Phenylpropanoids and polyketides
7-(Diethylamino)-3-(1-methyl-2-benzimidazolyl)coumarin 98.0+%, TCI America™
CAS: 41044-12-6 Molecular Formula: C21H21N3O2 Molecular Weight (g/mol): 347.418 MDL Number: MFCD00051349 InChI Key: KZFUMWVJJNDGAU-UHFFFAOYSA-N Synonym: coumarin 30,7-diethylamino-3-1-methyl-1h-benzo d imidazol-2-yl-2h-chromen-2-one,2h-1-benzopyran-2-one, 7-diethylamino-3-1-methyl-1h-benzimidazol-2-yl,ccris 4959,7-diethylamino-3-1-methyl-1h-benzimidazol-2-yl-2h-chromen-2-one,3-2-n-methylbenzimidazolyl-7-n,n-diethylaminocoumarin,7-diethylamino-3-1-methylbenzimidazol-2-yl chromen-2-one,7-diethylamino-3-1-methyl-1h-benzimidazol-2-yl-2-benzopyrone,7-diethylamino-3-1-methyl-1,3-benzodiazol-2-yl chromen-2-one,coumarin 515 PubChem CID: 100335 IUPAC Name: 7-(diethylamino)-3-(1-methylbenzimidazol-2-yl)chromen-2-one SMILES: CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C3=NC4=CC=CC=C4N3C
Coumarin 478 98.0+%, TCI America™
CAS: 41175-45-5 Molecular Formula: C18H19NO2 Molecular Weight (g/mol): 281.355 MDL Number: MFCD00041949 InChI Key: LLSRPENMALNOFW-UHFFFAOYSA-N Synonym: coumarin 106,coumarin 478,2,3,6,7,10,11-hexahydro-1h,5h-cyclopenta 3,4 1 benzopyrano 6,7,8-ij quinolizin-12 9h-one,1h,5h-cyclopenta 3,4 1 benzopyrano 6,7,8-ij quinolizin-12 9h-one, 2,3,6,7,10,11-hexahydro,3-oxa-16-azapentacyclo 10.7.1.0 2 , 1 ?.0?,?.0 1 ?, 2 ? icosa-1,5 9 ,10,12 20-tetraen-4-one,coumarin 107,1h,4 1 benzopyrano 6,7,8-ij quinolizin-12 9h-one, 2,3,6,7,10,11-hexahydro,1h,5h-cyclopenta 3,4 1 benzopyrano 6,7,8-ij quinolizin-12 9h-one, 2,3,6,7,10,11-hexahydro-9ci PubChem CID: 100336 SMILES: C1CC2=C(C1)C(=O)OC3=C4CCCN5C4=C(CCC5)C=C23
Medchemexpress LLC Myricetin 3-O-glucoside | 19833-12-6 | 5 MG
Myricetin 3-O-glucoside is a flavonol found in *Tibouchina paratropica* and Hakmeitau beans. This compound demonstrates a range of biological activities, including anti-Leishmanial, anti-inflammatory, and antimicrobial properties.
- Demonstrates anti-Leishmanial activity
- Demonstrates anti-inflammatory activity
- Demonstrates antimicrobial activity
- Exhibits anti-inflammatory effects in mouse RAW264.7 cells
Medchemexpress LLC Myricetin 3-O-glucoside (Myricetin 3-β-D-glucopyranoside) | 19833-12-6 | 1 MG
Myricetin 3-O-glucoside is a flavonol found in *Tibouchina paratropica* and Hakmeitau beans. It demonstrates anti-Leishmanial, anti-inflammatory, and antimicrobial activities. This product is for research use only.
- Demonstrates anti-Leishmanial activity
- Demonstrates anti-inflammatory activity
- Demonstrates antimicrobial activity
- Found in *Tibouchina paratropica* and Hakmeitau beans
Sigma Aldrich 12-Aminododecanolactam
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Apexbio Technology LLC Genistein(Synonyms: 4',5,7-Trihydroxyisoflavone, Genisteol, Prunetol, Sophoricol, Differenol A), 10mM (in 1mL DMSO), CAS: 446-72-0.
