Unsubstituted Phenols
Medchemexpress LLC Cl2-SN-38 | 1036969-20-6 | 99.2% | 1627.79 | C82H106N12O23 | 5 MG
CL2-SN-38 is a cleavable linker-based SN-38 conjugate intended as a payload for antibody-drug conjugate (ADC) research. It enables targeted delivery of the topoisomerase I inhibitor SN-38 by conjugation to antibodies such as the anti-Trop-2 humanized antibody hRS7, and is suitable for in vitro and in vivo cancer research, ADC development, and linker stability studies.
- Cleavable linker enabling controlled payload release.
- Contains the topoisomerase I inhibitor SN-38 as the cytotoxic payload.
- Designed for conjugation to antibodies for ADC development.
- High purity (>99%) suitable for preclinical research.
- Available in multiple small-scale quantities for laboratory use.
Medchemexpress LLC CL2-SN-38 | 1036969-20-6 | 99.2% | 1627.79 | C82H106N12O23 | 100 MG
CL2-SN-38 is a cleavable linker-SN-38 conjugate intended for antibody-drug conjugate research. The molecule delivers the topoisomerase I inhibitor SN-38 linked by a cleavable spacer designed to release the active payload after antibody-mediated internalization. The product is supplied as a high-purity research reagent with documented solubility and storage recommendations.
- Provides SN-38 payload for ADC development.
- Features a cleavable linker for intracellular release.
- Suitable for conjugation to antibodies targeting tumor antigens.
- High purity for reproducible research results.
- Soluble in DMSO at high concentration; in vivo formulations documented.
- Supplied in small mg-scale quantities for laboratory use.
Medchemexpress LLC Cl2-sn-38 | 1036969-20-6 | 99.2% | 1627.79 | C82H106N12O23 | 50 MG
CL2-SN-38 is a cleavable linker-SN-38 agent-linker conjugate intended for antibody-drug conjugate (ADC) research. It is used to deliver the cytotoxic SN-38 payload to target cells via antibody targeting of cell-surface antigens; intracellular processing releases the active toxin, enabling targeted cancer research applications. Provided data include chemical composition, molecular weight, purity, storage, and solubility guidance.
- Cleavable linker-SN-38 conjugate for ADC research.
- Designed to conjugate with Trop-2-targeting antibodies.
- High purity suitable for research applications.
- Soluble in DMSO at high concentrations with ultrasonic assistance.
- Storage guidelines provided for solid and solution forms to maintain stability.
- Intended for targeted cancer research using ADC methodologies.
Medchemexpress LLC (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) | 158932-33-3 | 10 MG
(R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of secoisolariciresinol diglucoside found in flaxseed. It exhibits antioxidant and free radical scavenging activities and possesses DNA-radioprotective properties. It also inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cycles in inflammatory cells.
- Minor isomer found in flaxseed
- Exhibits antioxidant and free radical scavenging activities
- Possesses DNA-radioprotective properties
- Inhibits myeloperoxidase (MPO) activity
- Suppresses peroxidase and chlorination cycles in inflammatory cells
- Shows antiproliferative activity against human HCT-116 cells
Medchemexpress LLC (R,R)-Secoisolariciresinol diglucoside | 158932-33-3 | 20 MG
(R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside found in flaxseed. It possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cycles in inflammatory cells.