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A polyphenol with diverse biological activities; active against MRSA at 0.01 µg/ml; prevents hexavalent chromium-induced formation of ROS and NOS in a concentration-dependent manner and increases GSH in isolated human erythrocytes; selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM); inhibits proliferation of HT-29 cells at 362 µM but not HCT116 cells at 100 µM
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A reducing sugar; increases levels of ROS in HL-60 human leukemia cells at 15 mM; induces tubulogenesis and migration of BAE cells at 10 µM; topical administration of 2-deoxy-D-ribose increases blood vessel formation and accelerates wound healing in a rat full-thickness cutaneous wound model
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule asembly and causes aberant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent. Alternative name: Vincaleukoblastine . sulfate. Purity: ≥98% (HPLC). Appearance: White to light yellow crystalline powder. Solubility: Soluble in DMSO, methanol or water (25mg/ml). Long Term Storage: -20°C.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More