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Filtered Search Results
Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]meth | 1093108-50-9 | 99.4% | 501.50 | 1 MG
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BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). It has IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. This compound shows potential for the treatment of poorly controlled asthma.
- Highly specific and potent antagonist of DP2/CRTH2
- Potential for treating poorly controlled asthma
- Exhibits low nM potency against human or mouse CRTH2 in transfected cells
- Significantly inhibits AHR in mice
- Effectively blocks edema formation and reduces inflammatory infiltrate and skin pathology in drug vehicle-treated animals
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000664924 BI-749327 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000597013 BI-9321 TRIHYDROCHL 10MM/1ML
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Apexbio Technology LLC GSK 5959 901245-65-6 10mg
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GSK 5959 (CAS 901245-65-6) is a selective small-molecule inhibitor targeting the bromodomain of BRPF1 (bromodomain and PHD finger-containing protein 1) By binding specifically to the BRPF1 bromodomain GSK 5959 disrupts its interaction with acetylated histones thereby modulating associated epigenetic regulatory pathways In vitro studies report an IC50 of 80 nM for inhibition of BRPF1 bromodomain activity Due to its favorable cell permeability GSK 5959 is widely utilized in research investigating BRPF1-dependent mechanisms of gene expression and in the exploration of epigenetic contributions to disease models
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eMolecules 56413-95-7 | dichloropyrazine-2,3-dicarbonitrile | Pharmablock | MFCD00191419 | 198.990 | C6Cl2N4 | 97.000 | Clc1nc(C#N)c(nc1Cl)C#N | 1g | 551283556
dichloropyrazine-2,3-dicarbonitrile | Pharmablock | 56413-95-7 | MFCD00191419 | 198.990 | C6Cl2N4 | 97.000 | Clc1nc(C#N)c(nc1Cl)C#N | 1g | 551283556
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eMolecules 13826-27-2 | 2,2'-Bi-1,3,2-benzodioxaborole | Accela ChemBio (ASD) | MFCD09842343 | 237.810 | C12H8B2O4 | 95.000 | O1B(Oc2ccccc12)B1Oc2ccccc2O1 | 10g | 517258232
2,2'-Bi-1,3,2-benzodioxaborole | Accela ChemBio (ASD) | 13826-27-2 | MFCD09842343 | 237.810 | C12H8B2O4 | 95.000 | O1B(Oc2ccccc12)B1Oc2ccccc2O1 | 10g | 517258232
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Medchemexpress LLC 1-(4-fluorophenyl)-N-[1-(2-methylsulfonylpyridin-4-yl)cyclopropyl]pyrazolo[3,4-c]pyridine-4-carboxamid | 1295298-26-8 | 98.9% | 10MM 1ML
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1-(4-fluorophenyl)-N-[1-(2-methylsulfonylpyridin-4-yl)cyclopropyl]pyrazolo[3,4-c]pyridine-4-carboxamid | 1295298-26-8 | 98.9% | 10MM 1ML
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Research Products International Corp 4-Chloro-1-Naphthol, 25 Grams
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- CAS Numbers: 604-44-4
- Molecular Formula: C10H7OCl
- Molecular Weight: 178.61
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eMolecules 13826-27-2 | 2,2'-Bi-1,3,2-benzodioxaborole | Accela ChemBio (ASD) | MFCD09842343 | 237.810 | C12H8B2O4 | 95.000 | O1B(Oc2ccccc12)B1Oc2ccccc2O1 | 25g | 517258233
2,2'-Bi-1,3,2-benzodioxaborole | Accela ChemBio (ASD) | 13826-27-2 | MFCD09842343 | 237.810 | C12H8B2O4 | 95.000 | O1B(Oc2ccccc12)B1Oc2ccccc2O1 | 25g | 517258233
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Medchemexpress LLC Melevodopa hydrochloride | 1421-65-4 | MFCD00038958 | 99.76% | 247.68 | 100 MG
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Melevodopa hydrochloride is an effervescent Levodopa prodrug. Levodopa is an orally active metabolic precursor of neurotransmitters dopamine and has anti-allodynic effects and the potential for Parkinson's disease.
- Effervescent prodrug of Levodopa
- Orally active metabolic precursor of dopamine
- Anti-allodynic effects
- Potential for Parkinson's disease treatment
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000723901 NERAMEXANE HYDROCHL 25MG
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Medchemexpress LLC N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo... | 2523016-96-6 | 99.9% | 876.97 g/mol | C47H53FN8O8 | 5 MG
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SK-575 is a proteolysis-targeting chimera (PROTAC) that selectively induces degradation of PARP1 and is used in biochemical and cellular research to study PARP1 biology and cancer cell responses.
- Potent PARP1 degrader with reported IC50 2.30 nM.
- High purity (99.86%).
- Molecular weight 876.97 g/mol.
- Molecular formula C47H53FN8O8.
- Soluble in DMSO at ~80 mg/mL; ultrasonic assistance recommended.
- Supplied in small research quantities (for example, 5 mg).
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Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 25 MG
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BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. It has potential for the treatment of poorly controlled asthma.
- Highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2).
- IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively.
- Potential for the treatment of poorly controlled asthma.
- Solid appearance, white to off-white color.
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eMolecules 57683-71-3 | Methyl 2-(aminosulfonyl)benzoate | Combi-Blocks | MFCD00009808 | 215.220 | C8H9NO4S | 95.000 | COC(=O)c1ccccc1S(N)(=O)=O | 25g | 495744660
Methyl 2-(aminosulfonyl)benzoate | Combi-Blocks | 57683-71-3 | MFCD00009808 | 215.220 | C8H9NO4S | 95.000 | COC(=O)c1ccccc1S(N)(=O)=O | 25g | 495744660
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Aobchem AOBCHEM
5000872551 2-PHENYL-2- 2-PROPEN-1-YL -1 3
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