Halomethanes
TARGETMOL CHEMICALS INC MPP iodide 50MG
Also available in 1 g, 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells. Purity 99.96%
TARGETMOL CHEMICALS INC TAK-593 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRalpha, and PDFGRbeta, respectively). Purity 99.18%
Medchemexpress LLC TO-PRO-3 iodide 671ug | 157199-63-8 | 671.42 g·mol⁻¹ | C26H31I2N3S | 671 UG
TO-PRO-3 iodide is a far-red monomeric cyanine nucleic acid stain that selectively binds nucleic acids and produces bright nuclear fluorescence in fixed or membrane-compromised cells.
- Provides bright far-red nuclear staining with excitation ≈642 nm and emission ≈661 nm.
- Is cell-impermeant and useful as a viability marker and nuclear counterstain.
- Is suitable for flow cytometry, fluorescence microscopy, and chromosome staining.
- Is supplied as a DMSO solution for convenient dilution to working concentrations.
- Offers high fluorescence enhancement upon nucleic acid binding for sensitive detection.
- Is provided in a small vial format (e.g., 671 μg, 5 mM x 200 μL) for research use.
Medchemexpress LLC RN-1665 | 1803003-65-7 | 99.93% | 513.54 | 50 MG
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively.
- Orally active TRPV4 antagonist.
- Excellent selectivity for related TRP receptors (TRPV1, TRPV3, TRPM8).
- TRPV4 probe for focus screens.
- IC50s: 0.26 μM for hTRPV4, 0.39 μM for rTRPV4.
eMolecules 77532-88-8 | 4-CHLORO-2-CYANOBENZALDEHYDE | AstaTech | MFCD10699538 | 165.580 | C8H4ClNO | 95.000 | Clc1ccc(C=O)c(c1)C#N | 1g | 282986157
4-CHLORO-2-CYANOBENZALDEHYDE | AstaTech | 77532-88-8 | MFCD10699538 | 165.580 | C8H4ClNO | 95.000 | Clc1ccc(C=O)c(c1)C#N | 1g | 282986157
Medchemexpress LLC Aryl Hydrocarbon Receptor Antibody (YA610) | Predicted band size: 96 kDa; Observed band size: 105 kDa | 10 UL
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting the Aryl Hydrocarbon Receptor. It plays a critical role in cellular adaptation to environmental, dietary, microbial, and metabolic cues, influencing development, immunity, and cancer. For research use only.
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Species reactivity: Human
- Immunogen: Synthetic human Aryl Hydrocarbon Receptor peptide (AA range: 735-775)
- Applications: WB (1:1000-1:2000), ICC/IF (1:100-1:500)
- Sensitivity: Endogenous
- Conjugation: Non-conjugated
- Isotype: IgG
- Appearance: Liquid
- Formulation: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide
- Storage: -20°C for 1 year; avoid freeze/thaw cycles
- Shipping: Blue ice
Apexbio Technology LLC 360A iodide 737763-37-0 5mg
360A iodide (CAS 737763-37-0) is a 2 6-pyridine-dicarboxamide derivative that acts as a selective ligand for G-quadruplex DNA structures By stabilizing telomeric G-quadruplexes 360A inhibits telomerase activity and induces alterations in cell cycle progression notably causing S-phase accumulation in ATM-proficient EBV-lymphocytes Its mechanism of action involves promoting sister telomere fusions via DNA-PKcs-dependent non-homologous end joining (NHEJ) as well as triggering NHEJ and homologous recombination (HR) pathways at telomeres which disrupt mitotic progression 360A has been shown to preferentially bind telomeric G-quadruplex DNA over duplex DNA and to delay growth in HT1080 tumor cells This compound is valuable for investigating telomere biology DNA damage response and G-quadruplex-mediated genomic stability
eMolecules 70189-88-7 | Ambeed | 3-(Propylamino)propane-12-diol | 250mg | 599119840 | A631978 | MFCD11213268 | 133.191 | C6H15NO2
Ambeed | 3-(Propylamino)propane-12-diol | 250mg | 599119840 | A631978 | 70189-88-7 | MFCD11213268 | 133.191 | C6H15NO2
Medchemexpress LLC Aryl Hydrocarbon Receptor Antibody (YA610) | Predicted: 96 kDa; Observed: 105 kDa | 100 UL
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody. It targets the Aryl Hydrocarbon Receptor and is protein A affinity purified. This antibody is for research use only.
- Rabbit-derived
- IgG monoclonal antibody
- Targets Aryl Hydrocarbon Receptor
- Protein A affinity purified
- Non-conjugated
- Reactive with human samples
- Suitable for Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF) applications
Medchemexpress LLC (-)-Alkannin | 517-88-4 | MFCD00189414 | 99.9% | 288.30 g·mol⁻1 | C16H16O5 | 10 MG
(-)-Alkannin is a naturally occurring naphthoquinone used in research as an apoptosis inducer that can arrest the cell cycle. It is supplied as a high-purity solid suitable for biochemical and cell-based studies, provided in small packaging for limited-scale experiments.
- Apoptosis inducer and cell cycle arrest agent.
- High purity suitable for analytical and biological assays.
- Solid, brown to red appearance for easy handling.
- Available in small package sizes (including 10 mg) for pilot studies.
- Recommended storage conditions provided for powder and solutions.
eMolecules 888329-88-2 | Ambeed | 3-(Phenylethynyl)oxazolidin-2-one | 100mg | 672838128 | A1414173 | 187.198 | C11H9NO2
Ambeed | 3-(Phenylethynyl)oxazolidin-2-one | 100mg | 672838128 | A1414173 | 888329-88-2 | 187.198 | C11H9NO2
eMolecules 20662-88-8 | 2-PHENYLOXAZOLE | AstaTech | MFCD00461764 | 145.161 | C9H7NO | 95.000 | c1coc(n1)-c1ccccc1 | 0.25g | 233627069
2-PHENYLOXAZOLE | AstaTech | 20662-88-8 | MFCD00461764 | 145.161 | C9H7NO | 95.000 | c1coc(n1)-c1ccccc1 | 0.25g | 233627069
![eMolecules 14353-88-9 | Ambeed | [Bis(trifluoroacetoxy)iodo]pentafluorobenzene | 1g | 596568670 | A422899 | MFCD00191612 | 519.993 | C10F11IO4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502452192.PNG-250.jpg)
eMolecules 14353-88-9 | Ambeed | [Bis(trifluoroacetoxy)iodo]pentafluorobenzene | 1g | 596568670 | A422899 | MFCD00191612 | 519.993 | C10F11IO4
Medchem Express | Curcumenol | 5mg | 482204609 | HY-N2259 | 19431-84-6 | MFCD01729508 | 234.339 | C15H22O2
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eMolecules 1056454-88-6 | Ambeed | 2-(3-Bromo-5-chlorophenyl)acetonitrile | 1g | 682930080 | A253355 | MFCD13195464 | 230.49 | C8H5BrClN
AstaTech | 34-DIMETHOXYPYRIDINE | 0.25g | 402181178 | F19595 | 95.000 | 109613-93-6 | MFCD04037427 | 139.154 | C7H9NO2
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