Organic phosphoric acids and derivatives
Medchemexpress LLC ODN 2216 | 332437-00-0 | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G) | 5 MG
ODN 2216 is a human-specific Toll-like Receptor 9 (TLR9) ligand or agonist. It is known to induce high amounts of IFN-α and IFN-β, and IFN-α by plasmacytoid DC (pDC) and IL-12 (p40) production by dendritic cells (DC). It also stimulates IFN-γ production in peripheral blood mononuclear cells (PBMC), which is an indirect effect mediated by IFN-α/β. ODN 2216 can activate NK cells and promote IFN-γ production of TCR-triggered CD4+ T cells and is intended for research use only.
- Induces high amounts of IFN-α and IFN-β
- Stimulates IFN-γ production in peripheral blood mononuclear cells
- Activates NK cells
- Promotes IFN-γ production of TCR-triggered CD4+ T cells
Medchemexpress LLC Uzansertib phosphate | 2088852-47-3 | 98.0% | 611.51 g/mol | C26H29F3N5O7P | 5 MG
Uzansertib phosphate is the phosphate salt of uzansertib, an ATP-competitive pan-PIM kinase inhibitor used in preclinical research. It inhibits PIM1, PIM2, and PIM3 and shows antiproliferative activity in hematologic cancer cell lines. Supplied as a solid for research use only.
- Potent inhibition of PIM1, PIM2, and PIM3 (reported IC50s: PIM1 0.24 nM, PIM2 30 nM, PIM3 0.12 nM).
- Phosphate salt improves aqueous properties versus the free base.
- Suitable for in vitro and in vivo studies of PIM kinase signaling.
- Soluble in DMSO at high concentrations for assay formulation.
- Typical reported purity ≈98-99.5% depending on supplier.
![eMolecules 10049-21-5 | Sodium phosphate, monobasic, monohydrate | Chem-Impex | MFCD00149208 | 137.991 | H4NaO5P | 100.000 | O.[Na+].OP(O)([O-])=O | 250g | 272390509](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000216860.jpg-250.jpg)
eMolecules 10049-21-5 | Sodium phosphate, monobasic, monohydrate | Chem-Impex | MFCD00149208 | 137.991 | H4NaO5P | 100.000 | O.[Na+].OP(O)([O-])=O | 250g | 272390509
Sodium phosphate, monobasic, monohydrate | Chem-Impex | 10049-21-5 | MFCD00149208 | 137.991 | H4NaO5P | 100.000 | O.[Na+].OP(O)([O-])=O | 250g | 272390509
Medchemexpress LLC Phospho-Cyclin B1 (Ser126) Antibody (YA208) | 100 UL
Phospho-Cyclin B1 (Ser126) Antibody (YA208) is a Rabbit-derived and non-conjugated IgG monoclonal antibody that targets Phospho-Cyclin B1 (Ser126).
- Derived from domestic rabbit monoclonal (YA208)
- Reactive with human samples
- Applicable for western blot
- Applicable for immunoprecipitation
eMolecules 38399-13-2 | AstaTech | BIS(2-BROMOPHENYL)ACETYLENE | 0.25g | 448278747 | T70861 | 96 | MFCD00238712 | 336.026 | C14H8Br2
methyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethoxyphosphoryl)acetate | Pharma Block | 88568-95-0 | MFCD00043304 | 331.261 | C13H18NO7P | 97.000 | COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(OC)OC | 100g | 198734915
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Apexbio Technology LLC KN-93 Phosphate 1188890-41-6 5mg
KN-93 Phosphate (CAS 1188890-41-6) is a small-molecule inhibitor targeting calcium/calmodulin-dependent protein kinase II (CaMKII) It is designed to selectively inhibit CaMKII thereby modulating cellular proliferation survival neurotransmitter regulation and related signal transduction pathways KN-93 Phosphate exerts its biological activity primarily by competitively binding to Ca2 /calmodulin disrupting their interaction with CaMKII and preventing CaMKII activation and autophosphorylation In cell-based studies KN-93 Phosphate demonstrates inhibitory activity with IC50 values of 9 M for CaMKII monomer and 3 M for CaMKII dodecamer Experimental models include hepatic stellate cells and NIH 3T3 fibroblasts Based on these pharmacological properties KN-93 Phosphate holds research potential in the study of cell cycle regulation apoptosis neurotransmitter synthesis and neurodegenerative disorders particularly Parkinson s disease models
Medchemexpress LLC Fingolimod phosphate | 402615-91-2 | C19H34NO5P | 100 MG
Fingolimod phosphate is an orally active sphingosine 1-phosphate (S1P) receptor agonist. It promotes the neuroprotective effects of microglia and can be used for research of multiple sclerosis and neurologic diseases.