Genistein (CAS 446-72-0) is an isoflavonoid compound that selectively inhibits protein tyrosine kinases enzymes implicated in signaling pathways associated with oncogenic activity and cellular proliferation Genistein inhibits tyrosine kinase activity with an IC50 of approximately 8 M In NIH-3T3 cell assays genistein suppresses epidermal growth factor (EGF)-mediated mitogenesis (IC50 12 M) and insulin-mediated effects (IC50 19 M) additionally inhibiting EGF-induced activation of S6 kinase at a concentration of 6 15 M In animal models oral administration of genistein demonstrates dose-dependent inhibition of prostate adenocarcinoma development highlighting its utility in cancer biology research and potential chemopreventive applications
Apexbio Technology LLC Genistein(Synonyms: 4',5,7-Trihydroxyisoflavone, Genisteol, Prunetol, Sophoricol, Differenol A), 100mg, CAS: 446-72-0.
Genistein (CAS 446-72-0) is an isoflavonoid compound that selectively inhibits protein tyrosine kinases enzymes implicated in signaling pathways associated with oncogenic activity and cellular proliferation Genistein inhibits tyrosine kinase activity with an IC50 of approximately 8 M In NIH-3T3 cell assays genistein suppresses epidermal growth factor (EGF)-mediated mitogenesis (IC50 12 M) and insulin-mediated effects (IC50 19 M) additionally inhibiting EGF-induced activation of S6 kinase at a concentration of 6 15 M In animal models oral administration of genistein demonstrates dose-dependent inhibition of prostate adenocarcinoma development highlighting its utility in cancer biology research and potential chemopreventive applications
AdipoGen Curcumin high purity
Chemical. CAS 458-37-7. Formula C21H20O6. MW 368.4. Synthetic. Originally isolated from turmeric Curcuma longa. Anti-cancer compound. Interferes with multiple cell signaling pathways, including cell cycle cyclin D1 and cyclin E, apoptosis activation of caspases and down-regulation of anti-apoptotic gene products, proliferation HER-2, EGFR and AP-1, survival PI3K/AKT pathway, invasion MMP-9 and adhesion molecules, angiogenesis VEGF, metastasis CXCR-4 and inflammation NF-kappaB, TNF, IL-6, IL-1, COX-2 and 5-LOX. Anti-angiogenic. Anti-metastatic. Anti-invasive. Chemopreventive. Sonic hedgehog Shh signaling pathway modulator. Downregulates Shh and Gli1. Antioxidant. Anti-inflammatory. Potent inhibitor of NF-kappaB, cyclooxygenase-2 COX-2, lipooxygenase LOX, and inducible nitric oxide synthase iNOS NOSII. Downregulates the expression of various proinflammatory cytokines including TNF, IL-1, IL-2, IL-6, IL-8, IL-12 and chemokines. Potent immunomodulator.
Medchemexpress LLC 4-hydroxychalcone | 20426-12-4 | MFCD00016488 | 99.3% | 224.25 g/mol | C15H12O2 | 1 ML
4-Hydroxychalcone is a chalcone metabolite supplied as a 10 mM solution in DMSO for research use. It is reported to inhibit TNF-α-induced NF-κB activation and to exhibit anti-angiogenic and anti-inflammatory effects, providing a high-purity, ready-to-use stock for cell-based and biochemical assays. Handle under recommended storage conditions and protect from light.
- 10 mM solution in DMSO.
- High purity: 99.3%.
- Molecular formula C15H12O2; molecular weight 224.25 g/mol.
- CAS number 20426-12-4.
- Inhibits TNF-α-induced NF-κB pathway; anti-angiogenic and anti-inflammatory activity.
- Store protected from light; in solvent: -80°C up to 6 months, -20°C up to 1 month.