Benzoxadiazoles
Medchemexpress LLC 6α-ethyl-3α,7α,23-trihydroxy-24-nor-5β-cholan-23-sulfate | 1000403-03-1 | >98.0% | 494.66 g·mol⁻1 | C25H43NaO6S | 50MG
INT-767 is a synthetic dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5 (GPBAR1), used as a research reagent in preclinical studies of liver and metabolic disease. Reported activity includes mean EC50s of 30 nM (FXR) and 630 nM (TGR5); CAS 1000403-03-1; molecular formula C25H43NaO6S; molecular weight 494.66 g·mol⁻1. Typical supplier-reported purity is >98%. Material is for research use only and not for human therapeutic use.
- Dual FXR and TGR5 agonist for bile-acid signaling studies.
- Well-characterized potency: EC50 30 nM (FXR) and 630 nM (TGR5).
- High reported purity suitable for in vitro and in vivo experiments.
- Supplied as the sodium-sulfate derivative with defined molecular weight.
- Widely used in preclinical models of liver injury, steatosis, and metabolic regulation.
- For research use only; not for clinical or human use.
Medchemexpress LLC Nbd-amine | 10199-91-4 | 96.7% | 100 MG
NBD-amine is a fluorogenic amine that fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments. It is used as an environment-sensitive fluorescent probe and labeling reagent in biochemical and biophysical research.
- Fluorogenic amine that increases fluorescence in nonpolar environments.
- Useful as a fluorescent probe and labeling reagent for biomolecules.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Available in multiple pack sizes, including 100 mg.
- Supplied with reported purity suitable for research applications.
Medchemexpress LLC NBD-amine | 10199-91-4 | 96.7% | 50 MG
NBD-amine is a fluorogenic amine used as a fluorescent probe and reagent. It fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments, and is supplied as a powder with demonstrated solubility in DMSO.
- Fluorogenic amine that increases fluorescence in hydrophobic environments.
- CAS number 10199-91-4; molecular weight 180.12 g·mol⁻¹; formula C6H4N4O3.
- Purity 96.7% as supplied.
- Soluble in DMSO (≈31.25 mg/mL); hygroscopic DMSO affects solubility.
- Storage: powder -20°C (stable up to 3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in multiple package sizes including 50 MG.
Apexbio Technology LLC NBD-F 29270-56-2 50mg
NBD-F (29270-56-2) is a fluorescent derivatization reagent utilized for the detection and quantification of amino acids and low molecular weight amines NBD-F exerts its activity by selectively reacting with primary and secondary amines through its benzofurazan structure forming fluorescent conjugates detectable in biological samples Based on these properties NBD-F holds research potential in biochemical analysis metabolic profiling disease pathology investigation and fluorescent labeling in proteomics and molecular biology
AdipoGen NBD dodecanoic acid N-SE
Chemical. CAS 689263-76-1. Formula C22H29N5O7. MW 475.5. Synthetic. Suitable for probing the ligand binding sites of fatty acid and sterol carrier proteins as well as the investigation of lipolysis processes.
eMolecules Potassium benzofurazan-5-trifluoroborate | 1225608-24-1 | MFCD09800741 | 5g
Combi-Blocks | Potassium benzofurazan-5-trifluoroborate | 5g | 517033884 | QA-9729 | 95.000 | 1225608-24-1 | MFCD09800741 | 226.010 | C6H3BF3KN2O
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Apexbio Technology LLC NBD-F 29270-56-2 100mg
NBD-F (29270-56-2) is a fluorescent derivatization reagent utilized for the detection and quantification of amino acids and low molecular weight amines NBD-F exerts its activity by selectively reacting with primary and secondary amines through its benzofurazan structure forming fluorescent conjugates detectable in biological samples Based on these properties NBD-F holds research potential in biochemical analysis metabolic profiling disease pathology investigation and fluorescent labeling in proteomics and molecular biology
Medchemexpress LLC Ganglioside GQ1b (bovine) sodium | 68652-37-9 | >98.0% | 2508.5 g/mol | C106H178N6O55Na4 | 1mg
Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs[1]
Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 99.8% | 494.66 g/mol | C25H43NaO6S | 10MM 1ML
INT-767 is a research-grade dual farnesoid X receptor (FXR) and TGR5 agonist with reported mean EC50 values of 30 nM (FXR) and 630 nM (TGR5). It is supplied as a white to off-white solid and is available as a 10 mM solution in DMSO. Molecular formula C25H43NaO6S; molecular weight 494.66 g/mol. Intended for laboratory research use only.
- Potent dual FXR and TGR5 agonist with EC50s of 30 nM and 630 nM, respectively.
- High purity suitable for research applications.
- Available as solid or 10 mM DMSO solution for convenience.
- Highly soluble in DMSO and water according to manufacturer data.
- Stable under recommended storage: solid at 4°C; in solution at -80°C for long-term storage.
- Used in studies of bile acid signaling, metabolic disease, and liver injury models.
Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | C18H18F3N5O2S | 10MG
NBD-14270 is a pyridine-analog small molecule HIV-1 entry antagonist that binds gp120 and inhibits viral entry. Supplied for research use as a high-purity solid, it shows reported antiviral potency with low cytotoxicity.
- Purity 99.53% for consistent experimental results.
- High in vitro potency (IC50 ≈180 nM) against HIV-1 Env-pseudotyped viruses.
- Low cytotoxicity (CC50 >100 μM) supporting cellular assays.
- Soluble in DMSO (100 mg/mL) for ready stock solutions.
- Solid, yellow to brown appearance for easy handling and storage.
- Recommended storage: sealed, away from moisture and light; in solvent, -80°C (6 months) or -20°C (1 month).