Biotin and derivatives
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 258.34 g/mol | C10H18N4O2S | 1 ML
Biotin hydrazide is a carbonyl-reactive biotinylation reagent used to label oxidized glycans, glycoproteins, and other carbonyl-containing biomolecules. It is supplied as a solid or as a 10 mM solution in DMSO for use in conjugation, detection, and enrichment workflows.
- Reacts with carbonyl groups to form stable hydrazone linkages.
- Supplied as solid or as a 10 mM solution in DMSO for convenience.
- Enables biotin-based detection and affinity purification workflows.
- Soluble in DMSO and moderately soluble in water, with solubility data provided.
- Stable when stored under recommended temperatures for long-term use.
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 98.7% | 258.34 g/mol | C10H18N4O2S | 1 G
Biotin hydrazide is a carbonyl-reactive biotinylation reagent that forms hydrazone linkages with oxidized carbohydrates and other carbonyl groups. It is used to introduce a biotin tag for detection, affinity capture, and enrichment of labeled proteins and glycoconjugates in biochemical assays and proteomics workflows.
- Reacts selectively with aldehydes and ketones after oxidation.
- Enables streptavidin-based detection and affinity purification.
- Suitable for labeling glycoproteins following periodate oxidation.
- Supplied as a solid reagent for solution preparation and storage.
- High purity for reproducible analytical and preparative work.
Medchemexpress LLC Bis-PEG25-NHS ester | 2221948-96-3 | 99.8% | 1413.55 g/mol | C62H112N2O33 | 250 MG
Bis-PEG25-NHS ester is a homobifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester groups, used for amine-directed bioconjugation in PROTAC and ADC synthesis. It provides a hydrophilic spacer to improve solubility and facilitates cleavable linker chemistry.
- High purity (99.8%).
- Homobifunctional PEG linker with two NHS ester groups.
- Molecular weight 1413.55 g/mol and formula C62H112N2O33.
- Suitable for PROTAC and ADC linker chemistry and general amine-directed conjugation.
- Available in multiple pack sizes including 25 mg, 50 mg, 100 mg, 250 mg, 500 mg, and 1 g.
- Store sealed, away from moisture at -20°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
Medchemexpress LLC Biotin-lc-lc-nhs | 89889-52-1 | 98.0% | 567.70 | C26H41N5O7S | 25 MG
Biotin-LC-LC-NHS is an N-hydroxysuccinimide (NHS) ester biotinylation reagent with dual long-chain spacers. It covalently attaches biotin to primary amines on proteins, antibodies, and small molecules for labeling, detection, or affinity capture. Handle using appropriate safety precautions and store protected from light at -20°C.
- NHS ester reactive toward primary amines.
- Dual long-chain spacers reduce steric hindrance during labeling.
- Molecular weight 567.70 and formula C26H41N5O7S for precise calculations.
- Purity 98.0% for research-grade applications.
- High solubility in DMSO (100 mg/mL) with recommended freshly opened DMSO.
- Store at -20°C, protect from light, and handle under standard laboratory safety practices.