Biotin and derivatives
Medchemexpress LLC Biotin-PEG5-NHS ester | 98.0% | 632.72 | 100 MG
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker and a polyethylene glycol-containing bioconjugation reagent. It is used in scientific research for constructing highly sensitive biosensors, developing targeted drug delivery systems (e.g., liposome modification), immunofluorescence imaging, and protein affinity purification. It serves as a tool for precise labeling and functionalization of biomolecules.
- Heterobifunctional crosslinker.
- Polyethylene glycol-containing bioconjugation reagent.
- Specific introduction of biotin tags onto molecules with primary amine groups (-NH2), such as proteins, antibodies, and polypeptides, or material surfaces.
- NHS ester group reacts rapidly with amine groups under mild conditions to form stable amide bonds.
- Intermediate PEG5 chain acts as a flexible spacer arm, increasing spatial freedom and improving water solubility while reducing non-specific adsorption.
Medchemexpress LLC Biotin-PEG7-maleimide | 1898221-65-2 | 99.4% | 745.88 g/mol | C33H55N5O12S | 5 MG
Biotin-PEG7-Maleimide is a biotinylation reagent that reacts specifically with thiol (-SH) groups via a maleimide linker. It is used to attach biotin to thiol-containing molecules and as a linker in drug-linker conjugates such as antibody-drug conjugates (ADCs).
- Reacts selectively with thiol groups (-SH).
- Contains a PEG7 spacer to improve solubility and flexibility.
- Facilitates biotinylation for detection, pull-down, and affinity capture.
- Suitable for drug-linker conjugates, including ADC development.
- Molecular weight 745.88 g/mol.
- CAS number 1898221-65-2.
- Purity 99.4%.
Medchemexpress LLC Amino-PEG11-amine | 479200-82-3 | 95.0% | 100 MG
Amino-PEG11-amine is a PEG-based PROTAC linker designed to combine mono diethylstilbestrol (DES)-based ligands. This offers an alternative approach for creating more selective and active ER antagonists, useful in the endocrine treatment of breast cancer. The product appears as an oil with a white to off-white color. Its molecular weight is 544.68 and its formula is C24H52N2O11. This product is for research use only and not for sale to patients.
- PEG-based PROTAC linker
- Combines mono diethylstilbestrol (DES)-based ligands
- Supports development of selective ER antagonists
- Potential for breast cancer endocrine therapy
- Appears as an oil
- Color: white to off-white
- Molecular weight: 544.68
- Chemical formula: C24H52N2O11
- For research use only
Medchemexpress LLC CCND3 protein, human (biotinylated, MBP, His, Flag) | >85.0% | 20UG
Recombinant human CCND3 protein, biotinylated and fused to an N-terminal MBP with His and Flag tags, expressed in E. coli. The construct corresponds to CCND3 residues M1-L292 and is supplied in small research quantities (example: 20 μg). Characterization by reducing SDS-PAGE shows an apparent molecular weight of ~80 kDa and purity greater than 85%; consult the Certificate of Analysis for lot-specific data and storage instructions.
- Biotinylated for affinity capture and detection.
- N-terminal MBP fusion improves solubility.
- His and Flag tags enable purification and detection.
- Includes CCND3 residues M1-L292 for target-specific studies.
- Characterized by SDS-PAGE with >85% purity.
- Provided in small research-use quantities suitable for assay development.