Saturated hydrocarbons
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 50 MG
I-287 is an orally active, selective PAR2 inhibitor that functions as a negative allosteric regulator of Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant (CFA)-induced inflammation in mice and is suitable for inflammation/immunology research.
- Selectively targets Gαq and Gα12/13 signaling
- Inhibits PAR2-mediated activation of proteins without impacting βarrestin2 recruitment or receptor internalization
- Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells
- Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells
- Reduces inflammation in C57BL/6J mice
Selleck Chemical LLC MD-224
MD-224 is a highly potent and effective degrader of the Human murine double minute 2 (MDM2) protein the main cellular inhibitor of the tumor suppressor p53 It strongly inhibits cell growth in leukemia cell lines with wild-type p53 and induces complete and lasting tumor regression in the RS4 11 xenograft tumor model
Medchemexpress LLC MD-224 10mM | 10MM 1ML
MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept MD-224 consists of ligands for Cereblon and MDM2 MD-224 induces rapid degradation of MDM2 at concentrations 1 nM in human leukemia cells and achieves an IC50 value of 1 5 nM in inhibition of growth of RS4 11 cells MD-224 has the potential to be a new class of anticancer agent[1] MD-224 is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
eMolecules 1,5-BIS(BENZYLOXY)PENTANE | 53150-24-6 | MFCD30490548 | 1g
AstaTech | 1,5-BIS(BENZYLOXY)PENTANE | 1g | 385237171 | AB10215 | 95.000 | 53150-24-6 | MFCD30490548 | 284.399 | C19H24O2
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eMolecules Building Block Tool
Medchemexpress LLC Tridecane | 629-50-5 | 99.5% | 184.36 g/mol | C13H28 | 25 G
Tridecane is an analytical standard of the C13 aliphatic hydrocarbon tridecane, supplied for research and analytical applications such as chromatographic reference and calibration.
- Analytical standard for chromatographic reference and calibration.
- High purity: 99.51% (GC).
- Low water content: 0.02% (KF).
- Chemical formula: C13H28.
- Molecular weight: 184.36 g/mol.
eMolecules AA Blocks LLC Cyclopentane-1 2-dione 100mg 795063316 AA00380L 0 000 3008-40-0 MFCD00045446 98 101 C5H6O2
AA Blocks LLC Cyclopentane-1 2-dione 100mg 795063316 AA00380L 0 000 3008-40-0 MFCD00045446 98 101 C5H6O2
Medchemexpress LLC 2-Methylcyclopentane-1,3-dione | 765-69-5 | MFCD00001406 | 100.0% | 112.13 | 100 G
2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids. It is intended for research use only and not for sale to patients.
- Key intermediate for total synthesis of steroids
- For research use only
- Molecular weight: 112.13
- Purity: 99.96%
- CAS number: 765-69-5
- Appearance: Solid
- Color: White to light yellow
Cambridge Isotope Laboratories 2 2 4-TriBDE (BDE-17) (unlabeled) 50 ug/mL in nonane 1 2 mL
2 2 4-TriBDE (BDE-17) (unlabeled) 50 ug/mL in nonane 1 2 mL
Medchemexpress LLC Dodecane-1,12-diol-d24 | 1219802-88-6 | MFCD08705053 | 99.0% | 226.48 g/mol | C12H2D24O2 | 5 MG
Dodecane-1,12-diol-d24 is the deuterium-labeled analogue of dodecane-1,12-diol provided as a stable-isotope reagent for research applications. It is intended for use as an internal standard, tracer, or isotopically labeled building block in analytical chemistry and synthetic workflows.
- High isotopic enrichment suitable for mass spectrometry and NMR studies.
- High chemical purity (99%) for reproducible analytical results.
- White to off-white solid, easy to handle and weigh.
- Soluble in common organic solvents for sample preparation and synthesis.
- Available in small, accurately quantified quantities for method development.
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 100 MG
I-287 | 2014368-93-3 | 99.4% | 565.04 | 100 MG
TARGETMOL CHEMICALS INC 9-hydroxy Stearic Acid 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 uM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 uM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase. Purity 99.7%
eMolecules ChemScene / 1-Methylcyclopentane-1-carboxylic acid / 100mg / 686121767 / CS-0135257 / 0.000 / 5217-05-0 / MFCD08444320 / 128.171 / C7H12O2
ChemScene / 1-Methylcyclopentane-1-carboxylic acid / 100mg / 686121767 / CS-0135257 / 0.000 / 5217-05-0 / MFCD08444320 / 128.171 / C7H12O2
Medchemexpress LLC Dodecane-1,12-diol | 5675-51-4 | MFCD00004755 | 99.2% | 202.34 g/mol | C12H26O2 | 50 G
Dodecane-1,12-diol (dodecamethylene glycol) is a linear C12 diol used as a chemical building block and biochemical reagent. It is commonly employed in the synthesis of polyesters and other polymers, and in enzymatic reactions for producing bio-based materials. The compound is supplied as a solid with high purity suitable for research and laboratory use.
- Linear C12 diol useful as a monomer in polymer synthesis.
- Supports enzymatic synthesis of bio-based polyesters.
- High purity suitable for research applications.
- Solid form with molecular formula C12H26O2 and MW 202.34 g/mol.
- Available in multiple laboratory package sizes, including 50 g.