Organic phosphoric acids and derivatives
Medchemexpress LLC Uzansertib phosphate | 2088852-47-3 | 99.5% | 611.51 | C26H29F3N5O7P | 1 ML
Uzansertib phosphate is the phosphate salt of a small-molecule kinase inhibitor, provided for research use. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid quantities, and is used in preclinical studies investigating PIM kinase-related pathways and anticancer activity.
- Phosphate salt form for improved aqueous compatibility.
- Supplied as 10 mM solution in DMSO (1 mL) and as solid sizes for flexibility.
- High reported purity (~99.5%).
- Molecular weight 611.51; chemical formula C26H29F3N5O7P.
- Intended for laboratory research applications only.
![Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate | 438542-15-5 | 98.0% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231760.png-250.jpg)
Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate | 438542-15-5 | 98.0% | 1 ML
GW274150 phosphate is the phosphate salt form of a selective inducible nitric oxide synthase (iNOS) inhibitor supplied for research use. It is provided as a 10 mM solution (1 mL) or as solid materials, and is accompanied by a datasheet, certificate of analysis, and safety data sheet.
- White to off-white solid or clear aqueous solution.
- Purity 98.0%.
- Molecular weight 317.30 g/mol.
- Chemical formula C8H20N3O6PS.
- Available as 10 mM 1 mL solution or in solid sizes (5 mg-100 mg, larger quantities by quote).
- Solubility: water 100 mg/mL; PBS 12.5 mg/mL (may require ultrasonic and warming).
- Storage: store solids at 4°C under inert gas; in solvent store at -80°C (6 months) or -20°C (1 month).
- For research use only; not for human use.
Medchemexpress LLC Trisodium phosphate (dodecahydrate) | 10101-89-0 | 98.1% | 380.18 g/mol | Na3PO4.12H2O | 500 G
Trisodium phosphate dodecahydrate is an inorganic reagent used as a pH regulator, buffer, and corrosion inhibitor in laboratory and pharmaceutical applications. It is supplied as a white to off-white solid with high water content in the dodecahydrate form.
- High purity reagent for analytical and preparative use.
- Acts as a buffer and pH adjuster in aqueous solutions.
- Used as a corrosion inhibitor in electrochemical studies.
- Solid, white to off-white crystals suitable for handling and storage.
- Available in multiple pack sizes including 500 g.
TARGETMOL CHEMICALS INC KN-93 PHOSPHATE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II with K i of 370 nM. KN-93 phosphate inhibits serum-induced fibroblast cell growth in a comparable dose-dependent fashion to its inhibition of CaMK-II activity. purity: 99%
Medchemexpress LLC Pyridoxal 5'-phosphate (hydrate) | 853645-22-4 | 99.8% | 247.14 | 10 G
Pyridoxal phosphate, also known as Pyridoxal 5′-phosphate, is the active form of vitamin B6 and an endogenous metabolite. It acts as an inhibitor of reverse transcriptases and is used for the treatment of tardive dyskinesia. Its biological activity includes inhibition of DNA Polymerase, RNase H, and NEIL2, as well as the proliferation of SK-OV-3 and OVCAR-3 cancer cells. In vivo, it alleviates memory impairment in mouse models and inhibits the formation of advanced glycation end-products (AGEs) in rat diabetes models.
- Appearance: Off-white to light yellow solid
- Purity (HPLC): 99.76%
- Storage (solid): 4°C, sealed, away from moisture
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month (sealed, away from moisture)
Medchemexpress LLC Carvedilol phosphate hemihydrate | 610309-89-2 | 99.9% | C24H26N2O4.H3PO4.1/2H2O | 500 MG
Carvedilol phosphate hemihydrate is a non-selective β/α-1 blocker. This multiple action antihypertensive agent has potential use in angina and congestive heart failure.
- Inhibits lipid peroxidation with an IC50 of 5 μM.
- Autophagy inducer.
- Inhibits the NLRP3 inflammasome.
Medchemexpress LLC Triciribine phosphate | 00-00-0 | ≥99.0% | 400.28 g/mol | C13H17N6O7P | 5 MG
Triciribine phosphate is the phosphorylated form of triciribine and is supplied as a purified small-molecule reagent for biochemical and cellular research. It is used to modulate signaling pathways, including inhibition of AKT phosphorylation, and may affect nucleotide synthesis pathways. Refer to the manufacturer's product page and safety data sheet for handling, storage, and safety information.
- Inhibits AKT phosphorylation and related signaling pathways.
- High purity suitable for biochemical and cellular assays.
- Provided as a solid for dissolution in common laboratory solvents.
- Available in milligram-scale pack sizes for laboratory use.
