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Filtered Search Results
eMolecules 611168-63-9 | 5-Chloro-2-(tributylstannyl)pyridine | Synthonix - Stock | MFCD10699156 | 402.590 | C17H30ClNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)cn1 | 1g | 525913206
5-Chloro-2-(tributylstannyl)pyridine | Synthonix - Stock | 611168-63-9 | MFCD10699156 | 402.590 | C17H30ClNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)cn1 | 1g | 525913206
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 328000-17-5 | 4-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1ccc(cc1)C1OCCO1 | 100ml | 779536147
4-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix | 328000-17-5253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1ccc(cc1)C1OCCO1 | 100ml | 779536147
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Aobchem (4-(Methoxymethyl)naphthalen-1-yl)(methyl)sulfane | 95% | C13H14OS | 250mg
(4-(Methoxymethyl)naphthalen-1-yl)(methyl)sulfane | 95% | C13H14OS | 250mg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Cinacalcet (hydrochloride) | 364782-34-3 | 99.9% | C22H23ClF3N | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cinacalcet hydrochloride is an orally active, allosteric agonist of the Ca receptor (CaR), used for cardiovascular disease treatment. It is intended for identified uses as laboratory chemicals and in the manufacture of substances.
- Orally active allosteric agonist
- Used for cardiovascular disease treatment
- For research use only
- Purity of 99.88%
- Solid form with melting point of 182.0-182.3°C
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 183545-05-3 | 6-Chloro-3-(tributylstannyl)pyridine | Synthonix - Stock | MFCD01318969 | 402.590 | C17H30ClNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)nc1 | 25g | 525913230
6-Chloro-3-(tributylstannyl)pyridine | Synthonix - Stock | 183545-05-3 | MFCD01318969 | 402.590 | C17H30ClNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)nc1 | 25g | 525913230
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Givinostat (hydrochloride) | 199657-29-9 | 98.1% | 457.95 | 1 ML
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Givinostat (ITF-2357) hydrochloride is an HDAC inhibitor that can penetrate the blood-brain barrier (BBB). It demonstrates inhibitory activity against various HDACs, including HDAC1 (IC50: 198 nM) and HDAC3 (IC50: 157 nM).
- Targets multiple HDACs, including hHDAC1, hHDAC3, hHDAC11, hHDAC6, hHDAC2, hHDAC10, hHDAC7, hHDAC5, hHDAC9, hHDAC8, and hHDAC4.
- Suppresses LPS-induced IL-1β production by over 70%.
- Reduces IL-6 production in PBMCs stimulated with TLR agonists.
- Inhibits JS-1 cell proliferation.
- Reduces serum TNFα in vivo.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 352-34-1 | 1-Fluoro-4-iodobenzene | Ambeed | MFCD00001052 | 222.001 | C6H4FI | 98.000 | Fc1ccc(I)cc1 | 5g | 521423496
1-Fluoro-4-iodobenzene | Ambeed | 352-34-1 | MFCD00001052 | 222.001 | C6H4FI | 98.000 | Fc1ccc(I)cc1 | 5g | 521423496
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC BI-847325 | 1207293-36-4 | 98.15% | 464.56 | 50 MG
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BI-847325 is an ATP competitive dual inhibitor of MEK and aurora kinases (AK). It inhibits the growth and survival of both treatment-naive and drug-resistant melanoma cell lines, decreasing the expression of MEK and Mcl-1 while increasing the expression of pro-apoptotic protein Bim. This compound is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- ATP competitive dual inhibitor of MEK and aurora kinases
- Inhibits MEK2 with an IC50 of 4 nM
- Inhibits aurora kinases with IC50 values of 15 nM for AK-C and 25 nM for AK-A
- Inhibits LCK (5 nM) and MAP3K8 (93 nM) at 1,000 nM
- Induces apoptosis in treatment-naive and drug-resistant xenografted melanoma in vivo
- Click chemistry reagent with an Alkyne group
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Medchemexpress LLC BI-882370 | 1392429-79-6 | MFCD31618072 | 99.2% | 569.67 | C28H33F2N7O2S | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-882370 is a potent, selective small-molecule pan-RAF kinase inhibitor that binds the ATP binding site in the DFG-out (inactive) conformation. It demonstrates sub-nanomolar to low-nanomolar inhibition of BRAF V600E, wild-type BRAF, and CRAF, and is supplied as a high-purity solid for preclinical research applications.
