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An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An epoxide metabolite of DHA; formed from DHA by various CYP isoforms; suppresses hCLS formation and liver fibrosis in wild-type mice in a model of NASH at 100 ng/animal, i.p., intraplantar administration induces acute mechanical hyperalgesia in mice
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Hexamethylene bisacetamide (HMBA) is a small-molecule differentiation inducer and bromodomain inhibitor used as a research reagent to promote cell differentiation, inhibit proliferation, and investigate apoptosis-related signaling pathways in cell biology and cancer research. It is provided for laboratory use in small pack sizes suitable for in vitro and analytical applications.
Research-grade differentiation inducer for cell biology assays.
Reported to cross the blood-brain barrier in preclinical studies.
Induces apoptosis via Notch1, Bcl-2, and p53 signaling pathways.
High purity for analytical and in vitro applications (≈99.6%).
Chemical formula C10H20N2O2 and molecular weight 200.28 g·mol⁻¹.
Available in small pack sizes suitable for research workflows.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More