Benzoxazines
Cell Signaling Technology Whitlow/218 Linker (E3U7Q) Rabbit mAb (Alexa Fluor(R) 594 Conjugate) 100 ul
Whitlow/218 Linker (E3U7Q) Rabbit mAb (Alexa Fluor(R) 594 Conjugate) 100 ul
Cell Signaling Technology CD11c (D1V9Y) Rabbit mAb (Alexa Fluor(R) 555 Conjugate) 100 ul
CD11c (D1V9Y) Rabbit mAb (Alexa Fluor(R) 555 Conjugate) 100 ul
Amsbio LLC Luciferase (firefly) & CRE Expression cell line (GFP-Bsd)
Luciferase (firefly) & CRE Expression cell line (GFP-Bsd)
TARGETMOL CHEMICALS INC CORNUSIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-(kappa)B inhibition as well as the negative regulation of ERK1/2 p38 and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity and improvements in mitochondrial energy metabolism and antioxidant properties. purity: 99%
TARGETMOL CHEMICALS INC AM580 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AM580 (CD336) is a retinoic acid receptor agonist that is selective for RAR(alpha)( IC50 8 nM )purity: 99%
TARGETMOL CHEMICALS INC COMPSTATIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Compstatin a cyclic tridecapeptide which was originally discovered from phage-display libraries is a highly potent and selective C3 inhibitor. purity: 100%
TARGETMOL CHEMICALS INC DECURSIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects potentially by inhibiting the TGF-(beta)1 induced NOX activation and Smad signaling. 3. Decursin has anti-cancer activity mediated suppression of the PKC(alpha) MAPK and NF-(kappa)B pathways in MCF-7 cells. 4. Decursin exhibits cytotoxicity against various human cancer cells and to possess anti-amnesic activity in vivo through the inhibition of AChE activity. purity: 97%
TARGETMOL CHEMICALS INC ISOORIENTIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Isoorientin (Homoorientin) has antioxidant activity. purity: 98%
TARGETMOL CHEMICALS INC FA16 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. FA16 is a selective metabolically stable ferroptosis inducer with an IC50 value of 1.26 uM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system Xc-)-mediated exchange of intracellular glutamate for extracellular cystine.FA16 significantly inhibited tumor growth in a HepG2 xenograft tumor model. HepG2 xenograft tumor model significantly inhibited tumor growth.
Medchemexpress LLC Zilovertamab vedotin | 98.6% | 1 MG
Zilovertamab vedotin is an antibody-drug conjugate for preclinical cancer research that combines a humanized anti-ROR1 monoclonal antibody with the cytotoxic payload monomethyl vedotin. It is supplied as a lyophilized powder for experimental use.
- targets receptor tyrosine kinase-like orphan receptor 1 (ROR1)
- contains monomethyl vedotin cytotoxic payload
- suitable for in vitro and in vivo research
- high reported purity (98.61%)
- documentation available: certificate of analysis and safety data sheet
TARGETMOL CHEMICALS INC GEFITINIB-BASED PROTAC 3 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Gefitinib-based PROTAC 3 conjugating an EGFR binding element to a VHL ligand via a linker induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells respectively[1]. purity: 98%
TARGETMOL CHEMICALS INC NAPABUCASIN 50MG
Also available in 5 mg 10 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor. purity: 99%