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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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Salcaprozate-d4 (sodium) is a deuterated labeled Salcaprozate (sodium). Salcaprozate sodium (SNAC) is an oral absorption promoter and has potential as a delivery agent for oral forms of heparin and insulin. It can increase passive transcellular permeation across small intestinal epithelia due to increased lipophilicity arising from non-covalent macromolecule complexation.
Used as a tracer.
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Shows no toxicity to Caco-2 cells at certain concentrations.
Improves apparent permeability coefficient of RA and SA-B.
Improves oral absorption of R1 and SAs and enhances bioavailability in rats.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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1 2 3 4 5 6-Hexabromocyclohexane (CAS 1837-91-8) is a small molecule inhibitor targeting Janus kinase 2 (JAK2) It directly suppresses JAK2 tyrosine kinase activity by blocking ligand-induced autophosphorylation Experimental data indicate that treatment with 1 M of the compound for 16 hours decreases JAK2 autophosphorylation by approximately 50% whereas exposure to 50 M essentially abolishes kinase activity Notably it does not exhibit cytotoxicity at concentrations up to 100 M This compound serves as a valuable research tool for studying JAK2 signaling pathways and related cellular processes
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
1 2 3 4 5 6-Hexabromocyclohexane (CAS 1837-91-8) is a small molecule inhibitor targeting Janus kinase 2 (JAK2) It directly suppresses JAK2 tyrosine kinase activity by blocking ligand-induced autophosphorylation Experimental data indicate that treatment with 1 M of the compound for 16 hours decreases JAK2 autophosphorylation by approximately 50% whereas exposure to 50 M essentially abolishes kinase activity Notably it does not exhibit cytotoxicity at concentrations up to 100 M This compound serves as a valuable research tool for studying JAK2 signaling pathways and related cellular processes
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More