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A quinolone antibiotic; active against Gram-positive and Gram-negative bacteria including S. aureus and E. coli (MICs = 10 and 1 UG/ml, respectively); inhibits growth of nalidixic acid-sensitive strains of E. coli in an in vitro model of bacterial cystitis at 10 and 50 mg/L; active against chloroquine-sensitive and -resistant strains of P. falciparum in vitro (IC50s = 41.4 and 14.4 UG/ml, respectively) and against hepatic stages of P. yoelii yoelii (IC50 = 21.6 UG/ml)
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A bile acid; formed by 7α-hydroxylation of 27-hydroxycholesterol; precursor in the biosynthesis of chenodeoxycholic acid; levels are increased in patients with neonatal liver disease harboring mutations in CYP7A1, as well as in patients with intrahepatic and extrahepatic cholestasis
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One of several monounsaturated 20-carbon fatty acids; combined C20:1 isomers constitute approximately 70% of the total fatty acid pool in jojoba seed oil
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A component of bacterial peptidoglycan; linked to GlcNAc by β-1,4 linkages in an alternating pattern, as well as to the peptide side chains via its lactyl side chain, in native peptidoglycan
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