Azido-PEG9-NHS ester is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds containing DBCO or BCN groups. For optimal stability, store in a tightly sealed container in a cool, well-ventilated area, away from direct sunlight and ignition sources.
- Can be used in the synthesis of PROTACs
- Features an Azide group for click chemistry applications
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- Recommended storage at -20°C for up to 3 years in pure form