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Filtered Search Results
Medchemexpress LLC Adrenalone hydrochloride | 62-13-5 | 99.88% | 500 MG
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Adrenalone hydrochloride is an adrenergic agonist employed as a topical vasoconstrictor and hemostatic. It acts as an inhibitor of dopamine β oxidase and exhibits chemical similarity to known norepinephrine transporter (NET) ligands, with an IC50 of 36.9 μM. It is a keton form of the natural substrate epinephrine and also inhibits substrate transport by NET. It is used for research purposes only.
- Acts as an adrenergic agonist
- Functions as a topical vasoconstrictor
- Exhibits hemostatic properties
- Inhibits dopamine β oxidase
- Chemically similar to norepinephrine transporter (NET) ligands
- Available as a solid, light yellow to yellow in appearance
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Medchemexpress LLC SARS-CoV-2 S protein receptor-binding domain, biotinylated (Omicron B.1.1.529) | 96.0% | 10 UG
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SARS-CoV-2 S protein receptor-binding domain, biotinylated (Omicron B.1.1.529), expressed in HEK293 cells with C-terminal Avi and His tags. Supplied as a 10 μg aliquot for research use; the certificate of analysis reports 96% purity by reducing SDS-PAGE.
- Biotinylated at Avi tag for site-specific immobilization.
- Expressed in mammalian cells for native glycosylation.
- C-terminal His tag for facile purification and detection.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Suitable for ELISA, SPR, BLI, and antibody binding studies.
- Supplied in a stable formulation for storage and handling.
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Medchemexpress LLC Milveterol (hydrochloride) | 804518-03-4 | 98.2% | C25H30ClN3O4 | 100 MG
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Milveterol hydrochloride is a long-acting β2-adrenergic receptor agonist. It can be used in the study of asthma and chronic obstructive pulmonary disease (COPD).
- Long-acting β2-adrenergic receptor agonist
- Suitable for asthma research
- Suitable for chronic obstructive pulmonary disease (COPD) research
- Bronchodilator
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Medchemexpress LLC Tetrahydrofolic acid | 135-16-0 | C19H23N7O6 | 100 MG
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Tetrahydrofolic acid is the biologically active vitamin B9 folate derivative. It acts as a donor of one-carbon groups for amino acids, nucleic acids, and lipids, and serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid.
- Functions as an endogenous metabolite
- Induces cytotoxicity in Adh5- and Fanconi anemia (FA)-deficient cells
- Promotes FANCD2 and ser139-H2AX focus formation in Adh5-/- cells
- Activates the DNA damage response
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Ambeed AMBEED
5000846864 5 7-DICHLORO-1 6-NAPHTH 1G
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Ambeed Bicyclo 2.2.2 octane1 4dicarbo
Bicyclo[2.2.2]octane-1,4-dicarboxylic acid, 711-02-4, 96%
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Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 500 MG
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Loperamide hydrochloride is an opioid receptor agonist and a selective human intestinal carboxylesterases (hiCE) inhibitor, known for its anti-diarrheal effect. This compound has a molecular formula of C29H34Cl2N2O2 and a molecular weight of 513.50. It is intended for research use only and has not been fully validated for medical applications.
- Opioid receptor agonist
- Selective and competitive human intestinal carboxylesterases inhibitor
- Demonstrates anti-diarrheal properties
- Induces ER stress and autophagy in certain cell lines (in vitro)
- Decreases specific protein lipidation levels in ATF4 KO cells (in vitro)
- Suitable for laboratory research purposes
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Medchemexpress LLC Thiobis-beta-Galactose-propyne | 1989627-40-8 | 25 MG
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The product is a reagent intended solely for testing and research purposes. It is not to be used as pharmaceuticals, food, or household goods. If used for purposes other than testing and research, no warranty is provided. For uses other than testing and research or as a raw material, inquiries should be directed to the sales department. For pharmaceutical raw materials, the product is sold to manufacturers as raw materials for dedicated pharmaceutical products and pharmaceutical additives. A confirmation document is required for the purchase of dedicated pharmaceutical products (those with "dedicated pharmaceutical" in the product name).
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Medchemexpress LLC (6S)-Tetrahydrofolic acid | 71963-69-4 | C19H23N7O6 | 50 MG
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(6S)-Tetrahydrofolic acid is an endogenous metabolite that is significantly more active than its (6R) form. It promotes the binding of fluorodeoxyuridylate to thymidylate synthase and acts as a growth factor for P. cerevisiae. This compound also exhibits a low affinity and high dissociation rate for folate-binding protein.
- Significantly more active than (6R) form
- Promotes binding of fluorodeoxyuridylate to thymidylate synthase
- Acts as a growth factor for P. cerevisiae
- Exhibits low affinity and high dissociation rate for folate-binding protein
- Endogenous metabolite with a molecular weight of 445.43
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784737 NAPHTHALENE-1 4-DICA 500G
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Ambeed 2 2 2Trifluoro1 4methoxyphenyl
2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone, 711-38-6, 97%
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Medchemexpress LLC BI 2536 | 755038-02-9 | 99.9% | 50 MG
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BI 2536 is a dual inhibitor targeting both PLK1 (Polo-like Kinase 1) and BRD4 (Bromodomain-containing protein 4), with IC50 values of 0.83 nM and 25 nM, respectively. It suppresses IFNB (Interferon-beta) gene transcription and exhibits antiproliferative activity against various human cancer cell lines. This product is intended for research use only.
- Targets PLK1 and BRD4
- High potency (IC50 of 0.83 nM for PLK1 and 25 nM for BRD4)
- Suppresses IFNB gene transcription
- Demonstrated antiproliferative activity against a wide range of human cancer cell lines
- Available in solid form and as a 10 mM solution in DMSO
- Purity of 99.9%
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Medchemexpress LLC BI-3812 | 2166387-64-8 | 99.3% | 558.03 | 100 MG
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BI-3812 is a chemical probe and a highly efficient BCL6 inhibitor. It suppresses the BTB domain of BCL6 with an IC50 value of ≤ 3 nM, demonstrating antitumor activity. This product is intended for research use only and not for patient use.
- Highly efficient BCL6 inhibitor
- Suppresses the BTB domain of BCL6 with an IC50 value of ≤ 3 nM
- Exhibits antitumor activity
- Cellular BCL6 IC50 of 40 nM
- Available as a chemical probe
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Medchemexpress LLC Cinaciguat hydrochloride | 646995-35-9 | 98.9% | C36H40ClNO5 | 100 MG
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Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator. It exhibits an EC50 of 15 nM in platelets, making it a valuable tool for studying guanylate cyclase pathways and related biological activities.
- Potent guanylate cyclase activator
- Effective at nanomolar concentrations in platelets
- Store solid at 4°C in a sealed container, away from moisture
- Store solutions at -80°C for up to 6 months or -20°C for up to 1 month, sealed and away from moisture
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eMolecules 39627-84-4 | Ambeed | 2-Naphthohydrazide | 250mg | 600832462 | A176952 | MFCD00016810 | 186.214 | C11H10N2O
Ambeed | Potassium trifluoro(propyl)borate | 1g | 650570098 | A189910 | 897067-94-6 | MFCD09992883 | 149.990 | C3H7BF3K
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