Azobenzenes

eMolecules​ AstaTech / 15-DIHYDROXYPENTAN-3-ONE / 0.25g / 297085484 / 20750 / 95.000 / 4254-85-7 / MFCD06658431 / 118.132 / C5H10O3

AstaTech / 15-DIHYDROXYPENTAN-3-ONE / 0.25g / 297085484 / 20750 / 95.000 / 4254-85-7 / MFCD06658431 / 118.132 / C5H10O3

eMolecules​ Pharmablock / 2-aminopyrazolo[15-a]pyrimidine-3-carboxylic acid / 25mg / 736632784 / PBZ3170 / 0.000 / 1394003-86-1 / MFCD22543886 / 178.151 / C7H6N4O2

Pharmablock / 2-aminopyrazolo[15-a]pyrimidine-3-carboxylic acid / 25mg / 736632784 / PBZ3170 / 0.000 / 1394003-86-1 / MFCD22543886 / 178.151 / C7H6N4O2

Medchemexpress LLC 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine | 928853-86-5 | 98.5% | 313.42 | C16H19N5S | 100 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

4-MMPB (CAS 928853-86-5) is a small-molecule research compound that selectively inhibits 15-lipoxygenase and has been used in studies of cancer biology. It is provided as a high-purity research reagent with characterized activity and recommended storage conditions for long-term stability.

• Selective 15-lipoxygenase inhibitor with reported IC50 ≈ 18 μM.
• High purity suitable for research (≈98.5%).
• Available in small pack sizes for laboratory use, including solid and solution formats.
• Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (up to 6 months) or -20°C (up to 1 month).
• Molecular formula C16H19N5S and molecular weight 313.42, suitable for analytical characterization.

Medchemexpress LLC 4-MMPB | 928853-86-5 | 313.42 g/mol | C16H19N5S | 25 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

4-MMPB is a small-molecule research compound that acts as a selective 15-lipoxygenase inhibitor and is provided for laboratory research use only. It has documented enzyme inhibition and cell viability data and is commonly used in biochemical assays and exploratory cellular studies.

• Selective 15-lipoxygenase inhibition (IC50 ≈ 18 μM)
• Molecular formula C16H19N5S; molecular weight 313.42 g/mol
• Soluble in DMSO (7.69 mg/mL; may require sonication)
• Compatible in vivo formulations at ≥ 0.77 mg/mL in multiple vehicle systems
• Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years)
• Intended for laboratory research use only; not for human or clinical use

Medchemexpress LLC 4-MMPB | 928853-86-5 | 98.5% | 313.42 g/mol | C16H19N5S | 50 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

4-MMPB is a research reagent and selective 15-lipoxygenase inhibitor used in biochemical and pharmacological studies. Supplied as a solid with characterization data and supporting documents (COA, SDS), it is intended for research use only.

• Solid, light yellow to orange appearance
• Purity 98.5% (manufacturer reported)
• Molecular weight 313.42 g/mol, formula C16H19N5S
• Available in small milligram packages including 50 MG
• Includes datasheet, certificate of analysis, and SDS for characterization and safety
• Store powder at -20°C (3 years) or 4°C (2 years); in solvent store at -80°C or -20°C

Medchemexpress LLC PR5-LL-CM01 | 1005307-86-7 | 98.4% | 401.51 | 50 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities and demonstrates efficacy in inhibiting cancer cells while showing low toxicity in normal cells.

• Has IC50 values ranging from 2-4 μM in PDAC cells (PANC1, MiaPaCa2, and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116, and DLD1).
• Strongly inhibits colony-forming ability in both PANC1 and HT29 cells.
• Inhibits NF-κB activation and its target gene expression in PDAC and CRC cells.
• Significantly decreases TNFα and IL8 expression in both PANC1 and HT29 cells (at 0-15 μM).
• Shows significant anti-tumor effects in PANC1 and HT29 xenografted mice in vivo (20 mg/kg; i.p.; 3 times per week) without visibly affecting their body weight.