Benzoxadiazoles
Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 99.8% | 494.66 g/mol | C25H43NaO6S | 10MM 1ML
INT-767 is a research-grade dual farnesoid X receptor (FXR) and TGR5 agonist with reported mean EC50 values of 30 nM (FXR) and 630 nM (TGR5). It is supplied as a white to off-white solid and is available as a 10 mM solution in DMSO. Molecular formula C25H43NaO6S; molecular weight 494.66 g/mol. Intended for laboratory research use only.
- Potent dual FXR and TGR5 agonist with EC50s of 30 nM and 630 nM, respectively.
- High purity suitable for research applications.
- Available as solid or 10 mM DMSO solution for convenience.
- Highly soluble in DMSO and water according to manufacturer data.
- Stable under recommended storage: solid at 4°C; in solution at -80°C for long-term storage.
- Used in studies of bile acid signaling, metabolic disease, and liver injury models.
Sigma Aldrich Fine Chemicals Biosciences 7-Fluorobenzofurazan-4-sulfonic acid ammonium salt for HPLC derivatization, LiChropur(TM), >=98.5% (HPLC) | 84806-27-9 | MFCD02682109 | 25MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium salt for HPLC derivatization, LiChropur(TM), >=98.5% (HPLC) | Purity: >=98.5% (HPLC) | Mol Wt: 235.19 | 84806-27-9 | MFCD02682109 | 25MG
Accela Chembio Inc 4-benzofurazancarboxaldehyde | 1g | 32863-32-4 | MFCD07772900 | 97+% | Shelf Life: 1980 Days | Light Sensitive/air Sensitive/+4
4-benzofurazancarboxaldehyde | 1g | 32863-32-4 | MFCD07772900 | 97+% | Shelf Life: 1980 Days | Light Sensitive/air Sensitive/+4
Medchemexpress LLC Nbd-amine | 10199-91-4 | 96.7% | 100 MG
NBD-amine is a fluorogenic amine that fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments. It is used as an environment-sensitive fluorescent probe and labeling reagent in biochemical and biophysical research.
- Fluorogenic amine that increases fluorescence in nonpolar environments.
- Useful as a fluorescent probe and labeling reagent for biomolecules.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Available in multiple pack sizes, including 100 mg.
- Supplied with reported purity suitable for research applications.
Medchemexpress LLC Apelin-16, human, bovine acetate | 99.8% | 2010.37 (free base) | 5 MG
Apelin-16, human, bovine acetate is a biologically active peptide. Apelin is the endogenous ligand for the G-protein-coupled APJ receptor. It is produced as a pre-proprotein of 77 amino acids, and Apelin-16 is one of its active fragments.
- Biologically active peptide
- Endogenous ligand for the G-protein-coupled APJ receptor
- Derived from a pre-proprotein of 77 amino acids
- Active fragment of Apelin
Medchemexpress LLC 7-nitro-2,1,3-benzoxadiazol-4-ylamine | 10199-91-4 | 96.7% | 10 MG
NBD-amine (7-nitro-2,1,3-benzoxadiazol-4-ylamine) is a fluorogenic amine used as a fluorescent probe and a synthetic building block for labeling and sensing applications. It fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments. CAS 10199-91-4; purity ~96.7%.
- Fluorogenic amine that enhances fluorescence in hydrophobic environments.
- Useful for labeling, sensing, and probe development.
- Soluble in DMSO at 31.25 mg/mL; ultrasonic agitation may be needed.
- Powder stable at -20°C for up to 3 years.
- Molecular weight 180.12 g/mol; formula C6H4N4O3.
eMolecules Potassium benzofurazan-5-trifluoroborate | 1225608-24-1 | MFCD09800741 | 5g
Combi-Blocks | Potassium benzofurazan-5-trifluoroborate | 5g | 517033884 | QA-9729 | 95.000 | 1225608-24-1 | MFCD09800741 | 226.010 | C6H3BF3KN2O
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Medchemexpress LLC Nbd-556 | 333353-44-9 | 99.6% | C17H24ClN3O2 | 1 ML
NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. It demonstrates potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Potent HIV-1 entry inhibitor
- Blocks gp120-CD4 interaction
- Shows potent cell fusion and virus-cell fusion inhibitory activity
- Inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion
- Inhibits infection of MT-2 cells by laboratory-adapted HIV-1 strains
- Inhibits CD4-dependent virus in a dose-dependent manner
Apexbio Technology LLC NBD-Cl 10199-89-0 1g
NBD-Cl (10199-89-0) is a fluorescent labeling reagent that covalently reacts with nucleophilic groups specifically amines and thiols It is designed to derivatize these functional groups enabling detection through the formation of highly fluorescent conjugates NBD-Cl exerts its biological utility primarily through its electrophilic reaction mechanism with free amino and thiol groups in biomolecules No specific experimental model or quantitative activity metric is provided Based on these chemical properties NBD-Cl holds research potential in the labeling and detection of amino acid residues peptides proteins and thiol-containing enzymes as well as in studies of enzyme activities and biomolecular interactions
Medchemexpress LLC NBD-557 | 333352-59-3 | 99.4% | C17H24BrN3O2 | 50 MG
NBD-557 is a potential HIV-1 inhibitor, exhibiting potent cell fusion and virus-cell fusion inhibitory activity. This small molecule targets viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4, without affecting later stages of the HIV-1 life cycle like reverse transcriptase, integrase, or protease. It is active against both X4 and R5 viruses, and effective against HIV-1 laboratory-adapted strains, including an AZT-resistant strain, and HIV-1 primary isolates.
- Targets HIV-1 entry by inhibiting gp120 binding to CD4
- Does not inhibit reverse transcriptase, integrase, or protease
- Active against X4 and R5 viruses
- Effective against HIV-1 laboratory-adapted and primary isolates
- Binds to unliganded HIV-1 gp120
- For research use only