Halomethanes
Medchemexpress LLC Pralidoxime (iodide) | 94-63-3 | 25 MG
Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). It reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning.
- Potent reactivator of acetylcholinesterase (AChE).
- Reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent.
- Antidote for organophosphate poisoning.
eMolecules 84192-88-1 | Ambeed | Ac-Glu(OtBu)-OH | 5g | 490499420 | A120632 | MFCD00236754 | 245.275 | C11H19NO5
Ambeed | Ac-Glu(OtBu)-OH | 5g | 490499420 | A120632 | 84192-88-1 | MFCD00236754 | 245.275 | C11H19NO5
eMolecules 93547-88-7 | Ambeed | tert-Butyldiphenylsilanol | 1g | 721418446 | A1524304 | 256.42 | C16H20OSi
Ambeed | tert-Butyldiphenylsilanol | 1g | 721418446 | A1524304 | 93547-88-7 | 256.420 | C16H20OSi
![eMolecules 117718-88-4 | ChemScene | Imidazo[12-a]pyrazin-8-amine | 100mg | 415469202 | CS-0054400 | MFCD09835034 | 134.142 | C6H6N4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455620.PNG-250.jpg)
eMolecules 117718-88-4 | ChemScene | Imidazo[12-a]pyrazin-8-amine | 100mg | 415469202 | CS-0054400 | MFCD09835034 | 134.142 | C6H6N4
ChemScene | 7-Bromo-1H-indazol-3-amine | 250mg | 654744024 | CS-W006669 | 1234616-28-4 | MFCD12406137 | 212.050 | C7H6BrN3
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eMolecules 712349-88-7 | 1-(4-Chloro-2-ethylphenyl)ethanone | ChemScene182.650 | C10H11ClO | 97.000 | CCc1cc(Cl)ccc1C(C)=O | 100mg | 714104666
1-(4-Chloro-2-ethylphenyl)ethanone | ChemScene | 712349-88-7182.650 | C10H11ClO | 97.000 | CCc1cc(Cl)ccc1C(C)=O | 100mg | 714104666
Medchemexpress LLC TEPC466 | 2621957-88-6 | 99.4% | 544.60 | 50 MG
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe that shows high selectivity and sensitivity for detecting the PKM2 protein via the AIE effect. It can be used for PKM2 detection and has been successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. It is a useful tool for cancer diagnosis and research.
- Novel TEPP-46-based aggregation-induced emission (AIE) probe
- High degree of selectivity and sensitivity for the detection of PKM2 protein
- Successfully applied in imaging PKM2 protein in colorectal cancer cells with low toxicity
- Useful tool for cancer diagnosis and research
Medchemexpress LLC Beperidium iodide | 86434-57-3 | MFCD00866899 | 100.0% | 527.44 g/mol | C23H34IN3O3 | 5 MG
Beperidium iodide is the iodide salt of a bioactive compound used as a competitive antagonist of acetylcholine receptors. It is supplied as a small, high-purity research reagent with a reported pA2 of 7.93, intended for use as a pharmacological probe in studies of cholinergic signaling.
- Competitive antagonist of acetylcholine receptors with reported pA2 = 7.93.
- High purity (99.97%) suitable for analytical and experimental use.
- Molecular formula C23H34IN3O3 and molecular weight 527.44 g/mol.
- Available as a 5 mg research pack for laboratory studies.
- Provided as the iodide salt for improved stability and handling.
Medchemexpress LLC Bay-593 | 2413020-56-9 | 99.9% | 476.53 | 100 MG
BAY-593 is an orally active GGTase-I inhibitor that can block YAP1/TAZ signaling in animals and exhibits antitumor activity.
- Orally active GGTase-I inhibitor
- Blocks YAP1/TAZ signaling in animals
- Shows antitumor activity
Medchemexpress LLC Demethylzeylasteral | 107316-88-1 | 480.59 | 20 MG
Demethylzeylasteral | 107316-88-1 | 480.59 | 20 MG
Medchemexpress LLC MPP+ iodide | 36913-39-0 | 100.0% | 297.14 | 50 MG
MPP+ iodide is a toxic metabolite of the neurotoxin MPTP. It causes symptoms of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in the substantia nigra. It is taken up by the dopamine transporter into dopaminergic neurons, where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high-affinity substrate for the serotonin transporter (SERT).
- Toxic metabolite of neurotoxin MPTP.
- Causes Parkinson's disease symptoms in animal models.
- Selectively destroys dopaminergic neurons in substantia nigra.
- Taken up by dopamine transporter into dopaminergic neurons.
- Exerts neurotoxic action on mitochondria by affecting complex I of the respiratory chain.
- High-affinity substrate for the serotonin transporter (SERT).
Apexbio Technology LLC 360A iodide 737763-37-0 10mg
360A iodide (CAS 737763-37-0) is a 2 6-pyridine-dicarboxamide derivative that acts as a selective ligand for G-quadruplex DNA structures By stabilizing telomeric G-quadruplexes 360A inhibits telomerase activity and induces alterations in cell cycle progression notably causing S-phase accumulation in ATM-proficient EBV-lymphocytes Its mechanism of action involves promoting sister telomere fusions via DNA-PKcs-dependent non-homologous end joining (NHEJ) as well as triggering NHEJ and homologous recombination (HR) pathways at telomeres which disrupt mitotic progression 360A has been shown to preferentially bind telomeric G-quadruplex DNA over duplex DNA and to delay growth in HT1080 tumor cells This compound is valuable for investigating telomere biology DNA damage response and G-quadruplex-mediated genomic stability
Medchemexpress LLC N-(4-((4-isopropylpiperazin-1-yl)sulfonylphenyl)-5-pentafluorophenyl)nicotinamide | 1803003-65-7 | 99.9% | 513.54 | 5 MG
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively.
- IC50 for human TRPV4 is 0.26 μM.
- IC50 for rat TRPV4 is 0.39 μM.
- Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Pharmacokinetic analysis has been performed in Wistar rats.
Medchemexpress LLC Tenuazonic acid | 610-88-8 | 5 MG
Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. It inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. It is acutely toxic and functions as a photosystem II (PSII) inhibitor. Additionally, it exhibits antiviral effects on measles virus, enterovirus, and respiratory virus, and has an inhibitory effect on skin cancer.
- Nonhost-selective mycotoxin
- Belongs to the tetramic acids family
- Inhibits protein biosynthesis on ribosomes
- Blocks electron transport beyond the primary quinone receptor (QA)
- Acts as a photosystem II (PSII) inhibitor
- Has antiviral effects on measles virus, enterovirus, and respiratory virus
- Has an inhibitory effect on skin cancer
eMolecules 75-11-6 | Diiodomethane | Oakwood Chemical | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 100g | 537691336
Diiodomethane | Oakwood Chemical | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 100g | 537691336
Medchemexpress LLC Aryl Hydrocarbon Receptor Antibody (YA610) | Predicted band size: 96 kDa; Observed band size: 105 kDa | 50 UL
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody, specifically targeting the Aryl Hydrocarbon Receptor. It is for research use only and not intended for patient use.
- Rabbit-derived recombinant monoclonal antibody
- Targets human Aryl Hydrocarbon Receptor
- Validated for Western Blot and Immunocytochemistry/Immunofluorescence
- Supplied as a liquid in TBS with BSA, glycerol, and sodium azide preservative
- Store at -20°C for up to 1 year
- Plays a role in development, immunity, and cancer
- Regulates angiogenesis, hematopoiesis, and metabolism
- Functions as a ligand-activated transcription factor
- Subcellular localization in cytoplasm and nucleus