Phenylpropanoids and polyketides
Apexbio Technology LLC Tacrolimus monohydrate 109581-93-3 100mg
Tacrolimus monohydrate also identified as FK506 monohydrate is a macrolide immunosuppressive compound functioning via inhibition of calcineurin-mediated signaling pathways Specifically tacrolimus forms a complex with FK506-binding protein (FKBP12) subsequently blocking calcineurin phosphatase activity thus suppressing T-cell activation and diminishing interleukin-2 (IL-2) transcription levels In cellular assays tacrolimus demonstrates inhibition of calcineurin with IC50 values typically ranging between 0 1-1 0 nM Due to its targeted modulation of immune signaling this compound remains widely utilized in biomedical research particularly for investigations related to immune response mechanisms autoimmune disorder models transplantation biology and signal transduction pathways relevant to lymphocyte activation and cytokine expression
Cayman Chemical 7-EthoxycoumarIn 1g
A CYP450 substrate; undergoes O-deethylation by various CYP isoforms; has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea
Accela Chembio Inc 4-methylcinnamic Acid | 100g | 1866-39-3 | MFCD00002697 | 97+% | Shelf Life: 2160 Days | Regular
4-methylcinnamic Acid | 100g | 1866-39-3 | MFCD00002697 | 97+% | Shelf Life: 2160 Days | Regular
Medchemexpress LLC HY-N7127 100mg Medchemexpress, (E)-m-Coumaric acid CAS:14755-02-3 Purity:>98%
Medchemexpress, HY-N7127 100mg (E)-m-Coumaric acid CAS:14755-02-3 (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2-phenylacetophenone | 451-40-1 | MFCD00003081 | 10g
2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization[1]
Medchemexpress LLC Genistein 7-β-d-glucuronide | 38482-81-4 | MFCD24849233 | 98.8% | 446.36 | C21H18O11 | 5 MG
Genistein 7-β-d-glucuronide is a natural isoflavone glucuronide reported to inhibit tubulogenesis and endothelial migration. It is provided as a research reagent and is characterized by formula C21H18O11 and molecular weight 446.36.
- High purity (98.8%) suitable for analytical and biological studies.
- Stable storage recommendations included for long-term and short-term preservation.
- Available in small milligram quantities for laboratory experiments.
- Suitable for studies of endothelial cell function and tubulogenesis.
- Provided with supplier characterization data for research reproducibility.
Medchemexpress LLC Entacapone acid | 160391-70-8 | 98.9% | 250.16 g/mol | C10H6N2O6 | 1MG
Entacapone acid (Tyrphostin AG1290) is a research-grade tyrosine kinase inhibitor (CAS 160391-70-8) used as a biochemical tool to study kinase activity and hepatic protein synthesis. It is supplied as a purified powder with defined storage conditions for stability and long-term use.
- High purity: 98.9%
- Molecular weight: 250.16 g/mol
- Chemical formula: C10H6N2O6
- Reported biological activity: reduces hepatic protein synthesis in vivo
- Available in small research pack sizes, including 1 mg
- Storage: powder -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month)
Medchemexpress LLC Biochanin A | 491-80-5 | MFCD00006839 | 98.7% | C16H12O5 | 10MG
Biochanin A (standard) is an analytical reference standard of the isoflavone Biochanin A (CAS 491-80-5) intended for use as a chromatographic and mass-spectrometry reference in qualitative and quantitative method development. Supplied as a powder, it offers high chromatographic purity and defined storage recommendations to preserve stability.
- High purity suitable for reference and quantitative analysis.
- Validated for use in LC, GC, and mass spectrometry workflows.
- Available in small pack sizes for analytical testing.
- Molecular formula C16H12O5 and molecular weight 284.26 g/mol.
- Store as powder at low temperature to maintain stability.
Cayman Chemical HesperIdIn methylchalconC 100g
A C. aurantium extract that contains hesperidin methylchalcone, among other compounds
Medchemexpress LLC Hydrocinnamic acid-d5 | 35845-62-6 | 99.7% | 155.21 g/mol | C9H5D5O2 | 100mg
Hydrocinnamic acid-d5 is the deuterium labeled Hydrocinnamic acid[1] Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2]
Medchemexpress LLC Genistein 8-c-glucoside | 66026-80-0 | 1 ML
Genistein 8-c-glucoside (G8CG) is a glucoside for research use only that induces mitochondrial membrane depolarization and apoptosis.
- Induces mitochondrial membrane depolarization
- Induces apoptosis
- For research use only
Apexbio Technology LLC Daidzein 486-66-8 1g
Daidzein is an isoflavone compound derived from soybeans structurally classified as a phytoestrogen with structural similarity to endogenous estrogen It has been widely investigated for its potential in biomedical research particularly in oncology and cell biology studies Daidzein exhibits anticancer-related biological activity possibly via modulation of hormonal signaling pathways and interference with cell cycle progression as exemplified by inducing cell cycle arrest at the G1 phase in cultured mammalian cells Additionally it demonstrates antioxidant properties providing protective effects against oxidative stress-mediated cell injury such as hepatic cellular damage induced by chemical carcinogens Daidzein is thus employed in studies focused on hormone-dependent tumorigenesis cell-cycle regulation mechanisms and oxidative-stress-induced cellular responses