Benzoxazines
TARGETMOL CHEMICALS INC DC661 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DC661 is palmitoyl-protein thioesterase 1 (PPT1) inhibitor inhibits autophagy and acts as an anti-lysosomal agent. Anti-cancer activitypurity: 98%
Cell Signaling Technology beta-2-microglobulin (E8G2O) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
beta-2-microglobulin (E8G2O) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
TARGETMOL CHEMICALS INC FEZOLINETANT 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes. purity: 99%
Cell Signaling Technology Phospho-SLP-76 Ser376 E3G9U
Phospho-SLP-76 (Ser376) (E3G9U) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate) 100 ul
TARGETMOL CHEMICALS INC CREBANINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. 1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata. 2. Crebanine can also decrease the incidence of VF and CA by CaCl_2 in rats and by chloroform in mice but has no proteetive effects on ouahain-indueed arrhythmias in guinea pigs. 3. Crebanine has potential utility of crebanine in the development of neurodegenerative therapy might be used as the starting point to develop a drug for Alzheimer's disease. 4. Crebanine has anti-cancer activity can inhibit the proliferation of human leukemic cells (HL-6 U937 and K562) human fibrosarcoma cells (HT18) and cervix cancer cell lines (KB-3-1 and KB-V1; it mediates cell cycle arrest at G/G1 phase and this was associated with down-regulation of cyclins A and D. purity: 99%
TARGETMOL CHEMICALS INC LADUVIGLUSIB TRIHYDROCHL 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Laduviglusib trihydrochloride (CT99021 trihydrochloride) is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3(alpha) and GSK-3(beta). Laduviglusib trihydrochloride inhibits human GSK-3(beta) with a Ki of 9.8 nM. Laduviglusib trihydrochloride is an activator of Wnt/(beta)-catenin signaling. Laduviglusib trihydrochloride induces autophagy. purity: 99%
TARGETMOL CHEMICALS INC AG1024 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 uM) and is less potent for IR(IC50=57 uM). purity: 99%
TARGETMOL CHEMICALS INC PIMOBENDAN 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50 0.32 uM). purity: 99%
TARGETMOL CHEMICALS INC ARCYRIAFLAVIN A 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Arcyriaflavin A is a metabolite obtained from the fungi Nocardiopsis sp. purity: 97%
TARGETMOL CHEMICALS INC ALTENUSIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Altenusin is a natural nonsteroidal fungal metabolite as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 uM. purity: 98%
Aat Bioquest Cyanine 5 hydrazide [equivalent to Cy5 hydrazide]
A variety of cyanine 5 ( Cy5) dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis.
TARGETMOL CHEMICALS INC GSK572A 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK572A is a novel and potent potent inhibitor of EchA6 which can be used to treat tuberculosis. purity: 98%
TARGETMOL CHEMICALS INC SP2509 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM). purity: 99%
TARGETMOL CHEMICALS INC CORNUSIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-(kappa)B inhibition as well as the negative regulation of ERK1/2 p38 and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity and improvements in mitochondrial energy metabolism and antioxidant properties. purity: 99%
TARGETMOL CHEMICALS INC S3I-201 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50 86±33 uM) and low effect towards STAT1/5. purity: 99%