Biotin and derivatives
Medchemexpress LLC Biotin-C5-azide | 1260586-88-6 | 98.9% | 255.34 g/mol | C10H17N5OS | 10 MG
Biotin-C5-Azide is a biotinylation reagent containing a terminal azide group for click chemistry. It is intended for research use to prepare biotinylated conjugates via copper-catalyzed or strain-promoted azide-alkyne cycloaddition.
Medchemexpress LLC Bis-biotin-PEG23 | 293298-36-9 | 97.8% | C68H128N6O27S2 | 10MG
Bis-Biotin-PEG23 is a polyethylene glycol (PEG)-based PROTAC linker bearing biotin groups at both termini, designed to facilitate the assembly of bifunctional molecules and to introduce biotin affinity tags for pull-down or detection assays. It is supplied as a solid with high specified purity and is intended for research applications requiring a hydrophilic, flexible spacer.
- Two terminal biotin groups for affinity capture and detection.
- Long PEG23 spacer provides flexibility and improved solubility.
- High purity suitable for analytical and synthetic workflows.
- Solid form allows convenient handling and storage.
- Storage under low temperature and inert atmosphere preserves stability.
Medchemexpress LLC Sulfo-Cy3-NHS disodium | 865.90 g/mol | C36H41N3Na2O13S3 | 10 MG
Sulfo-Cy3-NHS disodium is a water-soluble Cyanine3 (Cy3) derivative bearing an NHS ester for amine-reactive conjugation. The sulfonate groups increase aqueous solubility, making this reagent suitable for labeling proteins, peptides, and antibodies for fluorescence detection and imaging.
- Water-soluble NHS ester for efficient labeling of primary amines.
- Improved aqueous solubility due to sulfonate groups.
- Suitable for conjugation to proteins, antibodies, and peptides.
- Enables fluorescence detection and imaging applications.
- Stable solid form for routine laboratory handling and storage per manufacturer instructions.
Medchemexpress LLC PD-L1 Human Biotin 20ug
Recombinant, biotinylated human PD-L1 produced in HEK293 cells and supplied as a lyophilized 20 μg vial for research use. The protein includes C-terminal human Fc and Avi tags, is characterized for purity and molecular mass, and exhibits specific binding activity suitable for PD-1/PD-L1 interaction and immunoassay applications.
- Expressed in HEK293 mammalian cells.
- Contains C-terminal human Fc and Avi tags.
- Site-specific biotinylation via Avi tag.
- Purity greater than 95% by reducing SDS-PAGE.
- Lyophilized from 20 mM PB, 150 mM NaCl, pH 7.4.
- Predicted molecular mass 54.2 kDa; apparent 70-95 kDa by SDS-PAGE.
- Demonstrated binding activity with ED50 of 15.30 ng/mL.
- Store frozen and aliquot after reconstitution for long-term stability.
Apexbio Technology LLC Concanavalin A (Con A)-Biotin 5mg(5 mg/mL)
Concanavalin A (Con A) is a lectin protein derived from Canavalia ensiformis (jack bean) with a molecular weight of approximately 104 kDa Each subunit can bind one Ca2 and one Mn2 ion and contains a carbohydrate-binding site Upon binding these metal ions Con A specifically binds to glycoproteins glycolipids and carbohydrates containing -D-glucose and -D-mannose residues Biotin is a small-molecule water-soluble vitamin that exhibits very strong affinity to avidin Concanavalin A-Biotin is a labeled protein conjugate composed of Concanavalin A linked to biotin widely used in biological research especially for detecting and quantifying biomolecules containing specific carbohydrate structures through immunohistochemistry (IHC) immunocytochemistry (ICC) and enzyme-linked immunosorbent assay (ELISA)
Medchemexpress LLC IL-13 Human Biotin 100ug
IL-13 protein is a cytokine involved in allergic inflammation immune response to parasites and B cell proliferation IL-13 Protein Human (Biotinylated HEK293 Avi-His) is the recombinant human-derived IL-13 protein expressed by HEK293 with C-Avi C-6 His labeled tag
Medchemexpress LLC M-PEG-NHS ester (MW 20000) | 92451-01-9 | 98.0% | (C2H4O)nC7H9NO5 | 25 MG
M-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are compounds that consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. This mechanism allows PROTACs to utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Biotin-PEG12-NHS ester | 1934296-88-4 | 99.31% | C41H72N4O18S | 25 MG
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Utilizes intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Boc-N-PEG1-C2-NHS ester | 1260092-55-4 | 97.0% | C14H22N2O7 | 250 MG
Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Selectively degrades target proteins
- Utilizes the intracellular ubiquitin-proteasome system
Medchemexpress LLC Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) | 138529-46-1 | 98.0% | 250 MG
Biotin-DADOO is a biotin-containing amine compound and a biotinylation reagent. As an amino component, it participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. It can be conjugated with carboxymethyl cellulose derivatives and is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A.
- Is a biotin-containing amine compound.
- Functions as a biotinylation reagent.
- Participates in nucleophilic ring-opening reactions during the synthesis of biotinylated inhibitor derivatives.
- Can be conjugated with carboxymethyl cellulose derivatives.
- Is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays.
- Can be used in the research of influenza A.
Medchemexpress LLC Tri-GalNAc biotin | 3062597-46-7 | 99.8% | 1916.19 | 5 MG
Tri-GalNAc biotin is a biotinylated ASGPR (Asialoglycoprotein receptor) ligand. It promotes cellular uptake of neutravidin (NA) via ASGPR and delivers neutravidin to lysosomes for degradation. This compound can be used for research of LYsosome TArgeting Chimera (LYTAC).
- Promotes cellular uptake of neutravidin (NA) via ASGPR.
- Delivers neutravidin to lysosomes for degradation.
- Facilitates ASGPR-dependent cellular uptake of fluorescently labeled NeutrAvidin (NA-650).
- Useful for research of LYsosome TArgeting Chimera (LYTAC).
Medchemexpress LLC Rhodamine B NHS ester | 144700-55-0 | 96.9% | 576.08 | C32H34ClN3O5 | 10 MG
Rhodamine B NHS ester is an N-hydroxysuccinimide (NHS) activated fluorescent dye for covalent labeling of primary amines in proteins, peptides, and other biomolecules. It forms stable amide bonds to introduce a rhodamine fluorophore for fluorescence microscopy, flow cytometry, and biochemical assays.
- NHS-activated for efficient and selective amine coupling.
- Bright rhodamine fluorescence suitable for microscopy and flow cytometry.
- Molecular weight 576.08 g/mol and formula C32H34ClN3O5.
- High purity (~96.9%) for reliable labeling performance.
- Available in small research pack sizes for convenient use.
Sigma Aldrich Fine Chemicals Biosciences Biotin meets USP testing specifications | 58-85-5 | MFCD00005541 | 5G
Biotin meets USP testing specifications | Purity: 97.5-102.0% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 5G
Medchemexpress LLC BHQ-1 NHS | 916753-61-2 | C30H31N7O7 | 5 MG
BHQ-1 NHS is a fluorescent dye used for research purposes. It is directly labeled by fluorescently labeled nucleotide and is not intended for patient use.
- Fluorescent dye
- Purity 96.65%
- Solid appearance
- Brown to black color
- Molecular weight 601.61
- Used in cell staining analysis
- Used in cell function analysis
- Applicable in nucleic acid dyes
Chem-Impex International, Inc. Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester | 72040-63-2 | MFCD00065502 | 100MG
Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester, 72040-63-2, MFCD00065502, 100MG