Alpha-halocarboxylic acids and derivatives
Medchemexpress LLC Hyaluronic acid sodium (MW 200-1560) | 9067-32-7 | >99.41% | 5 MG
Hyaluronic acid sodium (MW 200-1560) | 9067-32-7 | >99.41% | 5 MG
Medchemexpress LLC Acetic acid, 2-iodo-, 1,1'-anhydride | 54907-61-8 | MFCD00001080 | 70.0% | 353.88 g·mol-1 | C4H4I2O3 | 100 MG
Iodoacetic anhydride is the 2-iodo derivative of acetic anhydride used as a reagent in chemical synthesis and biochemical research. It is supplied as a brown to dark brown solid with molecular formula C4H4I2O3 and molecular weight 353.88 g·mol-1.
- Molecular formula: C4H4I2O3
- Molecular weight: 353.88 g·mol-1
- Appearance: Brown to dark brown solid
- Cas number: 54907-61-8
- Typical pack size: 100 MG
- Purity (batch example): 70.0% (NMR)
Cayman Chemical SHU9119 trifluoroacetate sal
An MC1R agonist and MC4R antagonist (IC50s = 1.2 and 2.9 nM, respectively, for displacement of melanocortin); induces cAMP formation in HEK293 cells expressing human MC1R (EC50 = 1.11 nM), but inhibits cAMP formation in cells expressing human MC4R; increases food intake, body weight, fat mass, and lean mass, with concomitant increases in blood glucose, insulin, and leptin levels via disrupted melanocortin signaling in rats (24 nmol, i.c.v. per day for seven days); increases in body weight and fat mass in mice
Cayman Chemical W146 trifluoroacetate salt
An S1P1 receptor antagonist (Ki = 77 nM); selective for S1P1 over S1P2, S1P3, and S1P5 (Kis = >10 µM); prevents ligand-induced receptor internalization in CHO cells and inhibits ERK and Akt phosphorylation at 10 µM; increases AMD3100-induced KSL-HSPC entrance into mouse blood circulation from the bone marrow at 5 mg/kg in combination with AMD3100; disrupts the endothelial barrier and induces PMN neutrophil infiltration into the lungs and skin in an ovalbumin-induced mouse model of immune cell-mediated vascular injury at 10 UG intranasally or intradermally
Sigma Aldrich Fine Chemicals Biosciences Bromoacetic acid-2-13C 99 atom % 13C | 64891-77-6 | MFCD00002681 | 1G
Bromoacetic acid-2-13C 99 atom % 13C | Purity: 99% (CP) | Mol Wt: 139.94 | 64891-77-6 | MFCD00002681 | 1G
Cayman Chemical GGTI 298 trifluoroacetate sa
A CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I; arrests human tumor cells (IC50 = 10 µM for A549 cells) in G0/G1 and induces apoptosis by inhibiting proteasome activity and up-regulating the expression of the cyclin-dependent kinase inhibitor p21
eMolecules Chem-Impex Sodium azide 2 5kg 112439593 00278 0 000 26628-22-8 MFCD00003536 65 011 N3Na
Chem-Impex Sodium azide 2 5kg 112439593 00278 0 000 26628-22-8 MFCD00003536 65 011 N3Na
Cayman Chemical UFP101 trifluoroacetate salt
A synthetic peptide and nociceptin receptor antagonist (Ki = 0.06 nM in CHO cells expressing the human receptor); selective for the nociceptin receptor over the κ-opioid receptor (Ki = 204 nM in CHO cells expressing the rat receptor); inhibits GTPγS release from the nociceptin receptor expressed in CHO cell membranes (EC50 = 1.86 nM); increases the latency to tail withdrawal in the tail-flick test in mice at 10 nmol/animal, i.c.v.; increases survival in a mouse model of sepsis induced by cecal ligation and puncture at 0.003, 0.03, and 0.3 mg/kg
Cayman Chemical Apamin trifluoroacetate salt
An inhibitor of KCa2.2/SK2 channels (IC50s = 0.06-0.4 nM); selective for KCa2.2/SK2 channels over KCa2.1/SK1 and KCa2.3/SK3 channels (IC50s = 1-12 and 1-13 nM, respectively), as well as KCa3.1/SK4 channels at 1 µM but does inhibit Kv1.3 (IC50 = 13 nM); reduces CD8+ cell infiltration into the CNS and EAE severity, as well as increases peripheral blood levels of CD62L-, CD44L-, and CD44+ memory T cells, in mice; has commonly been used to determine the role of KCa/SK channels in various cells and tissues
Cayman Chemical FTI276 trifluoroacetate salt
A peptidomimetic inhibitor of FTase (IC50 = 500 pM); selective for FTase over GGTase I (IC50 = 50 nM); inhibits the growth of NIH3T3 cells expressing RasF at 20 µM; reduces tumor growth in a mouse xenograft model using Calu-1 cells that contain a K-Ras oncogenic mutation
Cayman Chemical W140 trifluoroacetate salt
An inactive enantiomer of W146; binds weakly to S1P1 (Ki = 4.6 µM for the human receptor); has been used as a negative control in the study of S1P1 receptor signaling
Selleck Chemical LLC LIT-001 trifluoroacetate
LIT-001 trifluoroacetate(LIT-001 TFA) is the first nonpeptide oxytocin receptor (OXTR) agonist that improves social interaction in a mouse model of autism