- Prevents lymphocytes from moving out of lymphoid organs.
- Inhibits autoreactive lymphocytes from infiltrating the central nervous system.
- Downregulates activated microglial production of pro-inflammatory cytokines such as tumor necrosis factor-a, interleukin-1β, and interleukin-6.
- Upregulates microglial production of brain-derived neurotrophic factor and glial cell-derived neurotrophic factor.
- Solid, white to off-white appearance.
- Purity of 99.18%.
- For research use only.
Medchemexpress LLC Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(phenylmethyl) ester | 108549-23-1 | ≥98.0% | 345.42 | 25 G
Dibenzyl diisopropylphosphoramidite is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It may be utilized for the preparation of phosphopeptides and is also employed in the synthesis of a GDP (guanosine diphosphate) analog, SML-8-73-1. Additionally, it is useful for nucleotide coupling.
- Biochemical reagent
- Can be used as a biological material or organic compound for life science related research
- May be used for the preparation of phosphopeptides
- Used for the synthesis of a GDP (guanosine diphosphate) analog, SML-8-73-1
- Useful for nucleotide coupling
eMolecules 1009-85-4 | Ambeed | 14-Bis(2-chloroethyl)piperazine | 1g | 490540710 | A236067 | MFCD01703917 | 211.13 | C8H16Cl2N2
ChemScene | 7-Bromochroman-4-amine | 100mg | 687373302 | CS-0321549 | 1016804-06-0 | MFCD09949875 | 228.089 | C9H10BrNO
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Apexbio Technology LLC KN-92 phosphate 1135280-28-2 10mM (in 1mL DMSO)
KN-92 phosphate is a small-molecule analog of the Ca2 /calmodulin-dependent kinase II (CaMKII) inhibitor KN-93 It is designed as an inactive control compound to distinguish CaMKII-specific effects in experimental settings KN-92 phosphate does not inhibit CaMKII activity and thus serves as a negative control for CaMKII inhibition studies Additionally KN-92 phosphate blocks certain voltage-gated potassium (Kv) channels such as Kv1 2 and Kv1 5 reducing steady-state current amplitudes upon depolarization Based on these pharmacological properties KN-92 phosphate holds research potential in investigating mechanisms underlying CaMKII-related signaling pathways and Kv channel functions
Selleck Chemical LLC Fludarabine Phosphate S1229-1g
Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis
Medchemexpress LLC (E)-KN-93 (phosphate) | 1188890-41-6 | MFCD03788201 | 99.9% | 599.03 g/mol | C26H32ClN2O8PS | 5 MG
(E)-KN-93 phosphate is a cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII). It disrupts Ca2+/CaM interaction with CaMKII and is supplied as a purified research reagent with analytical documentation for use in biochemical and cellular studies.
- High purity (99.85%).
- Water-soluble phosphate form for improved solubility.
- Suitable for biochemical and cellular assays.
- Provided with COA, HNMR, LCMS, and SDS documents.
- Molecular formula C26H32ClN2O8PS; molecular weight 599.03 g/mol.
- Available in small research pack sizes for laboratory use.
Selleck Chemical LLC Histamine Phosphate S4117-100mg
Histamine(Histamine diphosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors Histamine Phosphate can be used to induce animal models of Gastric and Intestinal Ulcers
eMolecules 65094-22-6 | Diethyl (Bromodifluoromethyl)phosphonate | Accela ChemBio (ASD) | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 100g | 444751349
Diethyl (Bromodifluoromethyl)phosphonate | Accela ChemBio (ASD) | 65094-22-6 | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 100g | 444751349
Medchemexpress LLC Uzansertib phosphate | 2088852-47-3 | 99.5% | 611.51 g/mol | C26H29F3N5O7P | 100 MG
Uzansertib phosphate is the phosphate salt of uzansertib, an orally active, ATP-competitive pan-PIM kinase inhibitor supplied as a white to off-white solid for research use. The compound is used in biochemical and cellular assays to investigate PIM kinase activity and JAK/STAT signaling.
- High purity (99.5%) suitable for research applications.
- Solid powder form, easy to weigh and store.
- Molecular formula C26H29F3N5O7P and molecular weight 611.51 g/mol.
- Used in biochemical kinase assays and cellular proliferation studies.
- Soluble in DMSO for assay preparation.