Guanfacine-13C,15N3 is the 13C and 15N labeled version of Guanfacine. Guanfacine is an orally active noradrenergic α2A agonist that selectively targets the α2A receptor subtype. It has been observed to cause hypotension and sedation. This compound is used in research related to various prefrontal cortex (PFC) cognitive disorders, such as Tourette's syndrome and attention deficit hyperactivity disorder (ADHD). The incorporation of stable heavy isotopes into drug molecules, like in Guanfacine-13C,15N3, is primarily for quantitation during drug development, with deuteration specifically noted for its potential impact on pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS