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Phenylpropanoids and polyketides

Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
Cinnamic acids and derivatives (1)
Coumarins and derivatives (2)

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1

Medchemexpress LLC Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester | 1439366-88-7 | 99.7% | 1 ML
SDP

ARN 077 (enantiomer) is the less-active stereoisomer of ARN 077 (also reported as URB913 enantiomer). It is supplied for research use and reported to inhibit rat NAAA with an IC50 of 3.53 μM for the less-active enantiomer. The compound is offered as a 10 mM solution in DMSO (1 mL) and as solid quantities for laboratory use.

  • Supplied as 10 mM solution in DMSO, 1 mL, and as solids for flexibility in experiments.
  • High reported purity (≈99.7%), suitable for research applications.
  • Molecular formula C16H21NO4, molecular weight 291.34 g/mol.
  • Reported CAS number 1439366-88-7 for unambiguous identification.
  • Intended for research use only; not for human or diagnostic use.

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2

Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG
SDP

Palomid 529 is a small-molecule research inhibitor that targets both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2), modulating the PI3K/Akt/mTOR signaling pathway. It has been used in preclinical studies and early clinical research to reduce tumor growth, angiogenesis, and vascular permeability, and has been investigated for neovascular age-related macular degeneration.

  • Dual inhibition of mTORC1 and mTORC2.
  • Documented in peer-reviewed literature and public chemical databases.
  • High reported purity suitable for analytical use.
  • Suitable as an analytical standard and research reagent.
  • Provided with batch-specific certificate of analysis data.

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3

TARGETMOL CHEMICALS INC 7-ACETOXY-4-METHYLCOUMAR 25MG
SDP

Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media a cell membrane environmental mimic to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum. purity: 88%

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