- Intended for research use only; not for human therapeutic use.
Alkali Scientific Pyridoxal 5 Phosphate Monohydrate, 5 Grams
Pyridoxal 5 Phosphate Monohydrate is a derivative of vitamin B6 that serves as an essential cofactor in numerous enzyme reactions within biochemical pathways. The 5-gram quantity of this reagent is ideal for small-scale research in enzyme catalysis and metabolic studies. Pyridoxal 5 phosphate is involved in amino acid metabolism, neurotransmitter synthesis, and the production of hemoglobin. It is also critical in studies investigating enzymatic reactions in pharmaceutical research and clinical diagnostics. As a high-purity reagent, it is commonly used in laboratories for research on vitamin B6-dependent enzymes, offering reliable results in studies related to human health and disease treatment.
Medchemexpress LLC Diethyl 2-bromoglutarate | 7209-00-9 | 91.01% | 267.12 | 1 G
Diethyl 2-bromoglutarate is a drug intermediate used for the synthesis of various active compounds. It is supplied as a colorless to light yellow liquid.
- Used in the synthesis of active compounds
- Appears as a colorless to light yellow liquid
Medchemexpress LLC Diethyl mesoxalate | 609-09-6 | MFCD00009121 | 99.5% | 174.15 g/mol | C7H10O5 | 100 G
Diethyl mesoxalate is the diethyl ester of mesoxalic (oxomalonic) acid and is used as a synthetic building block and biochemical reagent in organic chemistry and life-science research. It is commonly employed in condensation and malonate chemistry to prepare heterocycles and functionalized intermediates; consult the SDS for handling and storage recommendations.
- High chemical purity for reliable reaction outcomes.
- Useful building block for synthesis of heterocycles and malonates.
- Soluble in common organic solvents, facilitating reaction setup.
- Known molecular weight and formula aid stoichiometric planning.
- Suitable for research and development applications.
Alkali Scientific 1 Naphthyl Phosphate Monosodium Salt Monohydrate, 5 G
Naphthyl Phosphate Monosodium Salt Monohydrate (5g) is a high-purity enzyme substrate used for detecting phosphatase activity in various biochemical applications. When the substrate is hydrolyzed by phosphatase enzymes, it releases a colored product that can be measured spectrophotometrically. This compound is commonly used in enzyme assays to study enzyme kinetics and activity. The 5g package is suitable for large-scale experiments and multiple applications in research. It is ideal for use in biochemical, molecular biology, and clinical research labs that require precise substrate reactions for enzyme analysis.
Apexbio Technology LLC Oseltamivir phosphate 204255-11-8 10mM (in 1mL DMSO)
Oseltamivir phosphate known pharmacologically as GS-4104 functions as a selective competitive inhibitor targeting neuraminidase an enzyme essential for influenza viral particle release from infected cells By inhibiting neuraminidase activity this compound restricts influenza viral propagation within host cells Oseltamivir phosphate demonstrates inhibitory activity against influenza A and B viruses with reported neuraminidase inhibitory potency (IC50) typically in the low nanomolar range ( 1 5 nM) In biomedical research it is primarily utilized to evaluate antiviral efficacy investigate neuraminidase-inhibition mechanisms and facilitate influenza infection modeling in preclinical experimental systems and drug screening assays
Apexbio Technology LLC KN-92 phosphate 1135280-28-2 50mg
KN-92 phosphate is a small-molecule analog of the Ca2 /calmodulin-dependent kinase II (CaMKII) inhibitor KN-93 It is designed as an inactive control compound to distinguish CaMKII-specific effects in experimental settings KN-92 phosphate does not inhibit CaMKII activity and thus serves as a negative control for CaMKII inhibition studies Additionally KN-92 phosphate blocks certain voltage-gated potassium (Kv) channels such as Kv1 2 and Kv1 5 reducing steady-state current amplitudes upon depolarization Based on these pharmacological properties KN-92 phosphate holds research potential in investigating mechanisms underlying CaMKII-related signaling pathways and Kv channel functions
Medchemexpress LLC Pyridoxal 5'-phosphate hydrate | 853645-22-4 | 99.8% | 247.14 | 1 MG
Pyridoxal 5'-phosphate hydrate is the active form of vitamin B6 and an essential cofactor for various enzymes, including aromatic l-amino acid decarboxylase, which produces the neurotransmitters dopamine and serotonin. It is the most significant coenzyme variant in the intracellular phosphorylation of vitamin B6 and can be interconverted with other variants like pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).
- Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression.
- Inhibits the proliferation of cancer cells.
- Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
- Inhibits the formation of advanced glycation end-products (AGEs).
- Prevents the progression of diabetic nephropathy.