- Potent pan-RAF inhibition with sub-nanomolar to low-nanomolar potency.
- Binds the ATP site in the DFG-out inactive conformation.
- High purity solid suitable for in vitro and in vivo preclinical studies.
- Well-defined chemical identity with confirmed molecular formula and mass.
- Available in small research-scale packaging for dose response experiments.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1374567-99-3 | 5-Fluoropyridin-2-ylmagnesium bromide, 0.25 M in THF | Synthonix200.293 | C5H3BrFMgN | 97.000 | [Br-].Fc1ccc([Mg+])nc1 | 25ml | 722715541
5-Fluoropyridin-2-ylmagnesium bromide, 0.25 M in THF | Synthonix | 1374567-99-3200.293 | C5H3BrFMgN | 97.000 | [Br-].Fc1ccc([Mg+])nc1 | 25ml | 722715541
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 2128716-33-4 | 3-Tetrahydrofuran-yl magnesium bromide, 0.5M in THF | Synthonix | MFCD31536798 | 175.308 | C4H7BrMgO | 95.000 | [Br-].[Mg+]C1CCOC1 | 25ml | 627353740
3-Tetrahydrofuran-yl magnesium bromide, 0.5M in THF | Synthonix | 2128716-33-4 | MFCD31536798 | 175.308 | C4H7BrMgO | 95.000 | [Br-].[Mg+]C1CCOC1 | 25ml | 627353740
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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AdipoGen 5-Hydroxynicotinic acid
Chemical. CAS 27828-71-3. Formula C6H5NO3. MW 139.11. Synthetic A nicotinic acid analog. Substrate analog MHPCO, used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase MHPCO. Also used as building block for synthesis. Hydroxynicotinic acid is formed by the enzymatic action of nicotinate with nicotinic acid hydroxylase or nicotinate hydroxylase.
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eMolecules 1372548-45-2 | Tetrahydropyran-4-ylzinc bromide, 0.50 M in THF | Synthonix230.410 | C5H9BrOZn | 95.000 | [Br-].[Zn+]C1CCOCC1 | 25ml | 627353819
Tetrahydropyran-4-ylzinc bromide, 0.50 M in THF | Synthonix | 1372548-45-2230.410 | C5H9BrOZn | 95.000 | [Br-].[Zn+]C1CCOCC1 | 25ml | 627353819
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 3277-89-2 | 2-Phenylethylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD06200648 | 209.369 | C8H9BrMg | 0.000 | [Br-].[Mg+]CCc1ccccc1 | 25ml | 437237399
2-Phenylethylmagnesium bromide, 0.5M in THF | Synthonix - Stock | 3277-89-2 | MFCD06200648 | 209.369 | C8H9BrMg | 0.000 | [Br-].[Mg+]CCc1ccccc1 | 25ml | 437237399
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1350356-52-3 | (Tetrahydropyran-4-yl)zinc iodide, 0.5M in THF | Synthonix - Stock | MFCD25367665 | 277.410 | C5H9IOZn | 97.000 | [I-].[Zn+]C1CCOCC1 | 100ml | 392990844
(Tetrahydropyran-4-yl)zinc iodide, 0.5M in THF | Synthonix - Stock | 1350356-52-3 | MFCD25367665 | 277.410 | C5H9IOZn | 97.000 | [I-].[Zn+]C1CCOCC1 | 100ml | 392990844
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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