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Filtered Search Results
Medchemexpress LLC 2-BUTYNE-1 4-DIOIC A 50G
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2-BUTYNE-1 4-DIOIC A 50G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000281738 BUTYNE-DOTA-TRIS T-B 250MG
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Medchemexpress LLC 18 111-CIS PC 10 mg
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18 111-CIS PC 10MG
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Medchemexpress LLC VE-821 | 1232410-49-9 | 99.7% | 368.41 | 50 MG
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VE-821 is a potent ATP-competitive inhibitor of ATR, with Ki/IC50 values of 13 nM/26 nM. It demonstrates excellent selectivity for ATR, showing minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ.
- Shows minimal cross-reactivity against related PIKKs ATM, DNA-PK, mTOR, and PI3Kγ
- Significantly enhances the sensitivity of PSN-1, MiaPaCa-2, and primary PancM pancreatic cancer cells to radiation and Gemcitabine
- ATR inhibition by VE-821 leads to inhibition of radiation-induced G2/M arrest in cancer cells
- Inhibits phosphorylation of Chk1 (Ser 345) in PSN-1 and MiaPaCa-2 cells after treatment with Gemcitabine, radiation, or both
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Medchemexpress LLC 5-phenyl-1-pentyne (pent-4-ynylbenzene) | 1823-14-9 | MFCD00039813 | 98.0% | 144.21 g·mol⁻¹ | C11H12 | 500 MG
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5-Phenyl-1-pentyne is a terminal alkyne used as a building block and intermediate in organic synthesis and medicinal chemistry research. It is supplied as a high-purity small-molecule suitable for laboratory applications.
- High purity: 98.0%.
- CAS number: 1823-14-9.
- Chemical formula C11H12; molecular weight 144.21 g·mol⁻¹.
- Provided in milligram and gram pack sizes for research use.
- SMILES identifier available for structure confirmation.
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Medchemexpress LLC Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate | 1049004-32-1 | 280.17 | 5 G
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Bpin-Cyclohexene-COOEt, also known as Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate, is a PROTAC linker belonging to the PEG class. It is designed for use in the synthesis of PROTAC molecules. This compound is a colorless to light yellow liquid.
- Intended for research use only.
- Unstable in solutions, requiring freshly prepared solutions for optimal use.
- Molecular weight of 280.17.
- Purity of 97.0%.
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Medchemexpress LLC 5-phenyl-1-pentyne | 1823-14-9 | MFCD00039813 | 98.0% | 144.21 g/mol | C11H12 | 250 MG
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5-Phenyl-1-pentyne is an aromatic alkyne used as an intermediate in organic synthesis and is reported to have antibacterial and antitumor activity. It is commonly used to assemble more complex molecules and to support medicinal chemistry research and structure-activity relationship studies.
- High purity suitable for research applications.
- Available in multiple pack sizes for lab use.
- Used as a reaction intermediate in synthetic chemistry.
- Supportive for medicinal chemistry and SAR studies.
- Identified by CAS and molecular data for clear substance identification.
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Medchemexpress LLC Ethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)acetate | 1166829-70-4 | >97.0% | 294.19 | C16H27BO4 | 500 MG
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Bpin-Cyclohexene-C-COOEt is a boron-pinacol substituted cyclohexene ethyl acetate used as a PROTAC linker in medicinal chemistry and targeted protein degradation research. The compound is supplied for research use only and is reported to have high purity and defined molecular characteristics.
- used as a PROtac linker in targeted protein degradation research.
- molecular formula: C16H27BO4.
- molecular weight: 294.19 g/mol.
- high purity (>97.0%).
- suitable for synthesis of SMARCA2/4 degrader scaffolds and related intermediates.
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Medchemexpress LLC Bpin-Cyclohexene-COOEt, CAS [[1049004-32-1]] | 1049004-32-1 | 280.17 | 10 G
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Bpin-Cyclohexene-COOEt (Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate) is a PROTAC linker belonging to the PEG class. It can be used to synthesize PROTAC molecules.
- PROTAC linker
- Belongs to the PEG class
- Used to synthesize PROTAC molecules
- Molecular weight: 280.17
- Purity: 97.78
- Reference compound
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Aldlab Chemicals LLC DIPHENYLPHOSPHINO FERROCENE
(2R)-1-[(4S)-4,5-Dihydro-4-phenyl-2-oxazolyl]-2-(diphenylphosphino)ferrocene
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![Medchemexpress LLC 2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl- | 1232410-49-9 | 99.7% | 368.41 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000365548-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl- | 1232410-49-9 | 99.7% | 368.41 | 10 MG
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VE-821 is a potent ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM. It demonstrates excellent selectivity for ATR with minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ. This compound enhances the sensitivity of pancreatic cancer cells to radiation and Gemcitabine, and inhibits radiation-induced G2/M arrest in cancer cells.
- Potent ATP-competitive inhibitor of ATR
- Excellent selectivity for ATR with minimal cross-reactivity
- Enhances sensitivity of pancreatic cancer cells to radiation and Gemcitabine
- Inhibits radiation-induced G2/M arrest in cancer cells
- Inhibits phosphorylation of Chk1 (Ser 345)
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Strem, An Ascensus Company Manganocene 98% 1g
CAS# 73138-26-8. 1g. Bis(cyclopentadienyl)manganese, 98+% (Manganocene). MFCD00045468. Molecular Weight: 185.13. Molecular Formula: (C5H5)2Mn. Color/form: brown xtl. Strem# 25-0200. http://www.strem.com/catalog/v/25-0200/
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Aqua Solutions 1-OCTENE IN SOLVENT ISOPAR E
Aqua Solutions 10% w/w 1-octene in Solvent (Isopar E) (600G)
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Aqua Solutions 1-OCTENE IN ISOOCTANE 1L
Aqua Solutions 25% v/v 1-octene in Isooctane (1L)
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Medchemexpress LLC Butyne-DOTA-tris(t-butyl ester) | 2125661-54-1 | 98.5% | 623.82 | C32H57N5O7 | 50 MG
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Butyne-DOTA-tris(t-butyl ester) is a bifunctional chelator and macrocyclic DOTA derivative used for bioconjugation and tumor pre-targeting research. It contains tert-butyl protected carboxylate arms and a terminal butyne handle that enables click-style conjugation to peptides, proteins, or targeting vectors, facilitating subsequent radiolabeling or imaging workflows. The material is supplied as a white to off-white solid with high reported purity and recommended cold storage for long-term stability.
- Bifunctional chelator suitable for bioconjugation
- Terminal alkyne handle enables click chemistry conjugation
- Tert-butyl protected carboxylates improve stability during synthesis
- High purity suitable for radiolabeling workflows
- Available in multiple pack sizes for research needs
- Recommended cold storage to preserve integrity
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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