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A-205804 is a small-molecule research inhibitor that selectively reduces E-selectin and ICAM-1 expression and is used in preclinical studies of inflammatory and immune-related pathways. It demonstrates low-nanomolar potency in cellular assays and is typically supplied as a solid for formulation and dosing in laboratory research.
Potent inhibitor of E-selectin and ICAM-1 (IC50 ≈ 20 nM and 25 nM)
Orally bioavailable small molecule
Suitable for in vitro and in vivo preclinical research
Molecular formula C15H12N2OS2 and molecular weight ≈ 300.4 g/mol
Supplied as solid material for formulation and dosing
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ZTA-261 is a highly selective and low toxic thyroid hormone receptor β subtype (THR-β) agonist that reduces body weight and visceral fat through a liothyronine mediated pathway. It can be used in the study of lipid metabolism and obesity prevalence.
Highly selective THR-β agonist
Low toxicity
Reduces body weight and visceral fat
Useful for lipid metabolism studies
Useful for obesity prevalence studies
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
LP-261 is a potent, orally active anti-mitotic agent. It demonstrates inhibition of in vitro tubulin polymerization with an EC50 of 3.2 μM. This compound has shown efficacy in inhibiting the growth of human non-small-cell lung tumors (NCI-H522) in vivo, making it a valuable tool for cancer research.
Potent anti-mitotic agent.
Orally active.
Inhibits in vitro tubulin polymerization.
Effective against human non-small-cell lung tumors (NCI-H522) in vivo.
Useful for cancer research applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More