Dithiolanes
Selleck Chemical LLC ()-a-Lipoic acid S3998-25mg
( )- -Lipoic acid ((R)-( )- -Lipoic acid -Lipoic acid Alpha-Lipoic acid) a physiological form of thioctic acid is a strong antioxidant that relieves diabetic neuropathic symptoms It shows superior antioxidative effects to its racemate R( )- -lipoic acid is an essential cofactor of mitochondrial enzyme complexes R( )- -lipoic acid inhibits NF- B-dependent HIV-1 LTR activation
![Alkali Scientific DL Thioctic Acid [DL a Lipoic acid], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660394.jpg-250.jpg)
Alkali Scientific DL Thioctic Acid [DL a Lipoic acid], 1 G
DL Thioctic Acid (DL Alpha Lipoic Acid), 1G, is a potent antioxidant used in various biological and chemical applications. This formulation is a racemic mixture of both the D- and L- forms of alpha-lipoic acid, a sulfur-containing fatty acid that plays a crucial role in cellular metabolism and acts as a cofactor for several mitochondrial enzymes. In addition to its antioxidant properties, DL Alpha Lipoic Acid has shown therapeutic potential in neuroprotective and anti-inflammatory treatments. It is commonly used in laboratory research for cell protection studies and metabolic assays and is also a key ingredient in pharmaceutical formulations for supporting liver health and treating diabetic neuropathy.
Medchemexpress LLC α-Lipoic Acid sodium | 2319-84-8 | 228.31 | 10 G
α-Lipoic Acid sodium is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be utilized in the construction of self-assembled nanoaggregates to enhance antitumor efficacy.
- Acts as an antioxidant.
- Functions as an essential cofactor of mitochondrial enzyme complexes.
- Inhibits NF-κB-dependent HIV-1 LTR activation.
- Induces endoplasmic reticulum stress-mediated apoptosis in hepatoma cells.
- Can be used to construct self-assembled nanoaggregates with improved antitumor efficacy.
Sigma Aldrich Fine Chemicals Biosciences 5-Carboxyfluorescein BioReagent, suitable for fluorescence, >=95% (HPLC) | 76823-03-5 | MFCD00036874 | 100MG
5-Carboxyfluorescein BioReagent, suitable for fluorescence, >=95% (HPLC) | Purity: >=95% (HPLC) | Mol Wt: 376.32 | 76823-03-5 | MFCD00036874 | 100MG
Cayman Chemical R-a-LIpoIc AcId 5g
A cyclic disulfide antioxidant; acts as a cofactor in 2-oxo dehydrogenase complex reactions and is reduced to DHLA; decreases serum levels of MDA and increases the activity of SOD and T-AOC in a mouse model of D-galactose-induced accelerated senescence at 100 mg/kg per day; reduces the escape latency in the Morris water maze compared to both D-galactose and vehicle control groups and rescues decreases in neural progenitor cell proliferation in the hippocampal dentate gyrus at 100 mg/kg per day
Medchemexpress LLC α-Lipoic Acid (Thioctic acid) | 1077-28-7 | MFCD00005474 | 206.33 | 1 ML
α-Lipoic Acid (Thioctic acid) is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 (HY-151802) to form self-assembled nanoaggregate CPUL1-LA NA, which shows improved antitumor efficacy compared to CPUL1. This product is for research use only.
- Plays an essential role in mitochondrial bioenergetics.
- Reduces lipid accumulation in the liver.
- Increases NAD+/NADH ratio in HepG2 cells.
- Increases SIRT1 activity in HepG2 cells.
- Increases phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in HepG2 cells.
- Markedly reduces visceral fat mass in C57BL/6J mice.
- Inhibits appetite and causes significant weight loss in mice.
Sigma Aldrich Fine Chemicals Biosciences Thioctic acid for system s
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Selleck Chemical LLC ()-a-Lipoic acid S3998-1g
( )- -Lipoic acid ((R)-( )- -Lipoic acid -Lipoic acid Alpha-Lipoic acid) a physiological form of thioctic acid is a strong antioxidant that relieves diabetic neuropathic symptoms It shows superior antioxidative effects to its racemate R( )- -lipoic acid is an essential cofactor of mitochondrial enzyme complexes R( )- -lipoic acid inhibits NF- B-dependent HIV-1 LTR activation
Medchemexpress LLC Lipoic acid (standard) | 1200-22-2 | 99.83% | 206.33 | 50 MG
Lipoic acid (Standard) is the analytical standard of Lipoic acid, intended for research and analytical applications. Lipoic acid is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
- Used as a reference standard supplied assay
- Commonly utilized in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC α-Lipoic acid sodium | 2319-84-8 | 228.31 | 1 G
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation. It also induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells and can be used with CPUL1 to form self-assembled nanoaggregate CPUL1-LA NA, which shows improved antitumor efficacy.
- Antioxidant
- Essential cofactor of mitochondrial enzyme complexes
- Inhibits NF-κB-dependent HIV-1 LTR activation
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells
- Can be used with CPUL1 to form self-assembled nanoaggregate CPUL1-LA NA
Medchemexpress LLC Lipoic acid | 1200-22-2 | 968259 | 99.9% | 206.33 | 5 G
Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
- Antioxidant
- Essential cofactor of mitochondrial enzyme complexes
- More effective than racemic lipoic acid
- Biosynthesized in humans and essential for aerobic metabolism
- Nutritionally and therapeutically preferred form due to its "vitamin-like" role in metabolism
- Exists in nature