Boronic acid derivatives
Cayman Chemical CAY10591, Purity: ≥98%, CAS: 839699-72-8, 25 mg
An activator of SIRT1 that decreases TNF-α levels from 325 pg/ml (control) to 104 and 53 pg/ml at 20 and 60 µM, respectively; exhibits a significant dose-dependent effect on fat mobilization in differentiated adipocytes
Cayman Chemical 8 9EpETE Fatty Acids and Deriv
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo
Cayman Chemical 17 SHDHA Fatty Acids and Deriv
A hydroxy fatty acid formed from DHA by 15-LO and is a precursor to 17(S)-resolvins; inhibits platelet 12-LO (IC50 = 0.4 μM); inhibits TNF-α-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM); inhibits NLRP3 inflammasome formation induced by homocysteine in podocytes at 100 nM
Cayman Chemical CAY10573, Purity: ≥98%, CAS: 853652-40-1, 10 mg
A PPAR agonist that displays potent binding at PPARα, γ, and δ (IC50s = 113, 50, 223 nM, respectively) and potently transactivates PPARα, γ, and δ (EC50s = 8, 70, 500 nM, respectively); demonstrates stronger binding and functional activity for PPARγ than rosiglitazone
Cayman Chemical KT 5720 Inhibitors
A potent inhibitor of PKA; blocks PKA signaling through competitive inhibition of ATP (Ki = 60 nM); inhibits phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β
Chem-Impex International, Inc. 2-Methylphenylboronic acid | 16419-60-6 | MFCD00093526 | 5G
2-Methylphenylboronic acid, 16419-60-6, MFCD00093526, 5G
Chem-Impex International, Inc. 2-Methylphenylboronic acid | 16419-60-6 | MFCD00093526 | 25G
2-Methylphenylboronic acid, 16419-60-6, MFCD00093526, 25G
Cayman Chemical 17 SHDHA Fatty Acids and Deriv
A hydroxy fatty acid formed from DHA by 15-LO and is a precursor to 17(S)-resolvins; inhibits platelet 12-LO (IC50 = 0.4 μM); inhibits TNF-α-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM); inhibits NLRP3 inflammasome formation induced by homocysteine in podocytes at 100 nM
Cayman Chemical 17 RHDHA Fatty Acids and Deriv
An aspirin-induced DHA metabolite; a precursor to resolvins; inhibits TNF-α-induced IL-1β expression in human glioma cells
Aobchem 4-Carboxy-2-nitrophenylboronic acid | ≥97% | CAS 85107-54-6 | C7H6BNO6 | 10g
4-Carboxy-2-nitrophenylboronic acid | ≥97% | CAS 85107-54-6 | C7H6BNO6 | 10g
Aobchem 4-(2 2 2-Trifluoroethoxy)benzaldehyde | ≥97% | CAS 76579-46-9 | C9H7F3O2 | 500mg
4-(2 2 2-Trifluoroethoxy)benzaldehyde | ≥97% | CAS 76579-46-9 | C9H7F3O2 | 500mg
Aobchem 4-(2 2 2-Trifluoroethoxy)benzonitrile | ≥97% | CAS 56935-76-3 | C9H6F3NO | 1g
4-(2 2 2-Trifluoroethoxy)benzonitrile | ≥97% | CAS 56935-76-3 | C9H6F3NO | 1g
Aobchem 2-Bromo-5-methoxyphenylboronic acid | ≥97% | CAS 89694-44-0 | C7H8BBrO3 | 10g
2-Bromo-5-methoxyphenylboronic acid | ≥97% | CAS 89694-44-0 | C7H8BBrO3 | 10g