- Demonstrated anxiolytic-like effects in animal models.
- Used for treating schizophrenia and bipolar I disorder.
Apexbio Technology LLC NB-598 Maleate 155294-62-5 10mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
Selleck Chemical LLC Tegaserod Maleate S5401-1g
Tegaserod Maleate(HTF-919) is a hydrogen maleate salt form of tegaserod which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors It has limited affinity for 5-HT1 receptors and no appreciable affinity for other 5-HT receptors muscarinic adrenergic dopaminergic or opiate receptors
Medchemexpress LLC Velnacrine maleate | 118909-22-1 | HY-W011246 | 98.0% | 330.34 | 100 MG
Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease.
- Orally active
- Cholinesterase inhibitor
- Used for research of Alzheimer's disease
Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 ML
Tegaserod maleate is an orally active serotonin receptor 4 (HTR4) agonist and a 5-HT2B receptor antagonist. It demonstrates anti-tumor activity by inducing tumor cell apoptosis and blunting PI3K/Akt/mTOR signaling. It is also being researched for its potential in treating irritable bowel syndrome (IBS) and diabetic gastropathy.
- Potent agonist of 5-HT4 receptor
- Antagonist of 5-HT2B receptor
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Accelerates gastric emptying rate
Medchemexpress LLC (S)-Timolol maleate | 26921-17-5 | 99.8% | 432.49 | 50MG
(S)-Timolol maleate is a non-cardioselective hydrophilic β-adrenoceptor blocker, commonly used as a standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. It can also be used for hypertension, angina pectoris, and myocardial infarction. As a chiral compound with one asymmetric carbon, the (S)-enantiomer is a non-cardioselective β-adrenergic blocker, with the (R)-isomer having lower biological activity.
- Non-cardioselective hydrophilic β-adrenoceptor blocker
- Used for intraocular pressure (glaucoma)
- Used for hypertension, angina pectoris, and myocardial infarction
- Single (S)-enantiomer
Medchemexpress LLC Ilginatinib maleate | 1354799-87-3 | 99.87% | 505.50 | 50 MG
Ilginatinib maleate | 1354799-87-3 | 99.87% | 505.50 | 50 MG
Medchemexpress LLC NB-598 Maleate | 155294-62-5 | 99.4% | 565.74 | 1 ML
NB-598 Maleate | 155294-62-5 | 99.4% | 565.74 | 1 ML
Medchemexpress LLC Enalapril maleate | 76095-16-4 | 100.0% | 1 ML
Enalapril maleate is an active metabolite of enalapril and a potent angiotensin-converting enzyme (ACE) inhibitor. As a prodrug, it is rapidly metabolized to enalaprilat, which helps regulate blood pressure by targeting the renin-angiotensin-aldosterone system (RAAS). It is used in the treatment of essential or renovascular hypertension and symptomatic congestive heart failure.
- Active metabolite of enalapril
- Angiotensin-converting enzyme (ACE) inhibitor
- Prodrug that converts to enalaprilat
- Potent and competitive ACE inhibitor
- Used to treat hypertension
- Used to treat congestive heart failure