Benzoxazines
TARGETMOL CHEMICALS INC ZINC00640089 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ZINC00640089 is a selective lipid carrier protein-2 (LCN2) inhibitor. ZINC00640089 inhibited cell proliferation and cell viability and reduced AKT phosphorylation in SUM149 cells. ZINC00640089 can be used to study inflammatory breast cancer (IBC). purity: 99%
TARGETMOL CHEMICALS INC R 59-022 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC502.8 µM) that inhibits the phosphorylation of OAG to OAPA.R 59-022 enhances thrombin-induced triglyceride production in platelets and inhibits the production of phosphatidic acid in neutrophils. R 59-022 enhances thrombin-induced diglyceride production in platelets and inhibits phosphatidic acid production in neutrophils. purity: 97%
TARGETMOL CHEMICALS INC MTOR INHIBITOR 9D 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm and can be used for the treatment of leukemia skin cancer breast cancer lung cancer and colon cancer. purity: 98%
TARGETMOL CHEMICALS INC ZY-19489 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ZY-19489 is an antimalarial compound that is a potential single-dose cure for Plasmodium falciparum and Plasmodium vivax malaria. It has received orphan drug designation from the FDA. purity: 98%
TARGETMOL CHEMICALS INC SH-4-54 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SH-4-54 is a most potent small molecule nonphosphorylated STAT3 inhibitor. purity: 99%
TARGETMOL CHEMICALS INC KT-362 FREE BASE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease. purity: 99%
TARGETMOL CHEMICALS INC BAY 2965501 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGK(zeta)) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer. purity: 99%
TARGETMOL CHEMICALS INC HMAO-B-IN-4 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. hMAO-B-IN-4 is a selective reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B IC50=0.067 uM Ki= 0.03 uM hMAO-A IC50= 33.82 uM). purity: 99%
TARGETMOL CHEMICALS INC RALTITREXED 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Raltitrexed (D1694)(IC50 of 9 nM) a thymidylate synthase inhibitor is used for the inhibition of L1210 cell growth. purity: 99%
TARGETMOL CHEMICALS INC TILIQUINOL 25MG
Also available in 50 mg 100 mg 200 mg 500 mg and bulk. Please contact Fisher for quotes. Tiliquinol (NSC-130828) (NSC-130828) is a non-absorbed luminal agent with anti-amoebic properties that is often used in conjunction with tibroquinol. It is commonly employed in the study and investigation of amebic liver abscesses. purity: 99%
TARGETMOL CHEMICALS INC SIPONIMOD 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BAF312 (Siponimod (BAF-312)) a next-generation S1P receptor modulator is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibits >1000-fold over S1P2 S1P3 and S1P4 receptors. purity: 99%
TARGETMOL CHEMICALS INC JAK3-IN-14 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JAK3-IN-14 is a potent selective and orally active FLT3 inhibitor with IC50s of ∼40 8 and 4 nM for FLT3-WT FLT3-D835Y and FLT3-D835H respectively. purity: 98%
TARGETMOL CHEMICALS INC SIRTINOL 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sirtinol is a selective SIRT1/2 inhibitor (IC50 131/38 uM). purity: 99%
TARGETMOL CHEMICALS INC CALCIFEDIOL 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Calcifediol (U 32070E)(Ki of 3.9 uM) a major circulating metabolite of vitamin D3 works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA. purity: 99%
TARGETMOL CHEMICALS INC HC-030031 100MG
Also available in 10 mg 50 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2±0.2 and 5.3±0.2 uM respectively. purity: 99%