Diterpenoids
Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | MFCD09028094 | 396.39 | 50 MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, acting as an inhibitor of store-operated Ca2+ entry (SOCE), and is utilized in the treatment of cardiovascular disorders. It is intended for research use only and is not sold to patients.
- Acts as an inhibitor of store-operated Ca2+ entry (SOCE).
- Used to treat cardiovascular disorders.
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation.
- Suppresses TRPC1 and TRPC6 expression and reverses suppressive effects on basal calcium concentration and SOCE in hypoxic PASMCs.
- Inhibits CYP3A4 activity.
- Attenuates scopolamine-induced cognitive dysfunctions and improves the cholinergic system.
- Increases superoxide dismutase activity and decreases oxidative stress markers.
- Alleviates hypoxia-induced changes in chronic hypoxia PH rat model.
- Prevents peritoneal adhesion.
Apexbio Technology LLC Phytol 150-86-7 100g
Phytol is a naturally occurring diterpene alcohol derived from chlorophyll metabolism serving as an activator for retinoid X receptors (RXRs) RXRs are nuclear hormone receptors implicated in transcriptional regulation and cellular differentiation through ligand-dependent signaling pathways involving vitamins and hormones Phytol activates RXRs displaying Ki values ranging from 2 3 to 67 2 M In mammals phytol is metabolized to phytanic acid a reaction regulated by peroxisome proliferator-activated receptor (PPAR ) Additionally phytol interacts with GABA A receptors exhibiting sedative and anxiolytic properties and has been investigated as an antischistosomal candidate in animal models
Sigma Aldrich Fine Chemicals Biosciences Aphidicolin from Nigrospora sphaerica | 38966-21-1 | MFCD00083214 | 1mg
Aphidicolin from Nigrospora sphaerica | 38966-21-1 | MFCD00083214 | 1mg
Medchemexpress LLC Tanshinone I | 568-73-0 | MFCD00210563 | 98.8% | 276.29 g/mol | C18H12O3 | 10 MG
Analytical standard of Tanshinone I supplied as a high-purity reference material for research and analytical use. It is intended for qualitative and quantitative analysis, method development, calibration, and identity/purity testing by techniques such as liquid chromatography, gas chromatography, and mass spectrometry. Reported purity ≈98.8% and CAS 568-73-0.
- Intended for analytical applications such as LC, GC, and MS.
- High purity suitable for calibration and quantitative analysis.
- Useful for method development and identity and purity testing.
- Available in small research quantities for laboratory use.
Cayman Chemical Paclitaxel, 33069-62-4, 100 mg
Molecular Formula C47H51NO14, Purity ≥98%, Formula Weight 853.9, Synonyms: NSC 125973; A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms.