Azobenzenes
Medchemexpress LLC D5D-IN-326 | 1236767-85-3 | 99.9% | 473.27 | C17H11F8N3O4 | 5 MG
D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor (CAS 1236767-85-3) with reported nanomolar potency in enzymatic and cell-based assays and demonstrated activity in preclinical metabolic disease models. The compound is supplied for research use in multiple formats and sizes and is characterized by high purity and defined storage stability.
- Selective inhibitor of delta-5 desaturase with nanomolar potency.
- Reduces insulin resistance and body weight in preclinical models.
- High purity (99.9%) for reliable experimental results.
- Available as powder and solution formats for flexible dosing.
- Stable under recommended storage conditions for long-term use.
- Supplied in small research quantities suitable for in vitro and in vivo studies.
![eMolecules Ambeed / Methyl 3-amino-2-benzo[b]furancarboxylate / 250mg / 525177991 / A301059 / / 57805-85-3 / MFCD00466275 / 191.186 / C10H9NO3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502436930.JPG-250.jpg)
eMolecules Ambeed / Methyl 3-amino-2-benzo[b]furancarboxylate / 250mg / 525177991 / A301059 / / 57805-85-3 / MFCD00466275 / 191.186 / C10H9NO3
Ambeed / Methyl 3-amino-2-benzo[b]furancarboxylate / 250mg / 525177991 / A301059 / / 57805-85-3 / MFCD00466275 / 191.186 / C10H9NO3
eMolecules AstaTech / 3-(AMINOMETHYL)BENZAMIDE / 0.25g / 416218579 / Y10174 / 96.000 / 102562-86-7 / MFCD07186292 / 150.181 / C8H10N2O
AstaTech / 3-(AMINOMETHYL)BENZAMIDE / 0.25g / 416218579 / Y10174 / 96.000 / 102562-86-7 / MFCD07186292 / 150.181 / C8H10N2O
![eMolecules Medchem Express / Nacubactam / 5mg / 628192271 / HY-109008 / / 1452458-86-4 / [null] / 324.310 / C9H16N4O7S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502470772.JPG-250.jpg)
eMolecules Medchem Express / Nacubactam / 5mg / 628192271 / HY-109008 / / 1452458-86-4 / [null] / 324.310 / C9H16N4O7S
Medchem Express / Nacubactam / 5mg / 628192271 / HY-109008 / / 1452458-86-4 / [null] / 324.310 / C9H16N4O7S
Medchemexpress LLC Licarin A | 51020-86-1 | MFCD20260801 | 5 MG
Licarin A is a neolignan found in various plants, known for its anti-allergic and anti-inflammatory effects. It reduces TNF-α and PGD2 production by inhibiting PKCα/βII and p38 MAPK pathways.
- Significantly reduces TNF-α production in DNP-HSA-stimulated RBL-2H3 cells
- Exhibits anti-allergic effects
- Reduces PGD2 production and COX-2 expression
- Demonstrates anti-inflammatory effects
- Inhibits PKCα/βII and p38 MAPK pathways
- Found in plants like Aristolochia taliscana, Machilus thunbergii, and Myristica fragrans
Medchemexpress LLC Lupiwighteone | 104691-86-3 | 5 MG
Lupiwighteone is an isoflavone from wild-growing plants with antioxidant, antimicrobial, and anticancer properties. It induces apoptosis in human breast cancer cells by inhibiting the PI3K/Akt/mTOR pathway. For research use only.
- Antioxidant and antimicrobial effects.
- Anticancer properties: induces apoptosis in breast cancer cells by inhibiting PI3K/Akt/mTOR.
- Cytotoxicity against various cell lines (e.g., DU-145, SGC-7901).
- Induces cell cycle arrest and apoptosis in DU-145 cells.
- Dose-dependent reduction of cell cycle proteins (CDK1, 2, 4, 6, cyclinD1, B1) and increased ROS production.
- Activates mitochondria-based intrinsic apoptosis, up-regulating cytochrome c and caspase-3, and down-regulating p-Akt/Akt and VEGF.
Medchemexpress LLC Lys006 hydrochloride | 2619563-79-8 | 429.23 | 50 MG
LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 of 2 nM. It is extracted from patent WO2015092740A1, example 29, and is for research use only. It can be used for the research of inflammatory and autoimmune disorders.
- Potent inhibitor of LTA4H hydrolase
- IC50 of 2 nM
- Used for research on inflammatory and autoimmune disorders
- Currently in Phase 2 clinical trials for inflammatory acne, ulcerative colitis, hidradenitis suppurativa, and non-alcoholic fatty liver disease/nonalcoholic steatohepatitis
eMolecules 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid | 121219-20-3 | MFCD06656273 | 1g
Combi-Blocks | 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid | 1g | 117526294 | BB-9012 | 98.000 | 121219-20-3 | MFCD06656273 | 258.070 | C12H17BF2O3
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Medchemexpress LLC Valategrast (R-411 free base) | 220847-86-9 | 97.1% | C30H32Cl3N3O4 | 50 MG
Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. It is being investigated for its potential in treating Chronic Obstructive Pulmonary Disease (COPD) and asthma. It contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid binds to the metal ion in the metal-ion-dependent adhesion site (MIDAS).
- Potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist.
- Potential for treating Chronic Obstructive Pulmonary Disease (COPD).
- Potential for treating asthma.
- Contains an l-phenylalanine-N-aroyl motif for binding to the metal ion in the MIDAS site.
Medchemexpress LLC Ker047 (ALK2-IN-4) | 2248154-85-8 | 98.8% | 475.56 | 50 MG
KER047 (ALK2-IN-4) is a potent activin receptor-like kinase-2 (ALK2) inhibitor. It can be used for research into metabolic diseases such as fibrodysplasia ossificans progressiva (FOP).
- Potent activin receptor-like kinase-2 (ALK2) inhibitor.
- Used for research of metabolic disease, specifically fibrodysplasia ossificans progressiva (FOP).
Medchemexpress LLC Catalposide | 6736-85-2 | 5 MG
Catalposide is an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). It inhibits the production of TNF-α, IL-1β, and IL-6, and also suppresses NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages. It is intended for research use only.
- Purity of 98.0%
- Inhibits TNF-α, IL-1β, and IL-6 production
- Suppresses NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages
- Displays IC50 > 10 μM against human A2780, A549, BGC-823, Bel-7402, and HT-29 cells
- Isolated from Catalpa ovata G. Don (Bignoniaceae)
Medchemexpress LLC Catalposide | 6736-85-2 | MFCD28015867 | 1 MG
Catalposide is an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). It inhibits TNF-α, IL-1β, and IL-6 productions, and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages. This product is for research use only.
- Solid appearance
- White to yellow color
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC Valategrast (R-411 free base) | 220847-86-9 | 97.1% | C30H32Cl3N3O4 | 100 MG
Valategrast (R-411 free base) is a potent and orally active dual antagonist of integrin α4β1 (VLA-4) and α4β7, showing potential for treating Chronic Obstructive Pulmonary Disease (COPD) and asthma. It features a l-phenylalanine-N-aroyl motif, with its carboxylic acid binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS).
- CAS no.: 220847-86-9
- Molecular weight: 604.95
- Formula: C30H32Cl3N3O4
- Appearance: Off-white to light yellow solid
- Solubility: ≥ 4.25 mg/mL (7.03 mM) in various in vivo dissolution methods
- Storage: -80°C, stored under nitrogen
Medchemexpress LLC 2-Pyridinecarboxamide, 5-[[(6-chloro-2-pyridinyl)methyl](1-oxo-2-propen-1-yl)amino]-N-phenyl | 2305052-86-0 | 98.8% | C21H17ClN4O2 | 100 MG
BPK-25 is an active acrylamide that promotes the degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins through a post-translational mechanism involving covalent protein engagement. It also inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
- Promotes degradation of NuRD complex proteins.
- Inhibits TMEM173 activation.
- Active acrylamide.
- Intended for research and analytical applications.
Medchemexpress LLC PR5-LL-CM01 | 1005307-86-7 | 98.4% | 401.51 | 50 MG
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities and demonstrates efficacy in inhibiting cancer cells while showing low toxicity in normal cells.
- Has IC50 values ranging from 2-4 μM in PDAC cells (PANC1, MiaPaCa2, and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116, and DLD1).
- Strongly inhibits colony-forming ability in both PANC1 and HT29 cells.
- Inhibits NF-κB activation and its target gene expression in PDAC and CRC cells.
- Significantly decreases TNFα and IL8 expression in both PANC1 and HT29 cells (at 0-15 μM).
- Shows significant anti-tumor effects in PANC1 and HT29 xenografted mice in vivo (20 mg/kg; i.p.; 3 times per week) without visibly affecting their body weight.