Dithiolanes
Apexbio Technology LLC Fasudil (HA-1077) HCl 105628-07-7 500mg
Fasudil HA-1077 HCl (CAS 105628-07-7) is a small-molecule inhibitor targeting Rho-associated protein kinase (ROCK) a serine/threonine kinase It is designed to inhibit ROCK thereby regulating cellular processes such as proliferation migration and apoptosis Fasudil HA-1077 HCl exerts its biological activity primarily through ROCK inhibition In cell-based studies Fasudil inhibits proliferation and migration and promotes apoptosis in cancer cell models including bladder carcinoma (5637 UM-UC-3) and oral squamous cell carcinoma (SCC-4) its ROCK inhibitory activity shows an IC50 value of approximately 0 74 M Based on these pharmacological properties Fasudil HA-1077 HCl holds research potential in oncology and disease models involving ROCK-mediated signaling
eMolecules 1077-28-7 | Alpha Lipoic acid | Key Organics/BIONET - Building Blocks | MFCD00005474 | 206.320 | C8H14O2S2 | 97.000 | OC(=O)CCCCC1CCSS1 | 4mg | 385550107
Alpha Lipoic acid | Key Organics/BIONET - Building Blocks | 1077-28-7 | MFCD00005474 | 206.320 | C8H14O2S2 | 97.000 | OC(=O)CCCCC1CCSS1 | 4mg | 385550107
Medchemexpress LLC R-(+)-α-lipoic acid | 1200-22-2 | MFCD01631142 | 99.4% | 206.33 | C8H14O2S2 | 10 MG
Analytical standard of (R)-(+)-α-lipoic acid intended for research and analytical applications such as HPLC, GC, and MS. It is used as a quantitative and qualitative reference material for method development, calibration, and validation in biochemical and pharmaceutical analysis.
- High purity suitable for analytical assays (99.36%).
- Defined chemical identity for accurate reference (C8H14O2S2, MW 206.33).
- Compact 10 mg packaging for analytical use and method validation.
- Stable under recommended storage; consult the certificate of analysis for handling.
Medchemexpress LLC α-Lipoic Acid | 1077-28-7 | MFCD00005474 | 206.33 | 5 G
α-Lipoic Acid (Thioctic acid) is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 to construct the self-assembled nanoaggregate CPUL1-LA NA, which demonstrates improved antitumor efficacy compared to CPUL1.
- Antioxidant
- Essential cofactor of mitochondrial enzyme complexes
- Inhibits NF-κB-dependent HIV-1 LTR activation
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells
- Can be used to construct self-assembled nanoaggregates with improved antitumor efficacy
Medchemexpress LLC 4-Hydroxyisophthalic acid | 636-46-4 | 99.5% | C8H6O5 | 10 MM 1 ML
This compound activates antioxidant enzymes (such as catalase and superoxide dismutase) and scavenges free radicals, demonstrating antioxidant properties. It also activates AChE and BChE, which enhances neuronal function and improves neurobehavioral defects. Additionally, it can ameliorate cognitive defects and circadian rhythm disorders.
- Activates antioxidant enzymes and scavenges free radicals.
- Exhibits antioxidant properties.
- Enhances neuronal function.
- Improves neurobehavioral defects.
- Ameliorates cognitive defects and circadian rhythm disorders.
Medchemexpress LLC Alpha-Lipoic acid (Standard) | 1077-28-7 | 206.33 | 25 MG
Alpha-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid, intended for research and analytical applications. It functions as an antioxidant and is an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, demonstrating improved antitumor efficacy compared to CPUL1.
- Used as a reference standard in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Inhibits NF-κB-dependent HIV-1 LTR activation.
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.
- Essential cofactor of mitochondrial enzyme complexes.
eMolecules 1200-22-2 | (R)-a-Lipoic acid | Chem-Impex | MFCD00005474 | 206.320 | C8H14O2S2 | 99.000 | OC(=O)CCCCC1CCSS1 | 25g | 603120139
(R)-a-Lipoic acid | Chem-Impex | 1200-22-2 | MFCD00005474 | 206.320 | C8H14O2S2 | 99.000 | OC(=O)CCCCC1CCSS1 | 25g | 603120139