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Filtered Search Results
Medchemexpress LLC CRA-026440 hydrochloride | 847459-98-7 | 98.1% | 456.92 | 1 ML
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CRA-026440 hydrochloride is a potent, broad-spectrum Histone Deacetylase (HDAC) inhibitor. It exhibits antitumor and antiangiogenic activities. This compound also functions as a click chemistry reagent, containing an alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- Potent, broad-spectrum HDAC inhibitor
- Exhibits antitumor and antiangiogenic activities
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Shows antiproliferative effect on HUVEC endothelial cells
- Inhibits tumor cell growth and induces apoptosis
- Inhibits ex vivo angiogenesis
- Reduces tumor growth in xenograft models
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Medchemexpress LLC 4-Hydroxy-2-naphthoic acid | 1573-91-7 | 99.7% | 188.18 | 250 MG
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4-Hydroxy-2-naphthoic acid is a drug intermediate used for the synthesis of various active compounds. This product is for research use only and not sold to patients.
- Used for synthesis of various active compounds
- For research use only
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Medchemexpress LLC Glesatinib hydrochloride | 2319837-80-2 | 98.01% | 656.17 | 100 MG
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Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. This tyrosine kinase inhibitor also antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC). It is intended for research use only and not for patient use.
- Orally active
- Potent MET/SMO dual inhibitor
- Tyrosine kinase inhibitor
- Antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC)
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eMolecules 881658-92-0 | 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE | MFCD09027616 | 1g
WuXi ChemSupply | 8-BROMO-2-METHOXY-1,5-NAPHTHYRIDINE | 1g | 599165525 | LN00187622 | 95.000 | 881658-92-0 | MFCD09027616 | 239.072 | C9H7BrN2O
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Chemscene CHEMSCENE
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5000579746 2-NAPHTHOL 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703253 BI-69A11 10MG
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Chemscene ChemScene | 6-Hydroxy-1-naphthoic acid | 5G | CS-W016818 | 0.98 | 2437-17-4| MFCD00209983 | 188.18
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ChemScene | 6-Hydroxy-1-naphthoic acid | 5G | CS-W016818 | 0.98 | 2437-17-4| MFCD00209983 | 188.18
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428526 BI-27 SUPPLEMENT 50 10ML
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Apexbio Technology LLC Adapalene 106685-40-9 50mg
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Adapalene (106685-40-9) is a small-molecule agonist targeting retinoic acid receptor subtypes RAR and RAR with lower affinity for RAR and minimal activity toward RXR It is designed to selectively modulate retinoic acid receptor-mediated gene transcription thereby regulating cellular growth differentiation and apoptosis Adapalene exerts its biological activity primarily through selective activation of RAR and RAR subtypes In experimental models adapalene exhibits agonistic activity with Ki values of 2 3 nM for RAR 9 3 nM for RAR and 22 nM for RAR Based on these pharmacological properties adapalene holds research potential in investigating retinoid signaling pathways cellular proliferation apoptosis and antitumor mechanisms particularly in colorectal cancer models
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eMolecules 135-07-9 | Medchem Express | Methyclothiazide | 10mg | 527573895 | HY-B0562 | MFCD00242610 | 360.22 | C9H11Cl2N3O4S2
ChemScene | 2-(Propylamino)ethanol | 10g | 569146232 | CS-0105782 | 16369-21-4 | MFCD00002844 | 103.165 | C5H13NO
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(CCCC)C1=CCCCO1 | 250mg | 525924748](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502450967.PNG-250.jpg)
eMolecules 109669-45-6 | Tributyl(5,6-dihydro-4H-pyran-2-yl)stannane | Synthonix - Stock373.168 | C17H34OSn | 95.000 | CCCC[Sn](CCCC)(CCCC)C1=CCCCO1 | 250mg | 525924748
Tributyl(5,6-dihydro-4H-pyran-2-yl)stannane | Synthonix - Stock | 109669-45-6373.168 | C17H34OSn | 95.000 | CCCC[Sn](CCCC)(CCCC)C1=CCCCO1 | 250mg | 525924748
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Aobchem AOBCHEM
5000865297 1-IODO-4-METHOXYNAPHTHALENE 1G
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Aobchem AOBCHEM
5000865324 1-IODO-4-METHOXYNAPHTHALENE 5G
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Ambeed AMBEED
5000868094 1-AMINO-2-NAPHTHOIC ACID 1GR
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Apexbio Technology LLC BI-7273 1883429-21-7 5mg
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BI-7273 (CAS 1883429-21-7) is a selective small-molecule inhibitor targeting the bromodomains of BRD9 and BRD7 with reported IC50 values of 19 nM and 117 nM respectively BRD9 is a component of the SWI/SNF chromatin remodeling complex implicated in the proliferation of acute myeloid leukemia (AML) cells BI-7273 demonstrates effective disruption of BRD9 function in vitro and also engages BRD7 due to high sequence homology between their bromodomains Biochemical assays indicate negligible activity against BET family bromodomains even at high concentrations In vivo oral administration in mouse models shows dose-dependent systemic exposure BI-7273 is currently utilized as a chemical probe in preclinical studies investigating BRD9/BRD7 modulation in hematological malignancies
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