Organic phosphoric acids and derivatives
Apexbio Technology LLC Pyridoxal 5 phosphate 54-47-7 100mg
Pyridoxal 5-phosphate (CAS 54-47-7) is a biologically active derivative of vitamin B6 functioning primarily as a coenzyme in numerous enzymatic reactions It is designed to facilitate amino acid metabolism and biosynthesis pathways including neurotransmitter and sphingolipid synthesis as well as porphyrin biosynthesis Pyridoxal 5-phosphate exerts its biological activity primarily through coenzyme-mediated facilitation of transamination and other enzymatic transformations Its activity and affinity vary depending on the specific enzyme involved with reported enzyme IC50 values ranging broadly depending on enzyme type and experimental conditions Based on these pharmacological properties Pyridoxal 5-phosphate holds research potential in elucidating enzyme mechanisms metabolic pathway profiling assay optimization and the study of biosynthetic processes
Medchemexpress LLC Pyridoxal phosphate | 54-47-7 | 99.67% | 50 MG
Pyridoxal phosphate is the active form of vitamin B6. It acts as an inhibitor of reverse transcriptases and is used for the treatment of tardive dyskinesia.
- Target: Reverse transcriptase, endogenous metabolite, ERK, amyloid-β.
- Research areas: Neurological disease, metabolic disease, cancer.
- Category: Human gut microbiota metabolites, immune system disorder, microorganisms, ketones, aldehydes, acids, disease markers, endocrine diseases, nervous system disorder, endogenous metabolite.
- Available as an analytical standard for research and analytical applications.
- Available as a deuterium-labeled compound.
- Verification: 3 publications.
Apexbio Technology LLC Pyridoxal 5 phosphate 54-47-7 500mg
Pyridoxal 5-phosphate (CAS 54-47-7) is a biologically active derivative of vitamin B6 functioning primarily as a coenzyme in numerous enzymatic reactions It is designed to facilitate amino acid metabolism and biosynthesis pathways including neurotransmitter and sphingolipid synthesis as well as porphyrin biosynthesis Pyridoxal 5-phosphate exerts its biological activity primarily through coenzyme-mediated facilitation of transamination and other enzymatic transformations Its activity and affinity vary depending on the specific enzyme involved with reported enzyme IC50 values ranging broadly depending on enzyme type and experimental conditions Based on these pharmacological properties Pyridoxal 5-phosphate holds research potential in elucidating enzyme mechanisms metabolic pathway profiling assay optimization and the study of biosynthetic processes
Medchemexpress LLC Pyridoxal phosphate | 54-47-7 | 99.95% | 500 UG
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. This product is for research use only.
- Severely inhibits DNA Polymerase and RNase H, leading to an immediate reduction in DNA synthesis.
- Conjugation to pyridoxal phosphate fully inhibits NEIL2.
- Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression in HepG2 cells.
- Inhibits the proliferation of cancer cells SK-OV-3 and OVCAR-3.
- Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
- Inhibits the formation of advanced glycation end-products (AGEs) and prevents the progression of diabetic nephropathy.