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Organic compounds with acidic properties, and will commonly have carboxylic acids or similar functional groups in their structure. Derived compounds are also included.
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Sodium citrate (CAS 68-04-2) is a tricarboxylate anion derived from citric acid commonly supplied as a highly water-soluble white crystalline material Functioning as an alkalinizing agent sodium citrate acts by neutralizing hydrogen ions in physiological fluids thereby increasing systemic and urinary pH This buffering action is leveraged in studies of acid-base physiology metabolic acidosis and renal function In biomedical research sodium citrate is also frequently utilized as an anticoagulant in blood specimen preparation and as a component in cell culture systems requiring controlled pH environments
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3-Aminophenylboronic acid is an organoboron reagent used as a building block in organic synthesis and biochemical research. It participates in cross-coupling reactions and enables boronic-acid-based functionalization of materials, for example in nanoparticle conjugation and glycoprotein sensing. Supplied as a high-purity solid, it is suitable for analytical and preparative laboratory work.
High purity suitable for research.
Useful in Suzuki-Miyaura and other cross-coupling reactions.
Reacts with diols for reversible covalent binding to saccharides.
Enables functionalization of nanomaterials and sensors.
Available in multiple pack sizes for lab-scale and bulk use.
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Maleimido-tri(ethylene glycol)-propionic acid is a PEG-based maleimide linker used for site-specific cysteine conjugation in bioconjugation workflows. It combines a maleimide reactive group, a triethylene glycol spacer, and a propionic acid terminus to improve solubility and enable downstream coupling reactions.
Provides a maleimide reactive group for cysteine-specific conjugation.
Contains a triethylene glycol spacer to increase solubility and flexibility.
Features a terminal propionic acid for further derivatization or coupling.
Suitable for ADC linker synthesis and PEG-based PROTAC linkers.
Available in small research pack sizes, including 250 mg.
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A hydroxamate-based, long-chain fatty acid that reversibly inhibits MMP-2 (Ki = 1.6 µM); attenuates cancer cell migration and has been shown to preserve blood-brain barrier function in a rat model of pneumococcal meningitis
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Stigmasterol hemisuccinate (STEMS) is a stigmasterol derivative that is responsive to changes in pH. Stigmasterol is a naturally occurring phytosterol lipid that is growing in the bioprocessing space for its ability to improve lipid nanoparticle (LNP)-based mRNA transfection efficiency. Conjugation to hemiscuccinate has been shown to improve the cellular uptake in acidic microenvironments, such as those around tumors.Key application(s): LNP, acid-delivery systems
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Oxamic acid is a small-molecule inhibitor targeting lactate dehydrogenase A (LDH-A) It is designed to inhibit LDH-A thereby disrupting the conversion of pyruvate to lactate during glycolysis and interfering with the glycolytic pathway Oxamic acid exerts its biological activity primarily through inhibition of LDH-A activity Based on these pharmacological properties oxamic acid holds research potential in studies of tumor metabolism investigation of metabolic vulnerabilities in cancer cells and screening of potential anti-cancer agents targeting glycolytic pathways
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Oxamic acid is a small-molecule inhibitor targeting lactate dehydrogenase A (LDH-A) It is designed to inhibit LDH-A thereby disrupting the conversion of pyruvate to lactate during glycolysis and interfering with the glycolytic pathway Oxamic acid exerts its biological activity primarily through inhibition of LDH-A activity Based on these pharmacological properties oxamic acid holds research potential in studies of tumor metabolism investigation of metabolic vulnerabilities in cancer cells and screening of potential anti-cancer agents targeting glycolytic pathways
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10-Hydroxydecanoic acid (nan) is a small molecule that modulates inflammation and immune response by influencing intracellular signaling cascades and enzyme activities It acts primarily through suppression of NF- B pathway activation and interference with interferon regulatory factor 1 expression leading to reduced production of pro-inflammatory cytokines Based on these pharmacological properties 10-Hydroxydecanoic acid holds research potential in inflammation-associated conditions and immune regulation studies
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10-Hydroxydecanoic acid (nan) is a small molecule that modulates inflammation and immune response by influencing intracellular signaling cascades and enzyme activities It acts primarily through suppression of NF- B pathway activation and interference with interferon regulatory factor 1 expression leading to reduced production of pro-inflammatory cytokines Based on these pharmacological properties 10-Hydroxydecanoic acid holds research potential in inflammation-associated conditions and immune regulation studies
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