Benzoxazines
TARGETMOL CHEMICALS INC MANAGLINAT DIALANETIL 5MG
Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. Managlinat dialanetil (MB06322) is an orally available and potent fructose 16-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes. purity: 98%
TARGETMOL CHEMICALS INC APRICITABINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 uM) the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase (alpha) (beta) and (gamma) with Ki values of 300 uM 12 uM and 112.25 uM respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients with good tolerability and low selective resistance. purity: 100%
TARGETMOL CHEMICALS INC RAC-WAY-161503 10MG
Also available in 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. (Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki 4 nM; EC50 12 nM) with anti-obesity and antidepressant effects. purity: 98%
TARGETMOL CHEMICALS INC TRPV4 AGONIST-1 FREE BAS 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM in the hTRPV4 Ca2+ assay). purity: 99%
TARGETMOL CHEMICALS INC OGERIN 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ogerin is a selective GPR68 positive allosteric modulator (pEC50 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki 220 nM) at A2A receptor and weak antagonist activity (Ki 736 nM) at 5-HT2B receptor. purity: 98%
TARGETMOL CHEMICALS INC FASUDIL 50MG
Also available in 5 mg 10 mg 25 mg 100 mg and bulk. Please contact Fisher for quotes. Fasudil (HA-1077) is a potent inhibitor of ROCK1 PKA PKC and MLCK. purity: 99%
TARGETMOL CHEMICALS INC RIMONABANT 50MG
Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue of effect is a reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U. Mexico and Brazil. It was rejected for approval for use in the United States. purity: 99%
TARGETMOL CHEMICALS INC YHO-13351 FREE BASE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YHO-13351 free base is the water-soluble prodrug of YHO-13177 which is an inhibitor of BCRP . purity: 100%
TARGETMOL CHEMICALS INC R-MG-132 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132. purity: 98%
TARGETMOL CHEMICALS INC CLINAFLOXACIN 50MG
Also available in 5 mg 10 mg 25 mg 100 mg and bulk. Please contact Fisher for quotes. Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic. purity: 97%
TARGETMOL CHEMICALS INC ISOORIENTIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Isoorientin (Homoorientin) has antioxidant activity. purity: 98%
TARGETMOL CHEMICALS INC DEL-22379 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 uM. purity: 99%
TARGETMOL CHEMICALS INC XL413 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent selective and ATP competitive inhibitor of Cdc7 with an IC 50 of 3.4 nM. XL413 hydrochloride also exhibits potent effect with IC 50 s of 215 42 nM on CK2 PIM1 respectively and an EC 50 of 118 nM on pMCM. purity: 99%
TARGETMOL CHEMICALS INC VALBENAZINE 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Valbenazine (NBI-98854) a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor is approved for the treatment of tardive dyskinesia. purity: 99%
TARGETMOL CHEMICALS INC OLMUTINIB 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Olmutinib (HM61713 BI 1482694) is an orally available small molecule a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form. purity: 99%