Diterpenoids
Medchemexpress LLC Resiniferatoxin | 57444-62-9 | 5 MG
Resiniferatoxin is a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It can be isolated from the Euphorbia resinifera plant. This compound eliminates TRPV1+ primary sensory afferents and blunts cardiac sympathetic afferent reflex for a relatively long period.
- Selective agonist of TRPV1 receptor
- Isolated from Euphorbia resinifera plant
- Eliminates TRPV1+ primary sensory afferents
- Blunts cardiac sympathetic afferent reflex
- For research use only
Medchemexpress LLC Docetaxel | 114977-28-5 | 99.9% | 807.88 | C43H53NO14 | 10 MG
Docetaxel (standard) is an analytical reference of the chemotherapeutic agent docetaxel supplied for research and analytical applications. It acts as a microtubule depolymerization inhibitor that arrests cells at G2/M and promotes apoptosis. The product is provided in small vial sizes for laboratory workflows and is accompanied by supporting documentation (SDS, COA).
- High purity suitable for analytical applications.
- Molecular weight 807.88.
- CAS number 114977-28-5 for unambiguous identification.
- Available in multiple small vial sizes for flexibility in experiments.
- Intended for research and analytical use only.
Medchemexpress LLC Aphidicolin | 38966-21-1 | MFCD00083214 | 25 MG
Aphidicolin is an inhibitor of DNA polymerase α and δ, which functions by interfering with DNA polymerase activity to prevent mitotic cell division. This antibiotic, originating from the mold Cephalosporium aphidicola, is known for its ability to inhibit cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Furthermore, it demonstrates anti-orthopoxvirus activity and enhances apoptosis when induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
- Inhibits DNA polymerase α and δ
- Prevents mitotic cell division
- Functions as an antibiotic
- Inhibits cellular deoxyribonucleic acid synthesis
- Inhibits growth of herpes simplex virus
- Exhibits anti-orthopoxvirus activity
- Potentiates apoptosis induced by arabinosyl nucleosides
- Targets DNA/RNA synthesis, HSV, and apoptosis pathways
- Applied in infection and inflammation/immunology research
Medchemexpress LLC Paclitaxel (Standard) | 33069-62-4 | 99.9% | C₄₇H₅₁NO₁₄ | 25 MG
Paclitaxel (Standard) is an analytical standard of Paclitaxel, intended for research and analytical applications. It is a naturally occurring antineoplastic agent that stabilizes tubulin polymerization, causing mitotic arrest, apoptotic cell death, and inducing autophagy.
- Used as an analytical standard for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Naturally occurring antineoplastic agent.
- Stabilizes tubulin polymerization.
- Causes mitotic arrest and apoptotic cell death.
- Induces autophagy.
TARGETMOL CHEMICALS INC DIHYDROTANSHINONE I 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases. purity: 99%
Medchemexpress LLC Paclitaxel | 33069-62-4 | MFCD00869953 | 100.0% | 853.91 g·mol⁻¹ | C47H51NO14 | 10 MG
Paclitaxel is a microtubule-stabilizing antineoplastic reagent used in biological research to inhibit mitosis and induce apoptosis. It is supplied as a solid for preparation of experimental stock solutions and is commonly used in cell culture, in vivo studies, and assay development.
- Stabilizes tubulin polymerization and induces mitotic arrest.
- Used for cell culture, in vivo tumor models, and assay development.
- Supplied as a solid powder suitable for dissolution in DMSO or other organic solvents.
- Storage recommendations: protect from light; solids at 4°C; solutions at -20°C (short term) or -80°C (long term).
- Analytical identity confirmed by LC-MS; batch-specific purity reported by certificate of analysis.
Cayman Chemical Paclitaxel, 33069-62-4, 100 mg
Molecular Formula C47H51NO14, Purity ≥98%, Formula Weight 853.9, Synonyms: NSC 125973; A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms.