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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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An OGA inhibitor (IC50 46 nM) selective for OGA overBhexosaminidase (IC50 >10 UM) and a panel of 277 kinases (IC50s >1 UM for all) increases the levels of O-GlcNAcylated proteins in SH-SY5Y cells (EC50 450 nM)
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Conduritol B epoxide is an irreversible covalent inhibitor of acid β-glucosidase (GCase) used to block GCase activity in biochemical and cellular studies. It is supplied in solid form and as a 10 mM solution in DMSO for convenient preparation and dosing in research assays.
Irreversible covalent inhibitor of acid β-glucosidase (GCase).
Useful for biochemical and cellular assays investigating lysosomal function.
Available as solid and as a 10 mM solution in DMSO for convenience.
High reported purity and defined molecular weight for reproducible results.
Stable under recommended storage conditions to preserve activity.
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