Cayman Chemical SalIcylIc AcId 100mg
A diarylnonanoid with diverse biological activities an inhibitor of sphingomyelin synthase 1 and -2 (IC50s 3.5 and 2.5 UM respectively) active against S. aureus B. subtilis and S. durans (MIC 1 Ug/ml for all) and three strains of C. albicans (MICs 4-16 Ug/ml) cytotoxic to A549 A375 Jurkat A431 U937 and MCF-7 cells (IC50s 8.1 26.7 27.4 9.5 27.5 and 9.3 UM respectively) but not non-cancerous cells increases the levels of ROS and induces apoptosis in A549 cells reduces TBARS formation by 28.2 in rat liver mitochondria at 2 Ug/ml reduces stomach ulceration in a mouse model of indomethacin-induced gastric ulcer at 10 15 and 20 mg/kg