Azetidines
Medchemexpress LLC 1-Boc-azetidine-3-yl |25g
1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1] /sup
Medchemexpress LLC (R)-Azetidine-2-carboxylic acid | 7729-30-8 | MFCD00800731 | 99.6% | 101.10 g/mol | C4H7NO2 | 1 G
(R)-Azetidine-2-carboxylic acid is the R-enantiomer of azetidine-2-carboxylic acid, a nonproteinogenic amino acid used as an ADC linker and in biochemical research. The material is supplied as a solid for laboratory use.
- R-enantiomer of azetidine-2-carboxylic acid.
- Nonproteinogenic amino acid and ADC linker.
- Molecular formula C4H7NO2; molecular weight 101.10 g/mol.
- Purity reported as 99.6% (data sheet) and 99.9% (alternate listing).
- Appearance solid; store protected from light at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
- Available in small laboratory pack sizes for research use.
Accela Chembio Inc 3-hydroxyazetidine Hydrochloride | 25g | 18621-18-6 | MFCD02683887 | 95+% | Shelf Life: 900 Days | Light Sensitive/moisture Sensitive/nitrogen Or Argon/+4
3-hydroxyazetidine Hydrochloride | 25g | 18621-18-6 | MFCD02683887 | 95+% | Shelf Life: 900 Days | Light Sensitive/moisture Sensitive/nitrogen Or Argon/+4
Medchemexpress LLC 1-Cbz-azetidine-3-carboxylic acid | 97628-92-7 | MFCD09027504 | 99.6% | 235.24 | C12H13NO4 | 25 G
1-Cbz-azetidine-3-carboxylic acid is an N-protected azetidine carboxylic acid used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as an alkyl chain linker for PROTAC construction. It is supplied as a white to off-white solid with high purity suitable for medicinal chemistry and bioconjugation applications.
- non-cleavable ADC linker for antibody-drug conjugates
- alkyl chain-based PROTAC linker for targeted protein degradation
- high purity (99.6%) suitable for synthesis and conjugation
- soluble in DMSO at 100 mg/mL; may require ultrasonic
- stable as powder at -20°C for long-term storage, or 4°C for shorter term
Advanced Chemblocks Inc 2-THIASPIRO 3.3 HEPTAN-6-ONE1G
2-THIASPIRO[3.3]HEPTAN-6-ONE, 1523571-94-9, MFCD27987239
Medchemexpress LLC Ethyl azetidine-3-carboxylate hydrochloride | 405090-31-5 | 98.0% | 165.62 g/mol | C6H12ClNO2 | 5 G
Ethyl azetidine-3-carboxylate hydrochloride is the hydrochloride salt of ethyl azetidine-3-carboxylate, used as a synthetic building block in medicinal chemistry and antibody-drug conjugate linker synthesis.
- Hydrochloride salt supplied as a powder.
- Purity 98.0% (NMR).
- Molecular formula C6H12ClNO2 and molecular weight 165.62 g/mol.
- Available in laboratory-scale quantities, including 5 g packs.
- Recommended storage -20°C per certificate of analysis.