Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist. It acts as an agonist for α1D, α1B, and α1A receptors, promoting cardiac fibroblast proliferation and activating the Ca(2+)/CaN/NFAT pathway, which mediates phenylephrine-induced cardiac fibroblast proliferation.
- Selective α1-adrenoceptor agonist
- Targets adrenergic receptor and endogenous metabolite
- Suitable for cardiovascular disease, endocrinology, and cancer research
- Promotes cardiac fibroblast proliferation
- Activates CaN and evokes NFAT3 nuclear translocation
- Used in laboratory chemicals and substance manufacturing