Unsaturated hydrocarbons
- (3)
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- (112)
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- (162)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (1)
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- (3)
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- (2)
- (3)
- (3)
- (1)
- (2)
- (4)
- (4)
- (9)
- (23)
- (12)
- (8)
- (2)
- (38)
- (3)
- (16)
- (3)
- (5)
- (2)
- (23)
- (26)
- (2)
- (11)
- (43)
- (40)
- (1)
- (1)
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- (24)
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- (25)
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- (1)
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- (154)
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- (1)
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- (3)
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- (147)
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- (6)
- (2)
- (82)
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- (1)
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Filtered Search Results
Aobchem 2-Bromo-4-tricyclo[3 3 1 13 7]dec-1-ylbenzenamine | 95% | CAS 1459-52-5 | C16H20BrN | 500mg
2-Bromo-4-tricyclo[3 3 1 13 7]dec-1-ylbenzenamine | 95% | CAS 1459-52-5 | C16H20BrN | 500mg
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Aobchem B-(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)boronic acid | ≥97% | CAS 459423-32-6 | C17H23BO3 | 250mg
B-(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)boronic acid | ≥97% | CAS 459423-32-6 | C17H23BO3 | 250mg
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Aobchem 2-Bromo-4-tricyclo[3 3 1 13 7]dec-1-ylbenzenamine | 95% | CAS 1459-52-5 | C16H20BrN | 1g
2-Bromo-4-tricyclo[3 3 1 13 7]dec-1-ylbenzenamine | 95% | CAS 1459-52-5 | C16H20BrN | 1g
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Sigma Aldrich Fine Chemicals Biosciences 1,2-Dihydronaphthalene 98% | 447-53-0 | MFCD00001672 | 1G
1,2-Dihydronaphthalene 98% | Purity: 98% | Mol Wt: 130.19 | 447-53-0 | MFCD00001672 | 1G
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Aobchem AOBCHEM
5000940844 METHYL 4-TRICYCLO 3.3.1.13 7 D
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Medchemexpress LLC BQR-695 | 1513879-21-4 | 99.9% | 352.39 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BQR-695 is a PI4KIIIβ inhibitor effective against both human and Plasmodium variant PI4KIIIβ. This compound is for research use only, shows no toxicity to mature red blood cells, and induces a schizont-stage arrest.
- Has an IC50 of 80 nM for human PI4KIIIβ.
- Has an IC50 of 3.5 nM for the Plasmodium variant of PI4KIIIβ.
- Induces schizont-stage arrest.
- Exhibits cross-resistance with imidazopyrazine-resistant lines.
- Causes GFP-PHOsh2 redistribution to the parasite plasma membrane, indicating PI4P depletion.
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Sigma Aldrich Fine Chemicals Biosciences Allylcyclohexane | 2114-42-3 | MFCD00013769 | 25g
Allylcyclohexane | Purity: 96% | Mol Wt: 124.22 | 2114-42-3 | MFCD00013769 | 25g
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Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl]amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 nM for human PI4KIIIβ and 3.5 nM for the Plasmodium variant of PI4KIIIβ. Treatment with 0.5 μM causes GFP-PHOsh2 to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function. This inhibitor shows no evidence of toxicity against mature red blood cells (RBCs), induces a schizont-stage arrest, and exhibits cross-resistance with imidazopyrazine-resistant lines.
- Potent PI4KIIIβ inhibitor
- Effective against human and Plasmodium PI4KIIIβ variants
- Induces schizont-stage arrest
- No toxicity against mature red blood cells
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem B-(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)boronic acid | ≥97% | CAS 459423-32-6 | C17H23BO3 | 5g
B-(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)boronic acid | ≥97% | CAS 459423-32-6 | C17H23BO3 | 5g
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Pfaltz & Bauer VINYLCYCLOHEXANE 99% 5G
Vinylcyclohexane 99% 5G CAS# 695-12-5
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Aobchem B-(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)boronic acid | ≥97% | CAS 459423-32-6 | C17H23BO3 | 500mg
B-(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)boronic acid | ≥97% | CAS 459423-32-6 | C17H23BO3 | 500mg
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Aobchem Phenanthren-9-ol | ≥95% | CAS 484-17-3 | C14H10O | 5g
Phenanthren-9-ol | ≥95% | CAS 484-17-3 | C14H10O | 5g
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Aobchem 4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 1g
4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 1g
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Aobchem 4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 250mg
4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 250mg
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Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
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BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 nM for human PI4KIIIβ and 3.5 nM for the *Plasmodium* variant of PI4KIIIβ. For research use only.
- Treatment with 0.5 μM of either KAI407 or BQR695 causes GFP-PHOsh2 to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function.
- BQR695 shows no evidence of toxicity against mature red blood cells (RBCs).
- It induces a schizont-stage arrest indistinguishable from that observed in imidazopyrazine-treated parasites and exhibits cross-resistance with the imidazopyrazine-resistant lines.
- DMSO: 50 mg/mL (141.89 mM; requires ultrasonic; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO).
- Powder: -20°C for 3 years, 4°C for 2 years.
- In solvent: -80°C for 2 years, -20°C for 1 year.
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