Macrolides and analogues
Macrolides and analogues
5Z-7-Oxozeaenol
CAS: 66018-38-0 Molecular Formula: C19H22O7 Molecular Weight (g/mol): 362.378 MDL Number: MFCD12912700 InChI Key: NEQZWEXWOFPKOT-UHFFFAOYSA-N Synonym: 8,9,16-trihydroxy-14-methoxy-3-methyl-4,8,9,10-tetrahydro-3h-2-benzoxacyclotetradecine-1,7-dione PubChem CID: 53442201 IUPAC Name: 5,6,15-trihydroxy-17-methoxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,8,15,17-pentaene-7,13-dione SMILES: CC1CC=CC(=O)C(C(CC=CC2=CC(=CC(=C2C(=O)O1)O)OC)O)O
Abcam Epothilone B, Microtubule stabilizing agent.
This product is for research use only and not for diagnostic or therapeutic procedures. Customer is granted a limited, non-exclusive license for internal research and shall not attempt to reverse engineer.
Epothilone B, Microtubule stabilizing agent.
Cayman Chemical 5Z 11Z 15R15HydroxyeIcosa
A potent inhibitor of B-RafV600E (Kd 14 nM in an in vitro binding assay) blocks B-RafV600E dependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC50s 78 and 60 nM respectively) displays good oral bioavailability
Cayman Chemical 5Z 11Z 15R15HydroxyeIcosa
A potent inhibitor of B-RafV600E (Kd 14 nM in an in vitro binding assay) blocks B-RafV600E dependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC50s 78 and 60 nM respectively) displays good oral bioavailability
Selleck Chemical LLC Zearalenone
Zearalenone (F2 toxin RAL) is a non-steroidal estrogenic mycotoxin that acts by binding the estrogen receptor (ER)
AdipoGen Zearalenone
Chemical. CAS 17924-92-4. Formula C18H22O5. MW 318.4. Isolated from Fusarium graminearum. Resorcylic acid lactone. Mycotoxin. Regulator of fungal morphogenesis. Mycoestrogen with anabolic and uterotrophic activity. Ecdysteroid antagonist. Gonadotropin inhibitor. Interleukin antagonist. Apoptosis inducer. Analytical standard in food industry.
Cayman Chemical 5Z 2E-CU-3 10mg
An ACC inhibitor (IC50s 3.5 and 4.1 nM for human ACC1 and ACC2 respectively) inhibits production of palmitate and total fatty acid content in A549 cells at 500 nM induces apoptosis and ER stress in A549 cells at 500 nM inhibits fatty acid synthesis and reduces tumor growth in an A549 mouse xenograft model at 25 mg/kg twice per day
Cayman Chemical 5Z 2E-CU-3 25mg
A coumarin with antiplatelet activity inhibits ADP-induced platelet aggregation in vitro
Cayman Chemical 5Z-7-Oxozeaenol 1mg
A quinone which inhibits topoisomerase I at 25 M and transglutaminase (IC50 5 M) reduced toBlapachone hydroquinone by NQO1 generating ROS during its reversion toBlapachone sensitizes cancer cells to radiation suppresses NF-KB activation and drives apoptosis
TARGETMOL CHEMICALS INC Epothilone B 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Patupilone may cause complete cell-cycle arrest. Purity 99.48%
TARGETMOL CHEMICALS INC ZEARALENONE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Zearalenone (F2 toxin) is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in cattle pigs and sheep with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts. purity: 99%
Abcam Epothilone D, Microtubule-stabilizing agent.
This product is for research use only and not for diagnostic or therapeutic procedures. Customer is granted a limited, non-exclusive license for internal research and shall not attempt to reverse engineer.
Epothilone D, Microtubule-stabilizing agent.
Sigma Aldrich Fine Chemicals Biosciences Zearalenone fungal mycotox25MG
Zearalenone fungal mycotox25MG
Cayman Chemical 5Z-7-Oxozeaenol 5mg
A quinone which inhibits topoisomerase I at 25 M and transglutaminase (IC50 5 M) reduced toBlapachone hydroquinone by NQO1 generating ROS during its reversion toBlapachone sensitizes cancer cells to radiation suppresses NF-KB activation and drives apoptosis
Selleck Chemical LLC Zearalenone
Zearalenone (F2 toxin RAL) is a non-steroidal estrogenic mycotoxin that acts by binding the estrogen receptor (ER)
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