Benzoxazines
TARGETMOL CHEMICALS INC PIMOBENDAN 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50 0.32 uM). purity: 99%
TARGETMOL CHEMICALS INC MK-3328 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. MK-3328 has a high affinity for (beta)-Amyloid (IC5010.5 nM) and can be used as a candidate PET ligand for clinical assessment of (beta)-amyloid plaque load. MK-3328 is a potential treatment for Alzheimer's disease. purity: 99%
TARGETMOL CHEMICALS INC CDK9-IN-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CDK9-IN-2 is a special CDK9 inhibitor extracted from patent WO/2012131594A1 (compound CDKI(8)) and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours) respectively. purity: 99%
TARGETMOL CHEMICALS INC K777 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. K777 is a potent orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain which is the major cysteine protease of Trypansoma cruzi and cathepsins B and L. K777 targets cathepsin-mediated cell entry and wxibits a broad-spectrum antiviral activity. K777 inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87 nM and 0.68 nM respectively. purity: 99%
TARGETMOL CHEMICALS INC ISA-2011B 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ISA-2011B is an inhibitor of PIP5K1(alpha) and can be used in anticancer studies. purity: 100%
TARGETMOL CHEMICALS INC ALPHAVBETA1 INTEGRIN-IN- 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (alpha)v(beta)1 integrin-IN-1 is a potent and selective inhibitor of (alpha)v(beta)1 integrin (IC50 of 0.63 nM) with antifibrotic effects. purity: 99%
TARGETMOL CHEMICALS INC IOPROMIDE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Iopromide (Iopromidum) is a low osmolar non-ionic contrast agent for intravascular use. purity: 99%
TARGETMOL CHEMICALS INC DIDESMETHYL CARIPRAZINE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Didesmethyl cariprazine a metabolite of Cariprazine is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a potent D3 preference D3/D2 receptor partial agonist of dopamine for the treatment of schizophrenia bipolar mania and depression with a high affinity for d3 and d2 receptors and a moderate affinity for 5-HT 1A receptors. purity: 99%
TARGETMOL CHEMICALS INC BALOXAVIR 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. purity: 99%
TARGETMOL CHEMICALS INC ABAPERIDONE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound that reduces basal hsp70 mRNA expression in rat striatum and prefrontal cortex. expression in the striatum and prefrontal cortex of rats. purity: 94%
TARGETMOL CHEMICALS INC TIGEMONAM 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Tigemonam is a monobactam. Tigemonam has potent activity against Gram-negative aerobic bacterial pathogens. purity: 99%
TARGETMOL CHEMICALS INC S-WILLARDIINE 50MG
Also available in 5 mg 10 mg 100 mg and bulk. Please contact Fisher for quotes. (S)-Willardiine (L-willardiine) is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 uM). purity: 99%
TARGETMOL CHEMICALS INC UMIBECESTAT 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1 respectively. Umibecestat can be used for the research of alzheimer's disease. purity: 100%
TARGETMOL CHEMICALS INC TCMDC-135051 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM). purity: 98%
TARGETMOL CHEMICALS INC SC57666 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1. purity: 99%