Boronic acid derivatives
Cayman Chemical CAY10462, Purity: ≥98%, CAS: 502656-68-0, 1 mg
A selective inhibitor of the 20-HETE synthase CYP4A11 (IC50 = 8.8 nM in human renal microsomes); 200-fold less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes
Aobchem Pyrimidine-5-boronic acid, AOBCHEM USA 10286-25G. 109299-78-7. MFCD03002366
Pyrimidine-5-boronic acid, AOBCHEM USA 10286-25G. 109299-78-7. MFCD03002366
Cayman Chemical CAY10434, Purity: ≥98%, CAS: 769917-29-5, 50 mg
A selective inhibitor of the 20-HETE synthase CYP4A11 (IC50 = 8.8 nM human renal microsomes)
Cayman Chemical CAY10499, Purity: ≥98%, CAS: 359714-55-9, 5 mg
A non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively); inhibits ATGL, DAGLa, ABHD6, and CES1 at 5 mM; inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 µM, respectively); reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats
Cayman Chemical CAY10455 Fatty Acids and Deriv
A fluorescent substrate for AEA transport; cleavage by intracellular esterases gives a bright fluorescence at 530 nm
Cayman Chemical 17 SHETE Fatty Acids and Deriv
A potent inhibitor of proximal tubule ATPase activity; is a CYP450 metabolite of arachidonic acid; inhibits proximal tubule ATPase activity by 70% at 2 µM
Cayman Chemical CAY10455 Fatty Acids and Deriv
A fluorescent substrate for AEA transport; cleavage by intracellular esterases gives a bright fluorescence at 530 nm